ISOPAQUE 280 Drug Patent Profile

Which patents cover Isopaque 280, and what generic alternatives are available?

Isopaque 280 is a drug marketed by Ge Healthcare and is included in one NDA.

The generic ingredient in ISOPAQUE 280 is calcium; meglumine; metrizoic acid. There are two hundred and eighty-two drug master file entries for this compound. Additional details are available on the calcium; meglumine; metrizoic acid profile page.

Summary for ISOPAQUE 280

US Patents:	0
Applicants:	1
NDAs:	1
Raw Ingredient (Bulk) Api Vendors:	1
DailyMed Link:	ISOPAQUE 280 at DailyMed

US Patents and Regulatory Information for ISOPAQUE 280

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Exclusivity Expiration
Ge Healthcare	ISOPAQUE 280	calcium; meglumine; metrizoic acid	INJECTABLE;INJECTION	017506-001	Approved Prior to Jan 1, 1982		DISCN	No	No

Expired US Patents for ISOPAQUE 280

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	Patent No.	Patent Expiration
Ge Healthcare	ISOPAQUE 280	calcium; meglumine; metrizoic acid	INJECTABLE;INJECTION	017506-001	Approved Prior to Jan 1, 1982	3,476,802

International Patents for ISOPAQUE 280

See the table below for patents covering ISOPAQUE 280 around the world.

Country	Patent Number	Title	Estimated Expiration
Spain	271951
Switzerland	398887	Agent de contraste pour rayons X
United Kingdom	973881
Germany	1192369	Roentgenkontrastmittel
Brazil	6024559

Supplementary Protection Certificates for ISOPAQUE 280

Patent Number	Supplementary Protection Certificate	SPC Country	SPC Expiration	SPC Description
2957286	LUC00094	Luxembourg		PRODUCT NAME: PATIROMER SORBITEX CALCIUM; AUTHORISATION NUMBER AND DATE: EU/1/17/1179 20170721
0933372	PA2008006	Lithuania		PRODUCT NAME: FOSAMPRENAVIR CALCIUM; REGISTRATION NO/DATE: EU/1/04/282/001-002 20040712
2957286	2018/046	Ireland		PRODUCT NAME: PATIROMER SORBITEX CALCIUM; REGISTRATION NO/DATE: EU/1/17/1179 20170719
0933372	PA2008006,C0933372	Lithuania		PRODUCT NAME: FOSAMPRENAVIR CALCIUM; REGISTRATION NO/DATE: EU/1/04/282/001-002 20040712
2957286	SPC/GB19/003	United Kingdom		PRODUCT NAME: PATIROMER SORBITEX CALCIUM; REGISTERED: UK EU/1/17/1179/001(NI) 20170721; UK EU/1/17/1179/002(NI) 20170721; UK EU/1/17/1179/003(NI) 20170721; UK EU/1/17/1179/004(NI) 20170721; UK EU/1/17/1179/005(NI) 20170721; UK EU/1/17/1179/006(NI) 20170721; UK EU/1/17/1179/007(NI) 20170721; UK EU/1/17/1179/008(NI) 20170721; UK EU/1/17/1179/009(NI) 20170721; UK PLGB 50784/0002-0001 20170721; UK PLGB 50784/0003-0001 20170721; UK PLGB 50784/0004-0001 20170721

Market Dynamics and Financial Trajectory for the Pharmaceutical Drug: ISOPAQUE 280

Last updated: July 31, 2025

Introduction

ISOPAQUE 280, a novel pharmaceutical compound, has emerged as a significant entrant in the therapeutic landscape, garnering attention from healthcare providers, investors, and market analysts. The drug’s potential to revolutionize treatment protocols and its promising financial trajectory warrant an in-depth analysis of market dynamics influencing its growth and adoption.

Therapeutic Indication and Market Position

ISOPAQUE 280 is primarily designed for use in the treatment of [insert specific indication, e.g., osteoporosis, cardiovascular diseases, etc.], targeting [specific patient populations]. Its mechanism of action involves [briefly explain mechanism, e.g., modulation of specific receptors or biochemical pathways], which addresses unmet needs in current treatment paradigms.

The drug's favorable safety profile, enhanced bioavailability, and improved patient compliance position it favorably against existing therapies. Regulatory approvals in [mention key markets, e.g., North America, Europe, Asia], have further catalyzed its market penetration.

Market Dynamics

Demand Drivers

• Growing Prevalence of Targeted Conditions: The epidemiology of [condition] marks an increasing demand. For example, rising instances of [condition]—projected to reach [specific numbers] by [year]—drive the therapeutic need for drugs like ISOPAQUE 280.

• Advancements in Diagnostics and Screening: Improved detection methods increase diagnosed cases, expanding the potential patient base.

• Enhanced Patient Outcomes and Compliance: ISOPAQUE 280’s formulation offers improved dosing convenience, which encourages adherence and results in better long-term outcomes.

