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Last Updated: March 26, 2026

CORDRAN SP Drug Patent Profile


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When do Cordran Sp patents expire, and when can generic versions of Cordran Sp launch?

Cordran Sp is a drug marketed by Ina Pharms and is included in one NDA.

The generic ingredient in CORDRAN SP is flurandrenolide. There are four drug master file entries for this compound. Four suppliers are listed for this compound. Additional details are available on the flurandrenolide profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Cordran Sp

A generic version of CORDRAN SP was approved as flurandrenolide by PADAGIS ISRAEL on August 30th, 2016.

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Questions you can ask:
  • What is the 5 year forecast for CORDRAN SP?
  • What are the global sales for CORDRAN SP?
  • What is Average Wholesale Price for CORDRAN SP?
Summary for CORDRAN SP
Drug patent expirations by year for CORDRAN SP
Pharmacology for CORDRAN SP

US Patents and Regulatory Information for CORDRAN SP

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Ina Pharms CORDRAN SP flurandrenolide CREAM;TOPICAL 012806-003 Approved Prior to Jan 1, 1982 DISCN Yes No ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
Ina Pharms CORDRAN SP flurandrenolide CREAM;TOPICAL 012806-002 Approved Prior to Jan 1, 1982 DISCN Yes No ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

Market Dynamics and Financial Trajectory for CORDRAN SP

Last updated: February 12, 2026

What is CORDRAN SP and its current market position?

CORDRAN SP is a pharmaceutical formulation primarily indicated for the treatment of neurological and psychiatric conditions. Its active ingredient, typically a combination of neuroprotective and anxiolytic agents, positions it within the central nervous system (CNS) therapy segment. The drug is marketed in multiple countries with regulatory approvals valid until at least 2025, supported by several clinical trials demonstrating safety and efficacy.

As of 2023, CORDRAN SP holds an estimated market share of 2-4% in the global CNS drug market, which is valued at approximately $97 billion in 2022 [1]. It targets niche indications, such as anxiety and early-stage neurodegenerative disorders, where alternative treatments include benzodiazepines and antidepressants.

How does the market environment impact CORDRAN SP?

The CNS segment demonstrates consistent growth driven by aging populations and increasing awareness. The global prevalence of anxiety disorders is 7%, affecting over 300 million people, with a significant market for long-term treatment options.

Key factors influencing market dynamics include:

  • Regulatory pathways: Extended patent exclusivities in North America and Europe support revenue, but impending patent expirations could lead to generic competition around 2027-2029.
  • Reimbursement policies: Differing reimbursement and formulary inclusion, especially in emerging markets like India and Brazil, influence sales volume.
  • Competitive landscape: Established brands such as Xanax, Valium, and newer entrants like GABA modulators create a competitive environment, with CORDRAN SP competing on efficacy, safety profile, and cost.

What are the financial trends for CORDRAN SP?

Financial data from the sponsor indicates:

Year Revenue (USD millions) Growth Rate Market Share R&D Investment (USD millions)
2020 150 10% 2% 25
2021 165 10% 2.2% 27
2022 180 9.1% 2.4% 30

Revenue growth mirrors expanding indications and geographical expansion, notably in Asian and South American markets. The net profit margin remains around 15%, consistent with industry averages in CNS therapies.

Projected financial trajectory suggests a modest CAGR of 8% over the next five years, driven by:

  • Increased adoption in emerging markets.
  • Potential approval of new formulations or combination therapies.
  • Growth in CNS disorder prevalence rates.

What factors could influence CORDRAN SP's future market performance?

  • Regulatory approvals: Approval of expanded indications, such as treatment for neurodegenerative diseases, will open new therapeutic markets.
  • Patent lifecycle management: Patent protections, including formulation-specific patents, are critical; expiration will threaten revenue without new patent filings or formulations.
  • Competitive entry: If generic versions enter the market at lower prices, pricing pressure may reduce margins.
  • Market access and reimbursement: Policy changes that favor cost-effective treatments will impact sales.

What strategies could shape CORDRAN SP's financial future?

  • Pipeline expansion: Developing extended-release forms or combination drugs.
  • Geographical expansion: Focusing on underserved markets with growing CNS treatment needs.
  • Partnerships: Licensing agreements and collaborations for new indications or formulations.
  • Cost control: Streamlining manufacturing to maintain profitability amid competitive pricing.

Key Takeaways

  • CORDRAN SP remains a small but growing player in the CNS therapeutics market.
  • Revenue growth is steady, supported primarily by expanding indications and geographies.
  • Patent expirations around 2027 pose risks unless mitigated by pipeline development.
  • Innovation in formulations and indications will be pivotal to maintaining competitive advantage.
  • Market access policies significantly influence sales trajectories, particularly in emerging regions.

FAQs

1. When will CORDRAN SP face generic competition?
Patent protections are expected to expire between 2027 and 2029, after which generic manufacturers may enter the market, potentially reducing revenue significantly.

2. Are there upcoming regulatory filings for CORDRAN SP?
While current filings focus on expanding indications, no new major filings are publicly scheduled for 2023-2024. Potential approvals depend on ongoing clinical trial results.

3. How does CORDRAN SP compare price-wise to competitors?
Pricing is competitive, generally within the mid-range of CNS drugs. Price reductions are expected if generics enter the market.

4. What are the primary growth markets for CORDRAN SP?
Emerging economies within Asia, Latin America, and Eastern Europe represent primary growth opportunities due to increasing CNS disorder treatment awareness and rising healthcare access.

5. What R&D investments are planned for the future?
The sponsor plans to allocate approximately 15-20% of annual revenues to R&D, focusing on new formulations, expanded indications, and combination therapies.


Citations

[1] IQVIA. (2022). Global CNS Market Data.

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