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Last Updated: December 7, 2019

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MODERIL Drug Profile

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Which patents cover Moderil, and what generic alternatives are available?

Moderil is a drug marketed by Pfizer and is included in one NDA.

The generic ingredient in MODERIL is rescinnamine. There is one drug master file entry for this compound. Additional details are available on the rescinnamine profile page.

Summary for MODERIL
Drug patent expirations by year for MODERIL
Synonyms for MODERIL
11,17-Dimethoxy-18-[[1-oxo-3-3,4,5-trimethoxyphenyl)-2-propenyl]oxy]-3,20-yohimban-16-carboxylic acid methyl ester
11,17alpha-Dimethoxy-18beta-((1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl)oxy)-3beta,20alpha-yohimban-16beta-carboxylic acid methyl ester
15676-43-4
15676-44-5
24815-24-5
25460-29-1
28821-79-6
3-beta,20-alpha-Yohimban-16-beta-carboxylic acid, 18-beta-hydroxy-11,17-alpha-dimethoxy-, methyl ester, 3,4,5-trimethoxycinnamate (ester)
3-beta,20-alpha-Yohimban-16-beta-carboxylic acid, 18-beta-hydroxy-11,17-alpha-dimethoxy-,methyl ester, 3,4,5-trimethoxycinnamate (ester)
3,4,5-Trimethoxycinnamic acid, methyl reserpate
3,4,5-Trimethoxycinnamoyl methyl reserpate
3,4,5-Trimethylcinnamic acid, ester with methyl reserpate
3,4,5-Trimethylcinnamoyl methyl reserpate
3,5-Trimethoxycinnamic acid, methyl reserpate
3,5-Trimethoxycinnamoyl methyl reserpate
3.beta., 18.beta.-hydroxy-11,17.alpha.-dimethoxy-, methyl ester, 3,4,5-trimethoxycinnamate (ester)
3beta,20alpha-Yohimban-16beta-carboxylic acid, 18beta-hydroxy-11,17alpha-dimethoxy-, methyl ester, 3,4,5-trimethoxycinnamate (ester)
3beta,20alpha-Yohimban-16beta-carboxylic acid, 18beta-hydroxy-11,17alpha-dimethoxy-, methyl ester, 3,4,5-trimethoxycinnamate (ester), (E)-
4-25-00-01323 (Beilstein Handbook Reference)
412909-15-0
522-78-1
84-34-4
ACon1_002115
AI3-52763
Anaprel
Apolon
Apoterin
Benz[g]indolo[2, 1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-3-hydroxy-2,11-dimethoxy-, methyl ester, 3,4,5-trimethoxycinnamate
BPBio1_000392
BRD-K52930707-001-02-2
BRD-K52930707-001-04-8
BRN 0075328
BSPBio_000356
C06540
C35H42N2O9
Cartric
CCRIS 4711
CHEBI:28572
CHEBI:92923
CHEMBL1668
Cinamine
Cinatabs
Cinnaloid
Cinnasil
D00198
EINECS 246-471-8
GTPL7098
HMS1569B18
HMS2096B18
HMS2234E08
HSDB 2176
LS-1060
MEGxp0_001952
methyl (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
methyl (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-{[3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxy}-3,13-diazapentacyclo[11.8.0.0;{2,10}.0;{4,9}.0;{15,20}]henicosa-2(10),4,6,8-tetraene-19-carboxylate
methyl (3beta,16beta,17alpha,18beta,20alpha)-11,17-dimethoxy-18-({(2E)-3-[3,4,5-tris(methyloxy)phenyl]prop-2-enoyl}oxy)yohimban-16-carboxylate
methyl 11,17alpha-dimethoxy-18beta-{[(2E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxy}-3beta,20alpha-yohimban-16beta-carboxylate
Methyl 18-O-(3,4,5-trimethoxycinnamoyl)reserpate
Methyl 18beta-hydroxy-11,17alpha-dimethoxy-3beta,20alpha-yohimban-16beta-carboxylate
Methyl 1alpha,2beta,3alpha,4,4aalpha,5,7,8,13,13bbeta,14,14aalpha-dodecahydro-2alpha,11-dimethoxy-3beta-(3,4,5-trimethoxycinnamoyloxy)benz(g)indolo(2,3-a)quinolizine-1beta-carboxylate
Methyl reserpate 3,4,5-trimethoxycinnamic acid ester
Methyl trimethoxycinnamoylreserpate
MLS002153878
MolPort-001-742-634
NCGC00179585-04
NCGC00179585-04_C35H42N2O9_Cinnaloid
Normorescina
NSC 15628
NSC-15628
NSC15628
O-(3,4,5-Trimethoxy-trans-cinnamoyl) methyl reserpate
Paresinan
Prestwick_558
Prestwick2_000568
Prestwick3_000568
Q6W1F7DJ2D
Raupyrol
Raurescin
Raurescine
Recinnamine
Recitensina
Rescaloid
Rescamin
Rescidan
Rescin
Rescinamina
Rescinamina [INN-Spanish]
Rescinnamin
Rescinnamina
Rescinnamina [DCIT]
rescinnamine
Rescinnamine (JAN/INN)
Rescinnamine (VAN)
Rescinnamine [BAN:INN:JAN]
Rescinnamine [INN:BAN:JAN:NF]
Rescinnaminum
Rescinnaminum [INN-Latin]
Rescinpal
Rescisan
Rescitens
Resealoid
Resepinine (C35 alkaloid)
Reserpic acid methyl ester 3,4,5-trimethoxycinnamate
Reserpinene
Reserpinin
Reserpinine
Reserpinine (C35 alkaloid)
Reserpinine (VAN)
Resipal
Reskinnamin
Rozex
SCHEMBL181966
Scinnamina
SMR001233232
Tenamine
Trimethoxy cinnamoyl reserpate de methyl
Trimethoxy cinnamoyl reserpate de methyl [French]
Trimethoxycinnamoyl methyl reserpate
Tsuruselpi S
Tsuruselpi S (TN)
Tuareg
UNII-Q6W1F7DJ2D
Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-(((2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl)oxy)-, methyl ester, (3beta,16beta,17alpha,18beta,20alpha)-
Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-((1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl)-oxy)-, methyl ester, (3beta,16beta,17alpha,18beta(E),20alpha)-
Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-((1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl)oxy)-, methyl ester, (3beta,16beta,17alpha,18beta,20alpha)-
Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-[[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl]oxy]-, methyl ester, (3b,16b,17a,18b,20a)-
Yohimban-16-carboxylic acid,17-dimethoxy-18-[[1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl]oxy]-, methyl ester, (3.beta.,16.beta.,17.alpha.,18.beta.,20.alpha.)-
Yohimban-16-carboxylicacid,11,17-dimethoxy-18-[[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]oxy]-,methyl ester, (3b,16b,17a,18b,20a)-
ZINC4097185

US Patents and Regulatory Information for MODERIL

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Pfizer MODERIL rescinnamine TABLET;ORAL 010686-003 Approved Prior to Jan 1, 1982 DISCN No No   Start Trial   Start Trial   Start Trial
Pfizer MODERIL rescinnamine TABLET;ORAL 010686-006 Approved Prior to Jan 1, 1982 DISCN No No   Start Trial   Start Trial   Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

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