OPVEE Drug Patent Profile

Which patents cover Opvee, and what generic alternatives are available?

Opvee is a drug marketed by Indivior and is included in one NDA. There is one patent protecting this drug.

This drug has eleven patent family members in eight countries.

The generic ingredient in OPVEE is nalmefene hydrochloride. There are four drug master file entries for this compound. Three suppliers are listed for this compound. Additional details are available on the nalmefene hydrochloride profile page.

DrugPatentWatch^® Litigation and Generic Entry Outlook for Opvee

A generic version of OPVEE was approved as nalmefene hydrochloride by PURDUE PHARMA LP on February 8^th, 2022.

Summary for OPVEE

International Patents:	11
US Patents:	1
Applicants:	1
NDAs:	1
Finished Product Suppliers / Packagers:	1
Formulation / Manufacturing:	see details
Drug Prices:	Drug price information for OPVEE
What excipients (inactive ingredients) are in OPVEE?	OPVEE excipients list
DailyMed Link:	OPVEE at DailyMed

See drug prices for OPVEE

Pharmacology for OPVEE

Drug Class	Opioid Antagonist
Mechanism of Action	Opioid Antagonists

Anatomical Therapeutic Chemical (ATC) Classes for OPVEE

N07BB	Drugs used in alcohol dependence
N07B	DRUGS USED IN ADDICTIVE DISORDERS
N07	OTHER NERVOUS SYSTEM DRUGS
N	Nervous system

US Patents and Regulatory Information for OPVEE

OPVEE is protected by one US patents and one FDA Regulatory Exclusivity.

Patents protecting OPVEE

FDA Regulatory Exclusivity protecting OPVEE

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Exclusivity Expiration
Indivior	OPVEE	nalmefene hydrochloride	SPRAY;NASAL	217470-001	May 22, 2023		RX	Yes	Yes			Y
Indivior	OPVEE	nalmefene hydrochloride	SPRAY;NASAL	217470-001	May 22, 2023		RX	Yes	Yes

International Patents for OPVEE

See the table below for patents covering OPVEE around the world.

Country	Patent Number	Title	Estimated Expiration
Canada	3044221	COMPOSITIONS ET METHODES DE TRAITEMENT D'UNE PRISE EXCESSIVE D'OPIOIDES (COMPOSITIONS AND METHODS FOR THE TREATMENT OF OPIOID OVERDOSE)
Japan	2023140359	オピオイド過剰摂取を処置するための組成物および方法 (COMPOSITIONS AND METHODS FOR TREATMENT OF OPIOID OVERDOSE)
Russian Federation	2019118465	КОМПОЗИЦИИ И СПОСОБЫ ЛЕЧЕНИЯ ПЕРЕДОЗИРОВКИ ОПИОИДАМИ
European Patent Office	3541386	COMPOSITIONS ET MÉTHODES DE TRAITEMENT D'UNE PRISE EXCESSIVE D'OPIOÏDES (COMPOSITIONS AND METHODS FOR THE TREATMENT OF OPIOID OVERDOSE)
World Intellectual Property Organization (WIPO)	2018093666
Russian Federation	2769397	КОМПОЗИЦИИ И СПОСОБЫ ЛЕЧЕНИЯ ПЕРЕДОЗИРОВКИ ОПИОИДАМИ (COMPOSITIONS AND METHODS OF TREATING OPIOID OVERDOSE)
China	110139651	用于治疗阿片样物质过量的组合物和方法 (COMPOSITIONS AND METHODS FOR THE TREATMENT OF OPIOID OVERDOSE)