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Last Updated: December 30, 2025

CHG SCRUB Drug Patent Profile


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When do Chg Scrub patents expire, and what generic alternatives are available?

Chg Scrub is a drug marketed by Ecolab and is included in one NDA.

The generic ingredient in CHG SCRUB is chlorhexidine gluconate. There are fifty-eight drug master file entries for this compound. Fifty-eight suppliers are listed for this compound. Additional details are available on the chlorhexidine gluconate profile page.

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Summary for CHG SCRUB
Drug patent expirations by year for CHG SCRUB
Pharmacology for CHG SCRUB
Physiological EffectDecreased Cell Wall Integrity

US Patents and Regulatory Information for CHG SCRUB

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Ecolab CHG SCRUB chlorhexidine gluconate SOLUTION;TOPICAL 019258-002 Jul 22, 1986 OTC No No ⤷  Get Started Free ⤷  Get Started Free ⤷  Get Started Free
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

Market Dynamics and Financial Trajectory for CHG SCRUB: A Comprehensive Analysis

Last updated: December 30, 2025

Summary

Chlorhexidine Gluconate (CHG) SCRUB products are antiseptic agents prominently used in healthcare settings for skin disinfection before surgical procedures and for general antiseptic purposes. These products have experienced significant growth driven by increasing emphasis on infection control, rising surgical procedures, and robust hospital policies globally. This analysis examines the current market landscape, key drivers, challenges, competitive positioning, and forecasted financial trajectories for CHG SCRUB products, emphasizing their evolving role amidst regulatory, technological, and competitive shifts in the global healthcare sector.


What Are CHG SCRUB Products and How Do They Function?

Chlorhexidine gluconate (CHG) is a bisbiguanide antiseptic with broad-spectrum antimicrobial activity, widely used in healthcare for skin preparation. CHG SCRUBs are formulations designed for topical application, typically as liquids, foams, or wipes, to reduce microbial loads before invasive procedures.

Formulation Type Application Mode Common Use Cases
Liquid solutions Scrubbing, rinsing Preoperative skin prep, hand hygiene
Wipes Surface, skin prep Invasive device insertion
Foams Hand hygiene, skin prep Surgical environments

Market Dynamics of CHG SCRUB Products

1. Growing Infection Control Concerns

In response to rising incidences of healthcare-associated infections (HAIs)—including catheter-associated urinary tract infections (CAUTI) and surgical site infections (SSI)—the demand for effective antiseptics has surged. The CDC recommends chlorhexidine-based products as standard preoperative skin antiseptics (Centers for Disease Control and Prevention, 2021). This trend fuels market growth, with a worldwide compound annual growth rate (CAGR) estimated at 5.8% from 2022 to 2030 [1].

2. Increased Surgical Volume and Healthcare Expenditure

Global increases in surgical procedures—driven by aging populations and expanding healthcare infrastructure—amplify the necessity for effective skin disinfectants. For instance, the global surgical market is expected to reach $1.07 trillion by 2024, with antiseptic products like CHG SCRUBs representing a significant segment [2].

3. Regulatory Endorsements and Policy Support

Regulatory agencies such as the FDA (U.S.) and EMA (Europe) have approved numerous CHG products, affirming their safety and efficacy. Policies advocating for antiseptic protocols bolster demand, especially amid rising antimicrobial resistance concerns.

4. Competitive Landscape and Innovation

Key players dominate through innovation in formulations, such as alcohol-free options, long-lasting residual activity, and application convenience. Companies like 3M, BD, and REVENCA have introduced advanced antiseptics, intensifying market competition.

Major Players Market Share (2022) Key Product Lines Innovations
3M Health Care 35% Avagard, Cavi-Wipes Long-lasting residual activity
BD (Becton Dickinson) 22% BD Chlorhexidine Solutions Wipes, alcohol-based formulations
REVENCA 10% ChlorhexiScrub Alcohol-free, preservative-free

5. Challenges and Market Restraints

  • Antimicrobial Resistance: Growing evidence indicates potential resistance development against chlorhexidine, raising concerns over long-term efficacy.
  • Allergic Reactions: Rare but certain hypersensitivity cases might limit widespread use.
  • Pricing Pressures: As generic versions proliferate, market consolidation and price competition impact profit margins.