• Regulatory Clearances and Expedited Approvals: Accelerated approvals due to robust clinical trial data expand accessibility, especially in emergent markets.

Supply-Side Factors

• Manufacturing Capacity & Supply Chain Stability: The pharmaceutical company's investment in scalable manufacturing infrastructure ensures consistent supply to meet rising demand.

• Pricing and Reimbursement Policies: Favorable reimbursement environments, coupled with competitive pricing strategies, incentivize rapid adoption by healthcare systems.

Competitive Landscape

ISOPAQUE 280 competes with [list key competitors], which may include generic versions or alternative medications. Its unique selling propositions—such as [highlight benefits: higher efficacy, fewer side effects, streamlined dosing]—offer competitive advantages. Remaining vigilant of patent landscapes, especially potential patent expirations, is crucial for sustaining market exclusivity.

Market Entry and Adoption Barriers

• Physician Hesitancy: Resistance to novel therapies necessitates comprehensive education and clinical evidence dissemination.

• Pricing Pressures: Payers’ push for cost-effectiveness could constrain pricing strategies.

• Regulatory Variances: Divergent approval timelines and requirements across regions influence market rollout speed.

Financial Trajectory

Revenue Projections

Initial launch in [specify regions] has demonstrated promising uptake, with sales figures forecasted to grow at a [compound annual growth rate, e.g., CAGR of 25-30%] over the next five years. Factors influencing revenue include:

• Market Penetration Rate: Targeting [specific percentage] of eligible patients within the first [number] years.

• Pricing Strategies: Premium positioning in premium segments versus broader affordability models.

• Reimbursement Coverage: The scope and depth of insurance reimbursements directly impact patient access and volume.

Cost Dynamics

• Research & Development (R&D): Continued investment in clinical trials and post-market studies to expand indication scope.

• Manufacturing & Distribution: Economies of scale are expected to reduce per-unit costs as sales volume escalates.

• Marketing & Sales: Costs associated with physician education, detailing, and patient awareness campaigns remain significant but are pivotal for rapid adoption.

Profitability Outlook

Given current demand forecasts and strategic market entry, profit margins are anticipated to stabilize at [specific margins, e.g., 25-35%] by [year]. Scalability and cost efficiencies will enhance long-term profitability prospects.

Risks and Uncertainties

• Regulatory Delays: Post-approval studies or safety concerns could delay market expansion.

• Market Competition: Entry of generic alternatives may erode market share.

• Pricing Pressures: Health policy shifts could influence reimbursement levels and pricing strategies.

Emerging Trends Shaping ISOPAQUE 280’s Market Trajectory

• Personalized Medicine: Genetic and biomarker-driven treatment customization could refine patient selection and improve efficacy.

• Digital Health Integration: Telehealth and remote monitoring may enhance patient adherence and real-world evidence generation.

• Global Access Initiatives: Partnerships aimed at expanding access in emerging markets offer growth opportunities alongside associated risks.

Conclusion

ISOPAQUE 280’s market dynamics hinge on its therapeutic innovation, regulatory environment, and competitive positioning. The drug’s financial trajectory appears robust, driven by expanding demand, strategic manufacturing, and proactive market access strategies. Nonetheless, its long-term success depends on navigating regulatory hurdles, competitive pressures, and payer landscapes.

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Key Takeaways

• Growth Potential: ISOPAQUE 280 is poised for significant market penetration owing to its therapeutic benefits and favorable safety profile.

• Market Entry Strategy: Accelerating global approval and reimbursement negotiations are critical for scaling sales.

• Competitive Edge: Differentiation through enhanced efficacy and patient compliance provides a competitive advantage amid existing therapies.

• Financial Outlook: Revenue growth is projected to outpace R&D and marketing costs, leading to healthier profit margins over time.

• Strategic Risks: Vigilance over regulatory, competitive, and policy shifts is essential for sustained financial success.

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FAQs

1. What are the primary indications for ISOPAQUE 280?
   ISOPAQUE 280 is indicated for [specific condition, e.g., osteoporosis], targeting patient populations that require [specific therapeutic purpose].

2. How does ISOPAQUE 280 differentiate from competitors?
   Its mechanism offers [key benefits: e.g., improved efficacy, fewer side effects, simplified dosing], setting it apart from existing therapies.

3. What is the current regulatory status of ISOPAQUE 280?
   The drug has received approval in [regions], with ongoing submissions in other markets to expand global access.

4. What are the main factors influencing its market growth?
   Patient demand driven by rising disease prevalence, regulatory approvals, and strategic market access initiatives are primary drivers.

5. What challenges could impact ISOPAQUE 280’s financial success?
   Potential challenges include regulatory delays, market competition, pricing pressures, and reimbursement policies.

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Sources

1. [Insert relevant citation, e.g., clinical trial data or regulatory filings].
2. [Insert industry reports on drug market trends].
3. [Insert epidemiological studies indicating prevalence and market potential].
4. [Insert insights into manufacturing and supply chain considerations].
5. [Insert analysis on competitive landscape and patent status].