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LOCOID Drug Profile
When do Locoid patents expire, and what generic alternatives are available?
Locoid is a drug marketed by Precision Dermat and Yamanouchi and is included in eight NDAs. There are two patents protecting this drug and two Paragraph IV challenges.
The generic ingredient in LOCOID is hydrocortisone butyrate. There are sixty-seven drug master file entries for this compound. Ten suppliers are listed for this compound. Additional details are available on the hydrocortisone butyrate profile page.
Summary for LOCOID
| US Patents: | 2 |
| Applicants: | 2 |
| NDAs: | 8 |
| Suppliers / Packagers: | 3 |
| Bulk Api Vendors: | 48 |
| Clinical Trials: | 4 |
| Patent Applications: | 2,910 |
| Formulation / Manufacturing: | see details |
| Drug Prices: | Drug price information for LOCOID |
| Drug Sales Revenues: | Drug sales revenues for LOCOID |
| Prior Art and Litigation Support | Order Prior Art and Litigation support for LOCOID |
| DailyMed Link: | LOCOID at DailyMed |
Pharmacology for LOCOID
| Drug Class | Corticosteroid |
| Mechanism of Action | Corticosteroid Hormone Receptor Agonists |
Synonyms for LOCOID
| (11beta)-11,21-Dihydroxy-17-(1-oxobutoxy)pregn-4-ene-3,20-dione |
| (1S,10S,11S,15S,17S,2R,14R)-17-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyl-5-ox otetracyclo[8.7.0.0<2,7>.0<11,15>]heptadec-6-en-14-yl butanoate |
| [(8S,9S,10R,11S,13S,14S,17R)-10,13-dimethyl-11-oxidanyl-17-(2-oxidanylethanoyl)-3-oxidanylidene-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] butanoate |
| [(8S,9S,10R,11S,13S,14S,17R)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] butanoate |
| 05RMF7YPWN |
| 11-beta,17-alpha,21-Trihydroxy-4-pregnene-3,20-dione 17-alpha-butyrate |
| 11|A,17,21-Trihydroxypregn-4-ene-3,20-dione 17-butyrate |
| 11beta,17,21-Trihydroxypregn-4-ene-3,20-dione 17-butyrate |
| 11beta,21-dihydroxy-17alpha-butyryloxy-4-pregnene-3,20-dione |
| 11beta,21-dihydroxy-3,20-dioxopregn-4-en-17-yl butanoate |
| 135467-84-4 |
| 13609-67-1 |
| 17-O-butyrylcortisol |
| 609H671 |
| A807026 |
| AC-492 |
| AC1L1AHF |
| AC1Q6OBN |
| AJ-47560 |
| AKOS015895443 |
| Alfason |
| AN-15773 |
| API0005043 |
| AX8134121 |
| BC214764 |
| BCP11925 |
| Bucort |
| butanoic acid [(8S,9S,10R,11S,13S,14S,17R)-11-hydroxy-17-(2-hydroxy-1-oxoethyl)-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] ester |
| Butyric acid hydrocortisone |
| CAS-13609-67-1 |
| CHEBI:31674 |
| CHEMBL1683 |
| Cortisol 17-butyrate |
| CORTISOL, 17-BUTYRATE |
| CS-4474 |
| CTK0H7965 |
| D01619 |
| DSSTox_CID_25896 |
| DSSTox_GSID_45896 |
| DSSTox_RID_81208 |
| DTXSID4045896 |
| EINECS 237-093-4 |
| Epitope ID:119710 |
| H-17-B |
| H.17B |
| HB(sub 17) |
| HMS2231B16 |
| HY-B0983 |
| Hycortate |
| Hydrocortisone 17-butyrate |
| hydrocortisone butyrate |
| Hydrocortisone Butyrate (Hydrocortisone 17-Butyrate) |
| Hydrocortisone butyrate (JP17/USP) |
| Hydrocortisone butyrate [USAN:BAN:JAN] |
| Hydrocortisone butyrate [USAN:USP:BAN:JAN] |
| Hydrocortisone butyrate, United States Pharmacopeia (USP) Reference Standard |
| Hydrocortisone-17-butyrate |
| Hydrocortisone-17alpha-butyrate |
| KB-277960 |
| Lacoid |
| Lacoidon |
| Laticort |
| locoid (TN) |
| LS-54996 |
| MFCD00083364 |
| MLS000028716 |
| MLS001076086 |
| MLS002207122 |
| MolPort-003-941-574 |
| NCGC00095037-01 |
| NCGC00274077-01 |
| Opera_ID_188 |
| Pregn-4-ene-3,20-dione, 11,21-dihydroxy-17-(1-oxobutoxy)-, (11-beta)- |
| Pregn-4-ene-3,20-dione, 11,21-dihydroxy-17-(1-oxobutoxy)-, (11beta)- |
| SCHEMBL4695 |
| SMR000058859 |
| ST075194 |
| Tox21_111397 |
| Tox21_111397_1 |
| UNII-05RMF7YPWN |
| W-108252 |
| ZINC3977794 |
US Patents and Regulatory Information for LOCOID
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Exclusivity Expiration |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Precision Dermat | LOCOID | hydrocortisone butyrate | CREAM;TOPICAL | 018514-001 | Mar 31, 1982 | AB1 | RX | Yes | Yes | ➤ Try a Free Trial | ➤ Try a Free Trial | ➤ Try a Free Trial | |||
| Precision Dermat | LOCOID | hydrocortisone butyrate | SOLUTION;TOPICAL | 019116-001 | Feb 25, 1987 | AT | RX | Yes | Yes | ➤ Try a Free Trial | ➤ Try a Free Trial | ➤ Try a Free Trial | |||
| Precision Dermat | LOCOID | hydrocortisone butyrate | LOTION;TOPICAL | 022076-001 | May 18, 2007 | AB | RX | Yes | Yes | ➤ Try a Free Trial | ➤ Try a Free Trial | Y | ➤ Try a Free Trial | ||
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Exclusivity Expiration |
Paragraph IV (Patent) Challenges for LOCOID
| Drugname | Dosage | Strength | RLD | Date |
|---|---|---|---|---|
| ➤ Subscribe | Lotion | 0.1% | ➤ Subscribe | ➤ Try a Free Trial |
| ➤ Subscribe | Cream | 0.1% | ➤ Subscribe | ➤ Try a Free Trial |
Premature patent expiration for: LOCOID
Expiration due to failure to pay maintenance fee
| Patent Number | Tradename | Expiration Date |
|---|---|---|
| ➤ Try a Free Trial | LOCOID | ➤ Try a Free Trial |
