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Baxter
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Mallinckrodt
Harvard Business School

Last Updated: November 11, 2019

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GIAPREZA Drug Profile

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Which patents cover Giapreza, and when can generic versions of Giapreza launch?

Giapreza is a drug marketed by La Jolla Pharma and is included in one NDA. There are five patents protecting this drug.

This drug has eleven patent family members in eleven countries.

The generic ingredient in GIAPREZA is angiotensin ii acetate. There are five drug master file entries for this compound. One supplier is listed for this compound. Additional details are available on the angiotensin ii acetate profile page.

Drug patent expirations by year for GIAPREZA
Drug Prices for GIAPREZA

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Generic Entry Opportunity Date for GIAPREZA
Generic Entry Date for GIAPREZA*:
Constraining patent/regulatory exclusivity:
NEW CHEMICAL ENTITY
NDA:
Dosage:
SOLUTION;IV (INFUSION)

*The generic entry opportunity date is the latter of the last compound-claiming patent and the last regulatory exclusivity protection. Many factors can influence early or later generic entry. This date is provided as a rough estimate of generic entry potential and should not be used as an independent source.

Recent Clinical Trials for GIAPREZA

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
University of California, Los AngelesEarly Phase 1
La Jolla Pharmaceutical CompanyPhase 1
Wake Forest University Health SciencesPhase 1

See all GIAPREZA clinical trials

Pharmacology for GIAPREZA
Drug ClassVasoconstrictor
Physiological EffectVasoconstriction
Synonyms for GIAPREZA
1-8-Angiotensin I
1-L-Aspasaginyl-5-L-valyl angiotensin octapeptide
11128-99-7
15963-93-6
3773-26-0
4474-91-3
5-Isoleucine-angiotensin II
5-L-Isoleucineangiotensin II
AC1L58RS
AK115685
AKOS016010178
Alanine, N-(1-(N-(N-(N-(N-(N2-L-alpha-aspartyl-L-arginyl)-L-valyl)-L-tyrosyl)-L-isoleucyl)-L-histidyl)-L-prolyl)-3-phenyl-, L-
Ang II
Angiotensin 2
ANGIOTENSIN II
Angiotensin II (9CI)
Angiotensin II (human type) (JAN)
Angiotensin II (human)
Angiotensin II (mouse)
Angiotensin II (rat)
Angiotensin II (USAN)
Angiotensin ii [INN:JAN]
Angiotensin II human
ANGIOTENSIN II-HUMAN
Angiotensin II, 5-L-isoleucine-
Angiotensin II, human
Angiotensin II, ile(5)-
Angiotensin II, mass spec standard
Asp-Arg-Val-Tyr-Ile-His-Pro-Phe
Asp1-Arg2-Val3-Tyr4-Ile5-His6-Pro7-Phe8
BDBM50228195
BDBM50236697
C02135
CHEBI:131170
CHEBI:2719
CHEMBL408403
CZGUSIXMZVURDU-JZXHSEFVSA-N
D02014
DB11842
Delivert (TN)
DTXSID30196288
FT-0688970
GTPL2504
Human angiotensin II
Ile(5)-angiotensin II
isoleucine(5)-angiotensin II
Isoleucine5-angiotensin II
L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine
L-phenylalanine, L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-
L-Phenylalanine, N-(1-(N-(N-(N-(N-(N2-L-alpha-aspartyl-L-arginyl)-L-valyl)-L-tyrosyl)-L-isoleucyl)-L-histidyl)-L-prolyl)-
M089EFU921
MolPort-023-276-011
MolPort-042-652-607
N-(1-(N-(N-(N-(N-(N(2)-L-alpha-aspartyl-L-arginyl)-L-valyl)-L-tyrosyl)-L-isoleucyl)-L-histidyl)-L-prolyl)-L-phenylalanine
NCGC00167130-01
ProteoMass(TM) Angiotensin II MALDI-MS Standard, vial of 10 nmol
ProteoMass™ Angiotensin II MALDI-MS Standard
SC-25843
SCHEMBL1189
SCHEMBL20502357
SCHEMBL9013957
ST2406631
ty-10721
UNII-M089EFU921
ZINC169676920

US Patents and Regulatory Information for GIAPREZA

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
La Jolla Pharma GIAPREZA angiotensin ii acetate SOLUTION;INTRAVENOUS 209360-001 Dec 21, 2017 RX Yes Yes   Start Trial   Start Trial   Start Trial
La Jolla Pharma GIAPREZA angiotensin ii acetate SOLUTION;INTRAVENOUS 209360-001 Dec 21, 2017 RX Yes Yes   Start Trial   Start Trial   Start Trial
La Jolla Pharma GIAPREZA angiotensin ii acetate SOLUTION;INTRAVENOUS 209360-001 Dec 21, 2017 RX Yes Yes   Start Trial   Start Trial   Start Trial
La Jolla Pharma GIAPREZA angiotensin ii acetate SOLUTION;INTRAVENOUS 209360-002 Dec 21, 2017 DISCN Yes No   Start Trial   Start Trial   Start Trial
La Jolla Pharma GIAPREZA angiotensin ii acetate SOLUTION;INTRAVENOUS 209360-002 Dec 21, 2017 DISCN Yes No   Start Trial   Start Trial   Start Trial
La Jolla Pharma GIAPREZA angiotensin ii acetate SOLUTION;INTRAVENOUS 209360-002 Dec 21, 2017 DISCN Yes No   Start Trial   Start Trial   Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

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Serving leading biopharmaceutical companies globally:

Johnson and Johnson
McKesson
Dow
Express Scripts
Merck
AstraZeneca

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.