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Generated: April 20, 2018

DrugPatentWatch Database Preview

IFEX Drug Profile

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When do Ifex patents expire, and what generic alternatives are available?

Ifex is a drug marketed by Baxter Hlthcare and is included in one NDA.

The generic ingredient in IFEX is ifosfamide; mesna. There are five drug master file entries for this compound. One supplier is listed for this compound. Additional details are available on the ifosfamide; mesna profile page.
Drug patent expirations by year for IFEX
Pharmacology for IFEX
Drug ClassAlkylating Drug
Mechanism of ActionAlkylating Activity
Synonyms for IFEX
(+-)-Ifosfamid
(+-)-Ifosphamide
(+-)-Tetrahydro-N,3-bis(2-chloroethyl)-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
(2S)-3-(2-chloroethyl)-2-[(2-chloroethyl)amino]-1,3,2|E5-oxazaphosphinan-2-one
(D,L)-Ifosfamide
(R,S)-Ifosphamide
(R,S)-N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
(R)-Ifosfamide
(S)-Ifosfamide
{3-(2-Chloroethyl)-2-[(2-
{3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,3,} 2-oxazaphosphorine oxide
1,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide
1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide
1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide
2,3-(N,N(sup 1)-Bis(2-chloroethyl)diamido)-1,3,2-oxazaphosphoridinoxyd
2,3-N,N(sup 1)-Bis(2-chloroethyl)diamido-1,3,2-oxazaphosphoridinoxy-
2,3-N,N(sup 1)-Bis(2-chloroethyl)diamido-1,3,2-oxazaphosphoridinoxyd
2,N(sup 1)-Bis(2-chloroethyl)diamido-1,3,2-oxazaphosphoridinoxy-
2,N(sup 1)-Bis(2-chloroethyl)diamido-1,3,2-oxazaphosphoridinoxyd
2H-1,2-Oxazaphosphorin-2-amine, N,3-bis(2-chloroethyl)tetrahydro-, 2-oxide
2H-1,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide
2H-1,3,2-Oxazaphosphorin-2-amine, N,3-bis( 2-chloroethyl)tetrahydro-, 2-oxide
2H-1,3,2-Oxazaphosphorin-2-amine, N,3-bis(2-chloroethyl)tetrahydro-, 2-oxide
2H-1,3,2-Oxazaphosphorin-2-amine, tetrahydro-N,3-bis(2-chloroethyl)-, 2-oxide, (+-)-
2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide
2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide (8CI)
2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide
3-(2-chloroethyl)-2-((2-chloroethyl)amino)-1,3,2-oxazaphosphinane 2-oxide
3-(2-Chloroethyl)-2-((2-chloroethyl)amino)perhydro-2H-1,3,2-oxazaphosphorine oxide
3-(2-Chloroethyl)-2-((2-chloroethyl)amino)perhydro-2H-1,3,2-oxazaphosphorineoxide
3-(2-Chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide
3-(2-Chloroethyl)-2-(2-chloroethylamino)tetrahydro-2H-1,3,2-oxazaphosphorin-2-one
3-(2-chloroethyl)-2-[(2-chloroethyl)amino]-1,3,2$l;{5}-oxazaphosphinan-2-one
3-(2-chloroethyl)-2-[(2-chloroethyl)amino]-1,3,2lambda5-oxazaphosphinan-2-one
3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,2-oxazaphosphorine oxide
3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,2-oxazaphosphorineoxide
3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,3,2-oxazaphosphorine oxide
3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,3,2-oxazaphosphorineoxide
3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,2-oxazaphosphorine 2-oxide
3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2- oxide
3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide
3,} 2-oxazaphosphorine oxide
33899-EP2275420A1
33899-EP2295055A2
33899-EP2295416A2
33899-EP2298748A2
33899-EP2298764A1
33899-EP2298765A1
33899-EP2305642A2
33899-EP2311453A1
36341-88-5
3778-73-2
778I732
84711-20-6
A 4942
AB0008491
AB00513932
AB00513932_09
AB00513932_10
AB00513932-06
AB00513932-07
AB00513932-08
AB02316
AB2000039
AC-2113
AC1L1GHW
ACM1189701130
AKOS005711213
Ambap3778-73-2
AN-6958
API0002976
AS-10978
ASTA Z 4942
BBL028071
BDBM189358
BPBio1_000865
BRD-A67097164-001-11-2
BRN 0611835
BSPBio_000785
C-16296
C07047
C7H15Cl2N2O2P
CAS-3778-73-2
CC-29468
CCG-213464
CCRIS 352
CHEBI:5864
CHEMBL1024
CI0037
CS-1424
CTK8E8347
Cyfos
D00343
D02TLO
DB01181
dexifosfamide
DR000765
DSSTox_CID_760
DSSTox_GSID_20760
DSSTox_RID_75775
DTXSID7020760
EINECS 223-237-3
FT-0603650
GTPL7201
HE300382
HE339529
HMS1570H07
HMS2090M12
HMS2093N07
HMS2097H07
HMS2232O10
HMS3374B08
HMS3654B15
Holoxan
Holoxan 1000
HOMGKSMUEGBAAB-UHFFFAOYSA-N
HSDB 7023
HY-17419
I-Phosphamide
I06-0494
IFEX (TN)
Ifex (TN) (Bristol Meyers)
ifomide
Ifosfamid
Ifosfamid A
Ifosfamida
Ifosfamida [INN-Spanish]
ifosfamide
Ifosfamide (JAN/USP/INN)
Ifosfamide [USAN:INN:BAN:JAN]
Ifosfamide [USAN:USP:INN:BAN:JAN]
Ifosfamide Sterile
Ifosfamide, >=98%
Ifosfamide, analytical reference material
Ifosfamide, British Pharmacopoeia (BP) Reference Standard
Ifosfamide, European Pharmacopoeia (EP) Reference Standard
Ifosfamide, United States Pharmacopeia (USP) Reference Standard
Ifosfamidum
Ifosfamidum [INN-Latin]
ifosfomide
Ifosphamide
Ifsofamide
Iphosphamid
Iphosphamid(e)
Iphosphamide
Iso Endoxan
Iso-Endoxan
Isoendoxan
Isofosfamide
Isophosphamide
isosfamide
J10093
KB-333868
KS-00000YBW
KSC948G4P
LS-102
LS-99799
M-1494
MCULE-1480299331
MFCD00057374
Mitoxana
Mitoxana (TN)
Mitoxana, Ifex, Ifosfamide
Mitoxana;Ifex
MJF 9325
MJF-9325
MLS002154021
MolPort-003-666-704
N-(2-Chloraethyl)-N'-(2-chloraethyl)-N',O-propylen-phosphorsaureester-diamid
N-(2-Chloraethyl)-N'-(2-chloraethyl)-N',O-propylen-phosphorsaureester-diamid [German]
N-(2-Chloroethyl)-N-(3-(2-chloroethyl)-2-oxido-1,3,2-oxazaphosphinan-2-yl)amine
N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylen ephosphoric acid diamide
N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylene phosphoric acid ester diamide
N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylenephosphoric acid diamide
N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylenephosphoric acid ester diamide
N,3-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
N,3-bis(2-chloroethyl)-2-oxo-1,3,2?^{5}-oxazaphosphinan-2-amine
N,3-bis(2-chloroethyl)-2-oxo-1,3,2$l^{5}-oxazaphosphinan-2-amine
N,3-bis(2-chloroethyl)-2-oxo-1,3,2$l;{5}-oxazaphosphinan-2-amine
N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphinan-2-amine 2-oxide #
N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
N,N-Bis(beta-chloroethyl)-amino-N',O-propylene-phosphoric acid ester diamide
Naxamide
NCGC00016639-01
NCGC00179435-01
NCGC00179435-02
NCGC00179435-03
NCGC00179435-06
NCGC00179435-07
NCGC00256413-01
NCGC00259364-01
NCI-C01638
NCI60_000233
NPFAPI-04
NSC 109724
NSC-109,724
NSC-109724
NSC-759154
NSC109724
NSC759154
Pharmakon1600-01505480
Prestwick0_000833
Prestwick1_000833
Prestwick2_000833
Prestwick3_000833
Q-101874
s1302
SBI-0206804.P001
SC-12120
SCHEMBL4885
SMR001233348
SPBio_002706
SR-05000002022
SR-05000002022-5
STL058690
TA-01010
Tox21_110539
Tox21_110539_1
Tox21_201815
Tox21_302775
UNII-UM20QQM95Y component HOMGKSMUEGBAAB-AWEZNQCLSA-N
WLN: T6NPOTJ AM2G BO B2G
Z 4942
Z-4942
Z4942

