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Cerilliant
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Queensland Health
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Generated: April 20, 2018

DrugPatentWatch Database Preview

NALOXONE Drug Profile

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When do Naloxone patents expire, and what generic alternatives are available?

Naloxone is a drug marketed by West-ward Pharms Int, Wyeth Ayerst, Abraxis Pharm, Akorn, Astrazeneca, Eurohlth Intl Sarl, Hospira, Igi Labs Inc, Intl Medication, Marsam Pharms Llc, Mylan Institutional, Smith And Nephew, Solopak, Somerset Theraps Llc, Watson Labs, Gavis Pharms, and Sun Pharm Inds Ltd. and is included in fifty-six NDAs.

The generic ingredient in NALOXONE is naloxone hydrochloride; pentazocine hydrochloride. There are twelve drug master file entries for this compound. Seven suppliers are listed for this compound. Additional details are available on the naloxone hydrochloride; pentazocine hydrochloride profile page.
Drug patent expirations by year for NALOXONE
Pharmacology for NALOXONE
Drug ClassOpioid Antagonist
Mechanism of ActionOpioid Antagonists
Synonyms for NALOXONE
(-)-N-allyl-14-hydroxynordihydroxymorphinan-6-one
(-)-Naloxone
(1S,5R,13R,17S)-10,17-dihydroxy-4-(prop-2-en-1-yl)-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10-trien-14-one
(1S,5R,13R,17S)-10,17-dihydroxy-4-(prop-2-en-1-yl)-12-oxa-4-azapentacyclo[9.6.1.0;{1,13}.0;{5,17}.0;{7,18}]octadeca-7(18),8,10-trien-14-one
(1S,5R,13R,17S)-10,17-DIHYDROXY-4-(PROP-2-EN-1-YL)-12-OXA-4-AZAPENTACYCLO[9.6.1.0(1),(1)(3).0?,(1)?.0?,(1)?]OCTADECA-7(18),8,10-TRIEN-14-ONE
(4R,4aS,7aR,12bS)-3-allyl-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride
(4R,4aS,7aR,12bS)-4a,9-bis(oxidanyl)-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride
(4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride
(5alpha)-3,14-dihydroxy-17-prop-2-en-1-yl-4,5-epoxymorphinan-6-one
(5alpha)-4,5-Epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-one
(naloxone) 4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one
(naloxone)4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one
(naloxone)4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one
[17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydroxymorphinan-6-one
[3H]naloxone
[N-allyl-2,3-3H]naloxone
1-N-Allyl-14-hydroxynordihydromorphinone
1-N-Allyl-7,8-dihydro-14-hydroxynormorphinone
12-Allyl-7,7a,8,9-tetrahydro-3,7a-dihydroxy-4aH-8,9c-iminoethanophenanthro(4,5-bcd)furanone
12-Allyl-7,7a,8,9-tetrahydro-3,7a-dihydroxy-4aH-8,9c-iminoethanophenanthro[4,5-bcd]furan-5(6H)-one
17-allyl-3,14-dihydroxy-4,5alpha-epoxymorphinan-6-one
17-Allyl-4,5-alpha-epoxy-3,14-dihydroxymorphinan-6-one
17-Allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one
3,14-dihydroxy-17-(prop-2-en-1-yl)-4,5alpha-epoxymorphinan-6-one
357-08-4 (hydrochloride)
36B82AMQ7N
4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one
4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one (naloxone)
4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one( Naloxone)
4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(Naxolone)
4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one
