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Serving hundreds of leading biopharmaceutical companies globally:

Mallinckrodt
Cerilliant
US Department of Justice
McKesson
Colorcon
Fuji
QuintilesIMS
Argus Health
Farmers Insurance

Generated: April 24, 2018

DrugPatentWatch Database Preview

OVIDE Drug Profile

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When do Ovide patents expire, and when can generic versions of Ovide launch?

Ovide is a drug marketed by Taro Pharm and is included in one NDA. There are two patents protecting this drug and one Paragraph IV challenge.

This drug has ten patent family members in seven countries.

The generic ingredient in OVIDE is malathion. There are three drug master file entries for this compound. Four suppliers are listed for this compound. Additional details are available on the malathion profile page.
Summary for OVIDE
Drug patent expirations by year for OVIDE
Pharmacology for OVIDE
Medical Subject Heading (MeSH) Categories for OVIDE
Synonyms for OVIDE
((Dimethoxyphosphinothioyl)thio)butanedioic acid diethyl ester
[(DIMETHOXYPHOPHINOTHIOYL)THIO]BUTANEDIOIC ACID, DIETHYL ESTER
[(dimethoxyphosphinothioyl)thio]butanedioic acid diethyl ester
[(Dimethoxyphosphinothioyl)thio]butanedioic acid, diethyl ester
0,2-bis(ethoxycarbonyl)ethyl] dithiophosphate
1,2-D.(ethoxycarbonyl)dimethyl phosphorothiolothionate
1,2-Di(ethoxycarbonyl)ethyl O,O-dimethyl phosphordithioate
1,2-Di(ethoxycarbonyl)ethyl O,O-dimethyl phosphorodithioate
1,4-diethyl 2-{[dimethoxy(sulfanylidene)-|E5-phosphanyl]sulfanyl}butanedioate
1,4-diethyl 2-{[dimethoxy(sulfanylidene)-$l;{5}-phosphanyl]sulfanyl}butanedioate
1,O-dimethyl phosphordithioates
11096-67-6
11130-60-2
121-75-5
121M755
12737-19-8
12767-62-3
141263-96-9
141318-03-8
2-(dimethoxyphosphinothioylthio) butanedioic acid diethyl ester
75513-83-6
8059HC
AB00053015_02
AC 26691
AC1L1H72
ACMC-20n0ay
AI3-17034
AKOS015897264
American cyanamid 4,049
AN-22853
AS-13786
BC203973
BDBM85372
BRN 1804525
BSPBio_002305
Butanedioic acid, ((dimethoxyphosphinothioyl)-thio)-, diethyl ester, (+-)-
Butanedioic acid, ((dimethoxyphosphinothioyl)thio)-, diethyl ester
Butanedioic acid, [(dimethoxyphosphinothioyl)thio]-, diethyl ester
Butanedioic acid, [(dimethoxyphosphinothioyl)thio]-, diethyl ester, (R)-
C-20018
C07497
C10H19O6PS2
Calmathion
Camathion
Carbafos
Carbethoxy malathion
Carbetovur
Carbetox
Carbofos
Carbophos
CAS_121-75-5
CAS-121-75-5
CC-30125
CCG-39152
CCRIS 368
Celthion
CHEBI:6651
Chemathion
CHEMBL1200468
Cimexan
Cleensheen
Compound 4049
CS-4416
CTK8E8095
Cythion
D00534
D0K3LW
DB00772
Derbac-M
detm ol ma
Detmol MA
Dicarbethoxyethyl-O,O-dimethyldithiophosphate
Dicarboethoxyethyl O,O-dimethyl phosphorodithioate
Diethyl ((dimethoxyphosphinothioyl)thio)butanedioate
Diethyl (+-)-mercaptosuccinate, S-ester with O,O-dimethyl phosphorodithioate
Diethyl (dimethoxyphosphinothioylthio) butanedioate
Diethyl (dimethoxyphosphinothioylthio)succinate
diethyl [(dimethox yphosphinothioyl)thio]butanedioate
diethyl [(dimethoxyphosphinothioyl)thio]butanedioate