US Patents and Regulatory Information for IFEX

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Baxter Hlthcare IFEX ifosfamide INJECTABLE;INJECTION 019763-001 Dec 30, 1988 AP RX Yes No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Baxter Hlthcare IFEX/MESNEX KIT ifosfamide; mesna INJECTABLE;INJECTION 019763-004 Oct 10, 1992 DISCN No No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Baxter Hlthcare IFEX ifosfamide INJECTABLE;INJECTION 019763-002 Dec 30, 1988 AP RX Yes No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Baxter Hlthcare IFEX/MESNEX KIT ifosfamide; mesna INJECTABLE;INJECTION 019763-003 Oct 10, 1992 DISCN No No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration

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Expired US Patents for IFEX

Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration
Baxter Hlthcare IFEX ifosfamide INJECTABLE;INJECTION 019763-002 Dec 30, 1988 ➤ Sign Up ➤ Sign Up
Baxter Hlthcare IFEX ifosfamide INJECTABLE;INJECTION 019763-002 Dec 30, 1988 ➤ Sign Up ➤ Sign Up
Baxter Hlthcare IFEX ifosfamide INJECTABLE;INJECTION 019763-001 Dec 30, 1988 ➤ Sign Up ➤ Sign Up
Baxter Hlthcare IFEX ifosfamide INJECTABLE;INJECTION 019763-001 Dec 30, 1988 ➤ Sign Up ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration

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Deloitte
Johnson and Johnson
Federal Trade Commission
Chubb
Queensland Health
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McKesson

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