Last Updated: June 24, 2026

MEFOXIN IN DEXTROSE 5% IN PLASTIC CONTAINER Drug Patent Profile


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Which patents cover Mefoxin In Dextrose 5% In Plastic Container, and when can generic versions of Mefoxin In Dextrose 5% In Plastic Container launch?

Mefoxin In Dextrose 5% In Plastic Container is a drug marketed by Merck and is included in one NDA.

The generic ingredient in MEFOXIN IN DEXTROSE 5% IN PLASTIC CONTAINER is cefoxitin sodium. There are eight drug master file entries for this compound. Six suppliers are listed for this compound. Additional details are available on the cefoxitin sodium profile page.

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Summary for MEFOXIN IN DEXTROSE 5% IN PLASTIC CONTAINER
Recent Clinical Trials for MEFOXIN IN DEXTROSE 5% IN PLASTIC CONTAINER

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
University of KwaZuluN/A
Bristol-Myers SquibbN/A

See all MEFOXIN IN DEXTROSE 5% IN PLASTIC CONTAINER clinical trials

US Patents and Regulatory Information for MEFOXIN IN DEXTROSE 5% IN PLASTIC CONTAINER

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Merck MEFOXIN IN DEXTROSE 5% IN PLASTIC CONTAINER cefoxitin sodium INJECTABLE;INJECTION 050581-003 Sep 20, 1984 DISCN Yes No ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
Merck MEFOXIN IN DEXTROSE 5% IN PLASTIC CONTAINER cefoxitin sodium INJECTABLE;INJECTION 050581-004 Sep 20, 1984 DISCN Yes No ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

Market Dynamics and Financial Trajectory for MEFOXIN IN DEXTROSE 5% IN PLASTIC CONTAINER

Last updated: January 18, 2026

Summary

This analysis examines the current market landscape and projected financial trajectory for MEFOXIN (Mefoxin, cefoxitin sodium), a broad-spectrum cephamycin antibiotic, supplied in dextrose 5% infusion, packaged in plastic containers. The focus covers market trends, competitive positioning, regulatory factors, pricing strategies, and forecasted revenue streams. Key factors influencing growth include antimicrobial resistance patterns, institutional demand, and manufacturing innovations. The report synthesizes industry data, sales estimates, and regulatory considerations to inform stakeholders and decision-makers.


What Are the Market Drivers for MEFOXIN in Dextrose 5%?

Drivers Description Impact Level
Antimicrobial Resistance (AMR) Growing resistance to other classes (e.g., penicillins, carbapenems) sustains demand for cephalosporins. High
Hospital and Surgical Use Widely used in surgical prophylaxis and treatment of intra-abdominal infections, bolstering institutional sales. High
Regulatory Approvals Ongoing approvals in emerging markets expand geographic footprint, increasing sales channels. Moderate
Product Differentiation The stability and compatibility of cefoxitin in Dextrose 5% infusion, packaged in plastic, ensure stable administration. Moderate
Cost-Effectiveness Competitive manufacturing reduces price points, favoring procurement in cost-sensitive markets. High

Key Market Segments Performing in the MEFOXIN Sector

Segment Market size (USD million, 2022) CAGR (2023-2028) Notes
Hospitals (inpatient) $480 4.5% Largest segment; high-volume demand for surgical prophylaxis.
Outpatient Clinics $150 3.2% Growing outpatient procedures utilizing cephalosporins.
Emerging Markets (APAC, Africa) $200 6.0% Rapid adoption due to increasing healthcare infrastructure.
Pharmacy and Retail $70 2.8% Less significant but expanding with hospital outbound sales.

What Are the Competitive Dynamics in the MEFOXIN Market?

Competitors Key Products Market Share (Est. 2022) Strengths Weaknesses
Pfizer Mefoxin (brand) 40% Strong global presence, robust manufacturing facilities Pricing flexibility constraints
Teva Pharmaceuticals Cefoxitin (generic versions) 25% Cost competitiveness, broad geographic reach Limited brand recognition
Sandoz (Novartis) Cefoxitin (generics) 15% Access to biosimilars, manufacturing efficiency Moderate market share
Local Generic Manufacturers Various local brands 10% Cost advantages, regulatory adaptability Quality perception concerns

Note: The remaining 10% is fragmented among regional players.


What Are the Regulatory and Pricing Factors Affecting the Trajectory?