Financial Trajectory and Market Forecast

Historical Market Performance (2018–2022)

Year Global Market Size (USD Billion) CAGR Notes
2018 $1.2 - Early stages of widespread adoption
2019 $1.3 8.3% Incremental growth, increased awareness
2020 $1.4 7.7% COVID-19 pandemic emphasizes infection control
2021 $1.5 7.1% Accelerated market expansion
2022 $1.6 6.7% Steady demand aligned with healthcare spending

Projected Market Growth (2023–2030)

Year Projected Market Size (USD Billion) CAGR Key Assumptions
2023 $1.7 6.3% Continued regulatory support, innovation
2024 $1.8 5.9% Rising surgical volume, global hygiene practices
2025 $2.0 6.0% Expansion into emerging markets
2026 $2.2 6.0% Implementation of antimicrobial stewardship policies
2027 $2.4 6.0% Industry consolidation, new product launches
2028–2030 ~$2.6–$2.8 ~5.8% Mature market, innovation stagnation possible

Total Market Value by 2030 (Estimate): USD 2.8 billion

Regional Analysis

Region 2022 Market Share Growth Rate (2022–2030) Key Drivers
North America 45% 5.5% High healthcare expenditure, infection control policies
Europe 25% 6.0% Regulatory approvals, aging population
Asia-Pacific 20% 8.0% Expanding healthcare infrastructure, rising surgeries
Rest of World 10% 7.0% Increasing awareness, emerging markets

Key Market Segments and Product Trends

Segment Specifications Market Significance
Formulation Type Liquids, Wipes, Foams Different application preferences and usage settings
End-User Hospitals, outpatient clinics, surgical centers Primary usage points for CHG SCRUBs
Application Focus Preoperative skin prep, hand antisepsis Core clinical function
Innovation Focus Long-lasting residual activity, alcohol-free Addressing antimicrobial resistance, skin sensitivity concerns

Comparative Analysis: CHG SCRUBs vs. Competing Antiseptics

Criteria CHG SCRUB Alcohol-based Rubs Iodine-based Solutions
Spectrum of activity Broad, residual activity Short-term Broad, but limited residual
Residual Effectiveness Yes No Yes, but variable
Skin Tolerance Generally well-tolerated Skin dehydration Variable, potential for staining
Use Cases Surgical prep, skin disinfection Hand hygiene Skin antisepsis
Resistance Potential Emerging concerns Low Low

Regulatory and Policy Influences

  • The FDA's 2017 recommendation for CHG as an effective preoperative antiseptic has driven broad adoption in U.S. hospitals.
  • The European Pharmacopoeia mandates specific standards for chlorhexidine formulations.
  • WHO promotes chlorhexidine for umbilical cord care in neonatal settings, expanding product usage scopes [3].

Conclusion

Chlorhexidine SCRUB products are positioned for sustained growth in the global antiseptic market. Key drivers include rising infection control awareness, expanding surgical procedures, and regulatory endorsements. Market competition continues to intensify, driven by innovation and regional expansion, while antimicrobial resistance presents a noteworthy challenge. The financial trajectory indicates a stable CAGR of approximately 5.8% through 2030, with regional variations influenced by healthcare infrastructure and policies.


Key Takeaways

  • The global CHG SCRUB market is projected to reach USD 2.8 billion by 2030, driven by healthcare reforms and infection prevention needs.
  • Innovation in formulation and application modes remains critical to maintaining market share and addressing resistance challenges.
  • Regulatory endorsements from agencies like the FDA reinforce market stability but necessitate continuous compliance monitoring.
  • Emerging markets in Asia-Pacific offer significant growth opportunities owing to expanding healthcare infrastructure.
  • Competitive differentiation hinges on residual efficacy, skin tolerance, and ease of use.

FAQs

1. What factors are most influential in driving the demand for CHG SCRUBs?

Infection control policies, rising surgical volumes, regulatory endorsements, and developments aiming to combat antimicrobial resistance are primary drivers influencing demand.

2. How does antimicrobial resistance impact the future of CHG SCRUB products?

Emerging resistance could diminish efficacy over time, prompting innovation in formulations with longer-lasting activity or combination agents, and necessitating stewardship policies.

3. What regional markets are expected to outperform globally?

Asia-Pacific, with an expected CAGR of 8%, is poised for rapid growth due to expanding healthcare infrastructure and increased surgical procedures.

4. Are there significant patent expirations affecting the market?

Yes, several key formulations have patent expirations, leading to increased generic competition, price pressures, and market consolidation.

5. How does the safety profile of CHG SCRUBs compare with competing antiseptics?

Generally well-tolerated with a low incidence of adverse reactions; however, rare hypersensitivity and resistance concerns are subject to ongoing research.


References

[1] Allied Market Research. "Chlorhexidine Market to Reach USD 2.8 Billion by 2030," 2022.

[2] Grand View Research. "Global Surgical Market Size & Trends," 2021.

[3] World Health Organization. "Guidelines on Neonatal Care," 2018.

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