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Last Updated: October 15, 2019

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IOPIDINE Drug Profile

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Which patents cover Iopidine, and what generic alternatives are available?

Iopidine is a drug marketed by Novartis Pharms Corp and is included in two NDAs.

The generic ingredient in IOPIDINE is apraclonidine hydrochloride. There are three drug master file entries for this compound. Three suppliers are listed for this compound. Additional details are available on the apraclonidine hydrochloride profile page.

Drug patent expirations by year for IOPIDINE
Drug Prices for IOPIDINE

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Recent Litigation for IOPIDINE

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District Court Litigation
Case NameDate
Allergan Inc. v. Alcon Inc.2004-08-24

See all IOPIDINE litigation

Pharmacology for IOPIDINE
Synonyms for IOPIDINE
1,4-Benzenediamine, 2,6-dichloro-N'-(4,5-dihydro-1H-imidazol-2-yl)-
1,4-Benzenediamine, 2,6-dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)-
2-((4-Amino-2,6-dichlorophenyl)imino)imidazolidine
2-(4-amino-2,6-dichloro)phenyliminoimidazolidine
2-(4-Amino-2,6-dichlorophenylamino)-2-imidazoline
2-(4-amino-2,6-dichlorophenylimino) imidazolidine
2-(4-amino-2,6-dichlorophenylimino)imidazolidine
2,6-dichloro-1-N-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine
2,6-dichloro-N-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine
2,6-Dichloro-N-imidazolidin-2-ylidene-benzene-1,4-diamine
2,6-Dichloro-N-imidazolidin-2-ylidene-benzene-1,4-diamine (p-aminoclonidine)
2,6-Dichloro-N-imidazolidin-2-ylidene-benzene-1,4-diamine(p-Aminoclonidine)
2,6-dichloro-N(1)-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine
2,6-Dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine
2,6-DICHLORO-N1-(IMIDAZOLIDIN-2-YLIDENE)BENZENE-1,4-DIAMINE
4-Aminoclonidine
66711-21-5
711A215
843CEN85DI
AC-12697
AC1L1D6L
AJ-09624
AKOS016010355
AKOS025401361
AL-02145
ALO 2145
Aminoclonidine, p
AN-38453
Aplonidine
Apraclonidina
Apraclonidina [INN-Spanish]
apraclonidine
Apraclonidine (INN)
Apraclonidine [INN:BAN]
Apraclonidinum
Apraclonidinum [INN-Latin]
BDBM50021812
BDBM81926
C07668
C9H10Cl2N4
CAS_66711-21-5
CCG-204129
CHEBI:2788
CHEMBL647
D07461
DB00964
DTXSID1048415
FT-0602879
GTPL7117
IEJXVRYNEISIKR-UHFFFAOYSA-N
Iopidine (TN)
Iopidine Eye
K093
KB-226140
L000686
L013394
Lopac-A-0779
Lopac0_000033
LS-176536
NCGC00015033-01
NCGC00015033-02
NCGC00015033-03
NCGC00162050-01
NSC_51763
p-amino clonidine
p-aminoclonidine
P-AMINOCLONIDINE2,6-Dichloro-N-imidazolidin-2-ylidene-benzene-1,4-diamine
para-aminoclonidine
PDSP1_000790
PDSP2_000778
SCHEMBL34127
SMP1_000016
UNII-843CEN85DI
ZINC20231

US Patents and Regulatory Information for IOPIDINE

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Novartis Pharms Corp IOPIDINE apraclonidine hydrochloride SOLUTION/DROPS;OPHTHALMIC 020258-001 Jul 30, 1993 AT RX Yes Yes   See Pricing   See Pricing   See Pricing
Novartis Pharms Corp IOPIDINE apraclonidine hydrochloride SOLUTION/DROPS;OPHTHALMIC 019779-001 Dec 31, 1987 RX Yes Yes   See Pricing   See Pricing   See Pricing
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

Expired US Patents for IOPIDINE

Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration
Novartis Pharms Corp IOPIDINE apraclonidine hydrochloride SOLUTION/DROPS;OPHTHALMIC 020258-001 Jul 30, 1993   See Pricing   See Pricing
Novartis Pharms Corp IOPIDINE apraclonidine hydrochloride SOLUTION/DROPS;OPHTHALMIC 019779-001 Dec 31, 1987   See Pricing   See Pricing
Novartis Pharms Corp IOPIDINE apraclonidine hydrochloride SOLUTION/DROPS;OPHTHALMIC 019779-001 Dec 31, 1987   See Pricing   See Pricing
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >Patent No. >Patent Expiration

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Serving leading biopharmaceutical companies globally:

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Moodys
McKesson
Boehringer Ingelheim
Baxter

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