Diethyl [(dimethoxyphosphinothoiyl)thio]butanedioate
diethyl 2-((dimethoxyphosphorothioyl)thio)succinate
Diethyl 2-(dimethoxyphosphinothioylthio)succinate
diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]butanedioate
Diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate #
diethyl 2-[(dimethoxyphosphorothioyl)thio]succinate
diethyl 2-dimethoxyphosphinothioylsulfanylbutanedioate
Diethyl mercaptosuccinate S-ester with O,O-dimethyl phosphorodithioate
Diethyl mercaptosuccinate S-ester with O,O-dimethylphosphorodithioate
Diethyl mercaptosuccinate, O,O-dimethyl dithiophosphate, S-ester
Diethyl mercaptosuccinate, O,O-dimethyl phosphoro dithioate
Diethyl mercaptosuccinate, O,O-dimethyl phosphorodithioate
Diethyl mercaptosuccinate, O,O-dimethyl thiophosphate
Diethyl mercaptosuccinate,O-dimethyl dithiophosphate, S-ester
Diethyl mercaptosuccinate,O-dimethyl phosphorodithioate
Diethyl mercaptosuccinate,O-dimethyl thiophosphate
Diethyl mercaptosuccinic acid O,O-dimethyl phosphorodithioate
Diethyl mercaptosuccinic acid, S-ester of O,O-dimethyl phosphorodithioate
Diethyl mercaptosuccinic acid,O-dimethyl phosphorodithioate
Diethyl(dimethoxythiophosphorylthio)succinate
Dimeth yl phosphorodithioate of diethyl mercaptosuccinate
Dimethyl dithiophosphate of diethyl mercaptosuccinate
Dimethyl phosphorodithioate of diethyl mercaptosuccinate
Dithiophosphate de O,2-dicarboethoxyethyle)
Dithiophosphate de O,O-dimethyle et de S-(1,2-dicarboethoxyethyle)
Dithiophosphate de O,O-dimethyle et de S-(1,2-dicarboethoxyethyle) [French]
DivK1c_006482
Dorthion
DR001554
DSSTox_CID_791
DSSTox_GSID_20791
DSSTox_RID_75791
DTXSID4020791
EINECS 204-497-7
EL 4049
Emmatos
Emmatos extra
ENT 17,034
Ethiolacar
Etiol
Experimental insecticide 4049
Extermathion
Flair
Fog 3
Forthion
Fosfothion
Fosfotion
Fosfotion 550
Four thousand forty-nine
FT-0603323
Fyfanon
Gammaxine
Hilthion
Hilthion 25wdp
HMS3264A04
HSDB 665
HY-B0943
I09-0505
IFO 13140
InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3
Insecticide no. 4049
J-004630
J10314
JXSJBGJIGXNWCI-UHFFFAOYSA-
JXSJBGJIGXNWCI-UHFFFAOYSA-N
K-1631
Karbofos
KBio1_001426
KBio2_002286
KBio2_004854
KBio2_007422
KBio3_001805
KBioGR_001025
KBioSS_002288
Kill-A-Mite
Kop-thion
Kop-Thionkypfosmalacide
KS-00001F9I
Kypfos
L001138
Latka 4049
Latka 4049 [Czech]
Lice Rid
LS-654
Malacide
Malafor
Malagran
Malakill
Malamar
Malamar 50
Malaphele
Malaphos
Malasol
Malaspray
Malataf
Malathiazol
malathine
malathion
malathion ,s-(1,2-dicarbethoxyl)
Malathion (old ID)
Malathion (USP)
Malathion [USP:BAN]
Malathion [USP]
Malathion 10 microg/mL in Cyclohexane
Malathion 100 microg/mL in Cyclohexane
Malathion 60
Malathion E.C.
Malathion E50
Malathion LV Concentrate
Malathion solution, 100 mug/mL in cyclohexane, PESTANAL(R), analytical standard
Malathion ULV
Malathion-2,3-14C
MALATHION, 96%
Malathion, analytical standard
Malathion, certified reference material, TraceCERT(R)
Malathion, European Pharmacopoeia (EP) Reference Standard
Malathion, PESTANAL(R), analytical standard
Malathion, United States Pharmacopeia (USP) Reference Standard