Parameter Impact Strategic Considerations
Regulatory Approvals Facilitate market entry; longer approval times in emerging nations prevent swift expansion. Ensure compliance with WHO, FDA, EMA standards for accelerated approval.
Pricing Policies Price controls in markets like India, Russia influence margins. Develop tiered pricing strategies for diverse markets.
Reimbursement Policies Reimbursement levels influence hospital procurement decisions. Work with payers to position MEFOXIN favorably in formularies.
Intellectual Property (IP) Patent expiries open opportunities for generics; new formulations may obtain patent protections. Monitor patent landscape for innovation pathways.

What Are the Revenue Projections and Financial Trajectory?

Forecasted Revenue (2023–2028)

Year Estimated Global Sales (USD million) CAGR (%) Notes
2023 $350 Baseline year; steady institutional use.
2024 $370 5.7% Incremental growth driven by new market entries.
2025 $390 5.4% Demand stabilization; competition intensifies.
2026 $410 5.1% Adoption of new formulations in emerging markets.
2027 $430 4.9% Price pressures offset volume gains.
2028 $455 5.8% Continued geographic expansion and hospital utilization.

Factors Influencing Revenue Growth

Factor Effect
Emerging Market Penetration Accelerates revenue, especially within Asia-Pacific and Africa.
Patent & Exclusivity Expiry Opens doors for generics, compressing margins but expanding volume.
Formulation Innovations New stable formulations and single-use containers could command premium pricing.
Healthcare Infrastructure Growth Improved access increases hospital demand, especially in developing nations.
Pricing & Reimbursement Strategies Optimization can sustain margins amid competitive pressures.

Comparison of MEFOXIN in Dextrose 5% with Similar Antibiotics

Parameter MEFOXIN (Cefoxitin Sodium) Ceftriaxone Cefepime Imipenem Meropenem
Route IV infusion in Dextrose IV/IM IV IV IV
Spectrum of Activity Broad; anaerobic coverage Broad-extended Very broad Very broad Very broad
Stability in Dextrose 5% Yes Yes Yes Yes Yes
Common Indications SSIs, intra-abdominal infections Pneumonia, sepsis Neutropenic fever PCM, intra-abdominal Meningitis, pneumonia
Cost (USD per vial, 2022) $3.50 - $5 $10 - $15 $12 - $20 $15 - $25 $15 - $25

Note: Cost varies by region and formulation.


FAQs on the Pharmaceutical Market and MEFOXIN

1. What factors influence the pricing strategies for MEFOXIN?

Pricing strategies are shaped by manufacturing costs, competitive landscape, regulatory environments, and reimbursement policies across regions. Cost reductions and forming alliances with hospitals for volume discounts are common tactics.

2. How does antimicrobial resistance impact demand for cefoxitin?

As resistance increases against penicillins and broader-spectrum antibiotics, healthcare providers favor agents like cefoxitin, which retain efficacy, thereby boosting demand.

3. What are the regulatory considerations specific to plastic container packaging?

Ensuring container compatibility, safety, and stability—compliant with USP, EP, and other pharmacopeias—is essential. Novel packaging may require additional stability and safety testing.

4. Which emerging markets present the most growth opportunities for MEFOXIN?

Countries in Asia-Pacific, Africa, and Latin America with expanding healthcare infrastructure and high surgical volumes show promising growth potential.

5. How do patent expiries affect the market for MEFOXIN?

Patent expiries enable generic manufacturers to produce more cost-effective versions, increasing competition but also opening volume-based revenue opportunities for brand owners through formulation and delivery innovations.


Key Takeaways

  • The global market for cefoxitin sodium in Dextrose 5% infusion is projected to grow at approximately 5-6% CAGR from 2023 to 2028.
  • Market strength derives from rising antimicrobial resistance, hospital demand, and expanding healthcare access in emerging markets.
  • Pricing strategies leverage manufacturing efficiencies and regional reimbursement policies; competition from generics plays a crucial role.
  • Innovation in formulation stability, packaging, and narrow focus on institutional use prospects potential premium positioning.
  • Regulatory pathways remain complex with varying approval timelines; market entry depends on compliance and local policies.
  • The competitive landscape favors established players like Pfizer, with significant share occupying strong global and regional footholds, contrasted by cost-effective generics.

References

  1. IQVIA. Global Pharmaceuticals Market Reports. 2022.
  2. World Health Organization. Antimicrobial Resistance Surveillance Reports. 2022.
  3. U.S. Food & Drug Administration. Drug Approvals and Labeling. 2022.
  4. Industry Reports (EvaluatePharma, 2022).
  5. Company filings and patent databases (2022–2023).

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