4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(naloxone)C2H2O4
465-65-6
465N656
4aH-8,5-bcd]furan-5(6H)-one, N-allyl-7,7a,8,9-tetrahydro-3,7a-dihydroxy-
AJ-20933
AK113003
AKOS016009988
AN-45114
API0003490
BDBM50000788
BDBM54795
BIDD:GT0110
BPBio1_000136
BRD-K67511046-003-03-7
BRN 1089071
BSPBio_000122
C07252
CAS-465-65-6
CHEBI:7459
CHEMBL80
cid_5464092
D08249
D0RN5A
D0X3FX
DB01183
DBL Naloxone
DBL Naloxone (TN)
DSSTox_CID_3349
DSSTox_GSID_23349
DSSTox_RID_76986
DTXSID8023349
EINECS 207-365-7
EN 1530 base
EN 1530base
Evzio
GTPL1638
GTPL1676
HMS2090F20
HSDB 3279
KB-297992
l-N-Allyl-14-hydroxynordihydromorphinone
l-N-Allyl-7,8-dihydro-14-hydroxynormorphinone
l-Naloxone
LS-187184
LS-92141
MCULE-1335589007
MLS000069540
MLS000736771
Morphinan-6-one, 17-allyl-4,5alpha-epoxy-3,14-dihydroxy-
Morphinan-6-one, 17-allyl-4,5alpha-epoxy-3,14-dihydroxy- (8CI)
Morphinan-6-one, 17-allyl-4,5alpha-epoxy-3,14-dihydroxy-(8CI)
Morphinan-6-one, 4,5-alpha-epoxy-3,14-dihydroxy-17-(2-propenyl)-
Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)-, (5alpha)-
Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)-, (5alpha)- (9CI)
Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)-, (5alpha)-(9CI)
Morphinan-6-one, 4,5alpha-epoxy-3,14-dihydroxy-17-(2-propenyl)-
Morphinan-6-one,4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)-,(5|A)-
Morphinan-6-one,5-epoxy-3,14-dihydroxy-17-(2-propenyl)-, (5.alpha.)-
Morphinan-6-one,5.alpha.-epoxy-3,14-dihydroxy-
Morphinan-6-one,5.alpha.-epoxy-3,14-dihydroxy-17-(2-propenyl)-
N-Allyl-4,5alpha-epoxy-3,14-dihydroxy-6-morphinanon
N-Allyl-noroxymorphone
n-Allylnoroxymorphone
Nalone
Nalone (TN)
Nalossone
Nalossone [DCIT]
Naloxona
Naloxona [INN-Spanish]
Naloxone (INN)
Naloxone [INN:BAN]
Naloxone HCl
Naloxone Hydrobromide
naloxone hydrochloride hydrate
Naloxone Nasal Spray
Naloxone solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material
Naloxonum
Naloxonum [INN-Latin]
Narcan
Narcan (TN)
Narcanti
Narcanti (TN)
Narcon
NCGC00024674-02
NCGC00024674-03
NCGC00162267-02
NCGC00274058-01
Normorphinone, N-allyl-7,8-dihydro-14-hydroxy-, (-)-
Normorphinone, N-allyl-dihydro-14-hydroxy-
NSC 70413
NSC-70413
NSC70413
O940
PDSP2_001520
PL006225
Prestwick0_000111
Prestwick1_000111
Prestwick2_000111
Prestwick3_000111
SCHEMBL34284
SMP1_000205
SMR000058766
SPBio_002061
STOCK1N-69923
Tox21_112006
Tox21_112006_1
UNII-36B82AMQ7N
UZHSEJADLWPNLE-GRGSLBFTSA-N
ZINC389747

US Patents and Regulatory Information for NALOXONE

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Intl Medication NALOXONE HYDROCHLORIDE naloxone hydrochloride INJECTABLE;INJECTION 072076-001 Mar 24, 1988 RX No Yes ➤ Sign Up ➤ Sign Up ➤ Sign Up
Igi Labs Inc NALOXONE HYDROCHLORIDE naloxone hydrochloride INJECTABLE;INJECTION 072087-001 Apr 11, 1989 DISCN No No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Solopak NALOXONE HYDROCHLORIDE naloxone hydrochloride INJECTABLE;INJECTION 071672-001 Nov 17, 1987 DISCN No No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Mylan Institutional NALOXONE HYDROCHLORIDE naloxone hydrochloride INJECTABLE;INJECTION 205014-001 Jun 29, 2016 AP RX No No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration

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