Malathion, vial of 1 g, analytical standard
Malathione
Malathiozoo
Malathon
Malathyl
Malathyne
Malation
Malation [Polish]
Malatol
Malatox
Maldison
Malmed
Malphos
Maltox
Maltox MLT
Mercaptosuccinic acid diethyl ester
mercaptosuccinic acid diethyl ester S-est er with O,O-dimethyl phosphorothioate
mercaptosuccinic acid diethyl ester S-ester with O,O-dimethyl phosphorothioate
Mercaptosuccinic acid diethyl ester, S-ester with O,O-dimethyl phosphorothioate
Mercaptosuccinic acid diethyl ester,O-dimethyl phosphorothioate
Mercaptothion
Mercaptotion
Mercaptotion [Spanish]
MET86C_SUPELCO
MLT
MolPort-003-665-439
Moscarda
NCGC00091902-01
NCGC00091902-02
NCGC00091902-03
NCGC00091902-05
NCGC00091902-06
NCGC00091902-07
NCGC00091902-08
NCGC00091902-09
NCGC00091902-11
NCI-C00215
NSC 6524
NSC-6524
NSC-755848
NSC6524
NSC755848
O,2-di(ethoxycarbamyl)ethyl phosphorothioate
O,2-dicarbethoxyethyl) dithiophosphate
O,2-dicarbethoxyethyl) phosphorodithioate
O,2-dicarbethoxyethyl) thiothionophosphate
O,2-dikarbetoxylethylditiofosfat
O,O-Dimethyl dithiophosphate diethylmercaptosuccinate
O,O-Dimethyl dithiophosphate of diethyl mercaptosuccinate
O,O-dimethyl phosphorodithioate ester of diethyl mercaptosuccinate
O,O-dimethyl S-( 1,2-dicarbethoxyethyl) dithiophosphate
O,O-Dimethyl S-(1,2-bis(ethoxycarbonyl)ethyl)
O,O-Dimethyl S-(1,2-bis(ethoxycarbonyl)ethyl) dithiophosphate
O,O-Dimethyl S-(1,2-dicarbethoxyethyl) dithiophosphate
O,O-Dimethyl S-(1,2-dicarbethoxyethyl) phosphorodithioate
O,O-Dimethyl S-(1,2-dicarbethoxyethyl) thiothionophosphate
O,O-Dimethyl S-(1,2-dicarbethoxyethyl)phosphorodithioate
O,O-Dimethyl S-1,2-di(ethoxycarbamyl)ethyl
O,O-Dimethyl S-1,2-di(ethoxycarbamyl)ethyl phosphorodithioate
O,O-Dimethyl S-1,2-di(ethoxycarbamyl)ethyl phosphorothioate
O,O-dimethyl S-1,2-di(ethoxycarbonyl)ethyl phosphorodithioate
O,O-dimethyl-S-(1,2-bis(ethoxycarbonyl)eth yl)dithiophosphate
O,O-dimethyl-S-(1,2-bis(ethoxycarbonyl)ethyl)dithiophosphate
o,o-Dimethyl-S-(1,2-di(ethoxycarbonyl)ethyl) phosphorodithioate
O,O-dimethyl-S-(1,2-dicarbethoxyethyl) thiothionophosphate
O,O-Dimethyl-S-1,2-(dicarbaethoxyaethyl)-dithiophosphat
O,O-Dimethyl-S-1,2-(dicarbaethoxyaethyl)-dithiophosphat [German]
O,O-Dimethyl-S-1,2-dikarbetoxylethylditiofosfat
O,O-Dimethyl-S-1,2-dikarbetoxylethylditiofosfat [Czech]
O,O-dimethyldithiophosphate diethyl mercaptosuccinate
O,O-Dimethyldithiophosphate diethylmercaptosuccinate
O,O-Dwumetylo-S-1,2-bis(karboetoksyetylo)-dwutiofosforan
O,O-Dwumetylo-S-1,2-bis(karboetoksyetylo)-dwutiofosforan [Polish]
Oleophosphothion
OMS 1
OR209211
OR209212
OR218931
Organoderm
Ortho Malathion
Ovide (TN)
Paladin
Pharmakon1600-00330021
Phosphorodithioic acid, O,O-dimethyl ester, S-ester with diethyl mercaptosuccinate
Phosphorodithioic acid,0-dimethyl ester, S-ester with diethyl mercaptosuccinate
Phosphothion
Prioderm
PS86_SUPELCO
Radotion
S-(1,2-Bis(aethoxy-carbonyl)-aethyl)-O,O-dimethyl-dithiophasphat
S-(1,2-Bis(aethoxy-carbonyl)-aethyl)-O,O-dimethyl-dithiophosphat
S-(1,2-Bis(aethoxy-carbonyl)-aethyl)-O,O-dimethyl-dithiophosphat [German]
S-(1,2-bis(carbethoxy)ethyl) O,O-dimethyl d ithiophosphate
S-(1,2-Bis(carbethoxy)ethyl) O,O-dimethyl dithiophosphate
S-(1,2-Bis(ethoxy-carbonyl)-ethyl)-O,O-dimethyl-dithiofosfaat
S-(1,2-Bis(ethoxy-carbonyl)-ethyl)-O,O-dimethyl-dithiofosfaat [Dutch]
S-(1,2-Bis(ethoxycarbonyl)ethyl) O,O-dimethyl phosphorodithioate
S-(1,2-Bis(etossi-carbonil)-etil)-O,O-dimetil-ditiofosfato
S-(1,2-Bis(etossi-carbonil)-etil)-O,O-dimetil-ditiofosfato [Italian]
S-(1,2-Di(ethoxycarbonyl)ethyl) dimethyl phosphorothiolothionate
S-(1,2-di(ethoxycarbonyl)ethyl) dimethylphosphorothiolothionate
S-(1,2-Dicarbethoxyethyl) O,O-dimethyl phosphorodithioate
S-(1,2-Dicarbethoxyethyl) O,O-dimethyldithiophosphate
S-(1,2-Dicarbethoxyethyl) O,O-dimethylphosphorodithioate
S-(1,O-dimethyl phosphorodithioate
S-(1,O-dimethyl-dithiofosfaat
S-(1,O-dimethyl-dithiophasphat
S-(1,O-dimetil-ditiofosfato
S-[1,2-Bis(carbethoxy)ethyl] O,O-dimethyl dithiophosphate
S-[1,2-Bis(ethoxycarbonyl)ethyl] O,O-dimethyl phosphorodithioate
S-[1,O-dimethyl dithiophosphate
S-[1,O-dimethyl phosphorodithioate
S-1,2-bis(ethoxycarbonyl)ethyl O,O-dimethyl dithiophosphate
S-1,2-Bis(ethoxycarbonyl)ethyl-O,O-dimethyl thiophosphate
S-1,O-dimethyl thiophosphate
Sadofos
Sadofos 30
Sadophos
SC-80447
SCHEMBL27358
SF 60
Siptox I
SPBio_001076
SpecPlus_000386
Spectrum_001795
Spectrum2_001228
Spectrum3_000813
Spectrum4_000653
Spectrum5_001936
SR-01000942243
SR-01000942243-1
Staeubol-Puder
Succinic acid, diethyl ester, S-ester with 0,0-dimethyl phosphorodithioate
Succinic acid, diethyl ester, S-ester with O,O-dimethyl phosphorodithioate
Succinic acid, mercapto-, diethyl ester, S-ester with O,O-dimethyl phosphorodithioate
Succinic acid, mercapto-, diethyl ester, S-ester with O,O-dimethylphosphorodithioate
Suleo M
Suleo-M
Sumitox
TAK
Taskil
TM-4049
Tox21_111175
Tox21_111175_1
Tox21_400048
TR-003531
Vegfru malatox
Vetiol
WLN: 2OV1YVO2 & SPS & O1 & O1
Zithiol

US Patents and Regulatory Information for OVIDE

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Taro Pharm OVIDE malathion LOTION;TOPICAL 018613-001 Aug 2, 1982 AT RX Yes Yes ➤ Sign Up ➤ Sign Up Y Y ➤ Sign Up
Taro Pharm OVIDE malathion LOTION;TOPICAL 018613-001 Aug 2, 1982 AT RX Yes Yes ➤ Sign Up ➤ Sign Up Y ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration

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Paragraph IV (Patent) Challenges for OVIDE
Drugname Dosage Strength RLD Submissiondate
➤ Subscribe Topical Lotion 0.5% ➤ Subscribe 2011-03-16

Non-Orange Book US Patents for OVIDE

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
8,957,238 Process for preparing malathion for pharmaceutical use ➤ Sign Up
8,039,657 Process for preparing malathion for pharmaceutical use ➤ Sign Up
8,536,155 Process for preparing malathion for pharmaceutical use ➤ Sign Up
Patent No. Title Estimated Patent Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Express Scripts
Fish and Richardson
Colorcon
Moodys
Cipla
Boehringer Ingelheim
Daiichi Sankyo
Johnson and Johnson
Julphar

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