Last updated: April 22, 2026
Who Supplies DETROL LA (tolterodine) Pharmaceuticals?
DETROL LA is a branded, extended-release formulation of tolterodine (a muscarinic antagonist) marketed in the US as DETROL LA (tolterodine tartrate) extended release capsules. The brand is owned and marketed by Pfizer Inc. in the United States, and manufacturing and supply for branded products is typically executed through a combination of Pfizer manufacturing sites and contracted partners under Pfizer’s commercial supply chain.
What companies supply DETROL LA in the US supply chain?
Brand owner / marketer
- Pfizer Inc. (US label and brand responsibility for DETROL LA)
Manufacturer and label supply
- DETROL LA is commercially supplied under Pfizer’s branded product labeling. The “supplier” in regulatory terms is the NDA holder/labeler (Pfizer) and the listed manufacturers on the product’s US regulatory label and submissions. The drug label indicates the product is produced for Pfizer’s distribution network.
Regulatory labeling identifies the “labeler” as Pfizer
For US prescription drugs, the “labeler” is the entity responsible for the listed product. For DETROL LA, this is Pfizer.
Which manufacturing sites supply the product dosage form?
DETROL LA is an extended-release capsule dosage form containing tolterodine tartrate. Extended-release supply typically involves:
- capsule fill and tablet/particle manufacturing within Pfizer’s network or qualified contract manufacturers
- controlled release formulation steps and encapsulation under validated processes
- batch release under Pfizer quality systems
The exact site-level manufacturers for DETROL LA depend on the specific market authorization period and the revision cycle of the US labeling and regulatory submissions.
Dosage form supply constraints (extended-release capsules)
- Dosage form: extended-release capsules
- API: tolterodine tartrate
- Supply chain requirement: extended-release particle/formulation and encapsulation under validated dissolution and release-spec controls
What is the API (tolterodine) sourcing landscape?
Tolterodine is a mature small-molecule API with established chemical suppliers. For branded extended-release products, Pfizer’s purchasing typically sources:
- tolterodine tartrate API from qualified suppliers
- excipients and capsule components from qualified vendors
- contract manufacturing steps only when Pfizer approves the technical and quality packages for those stages
Typical vendor categories for branded DETROL LA supply
- API supplier (qualified tolterodine tartrate manufacturer)
- Excipients (extended-release formulation excipients and capsule components)
- Encapsulation and release-formulation partner (only if outsourced; otherwise Pfizer sites)
Who controls supply under the product’s regulatory responsibility?
In US branded prescription drug practice:
- Pfizer controls regulatory responsibility as labeler/brand owner
- site manufacturers execute manufacturing under Pfizer’s quality and release regime
- contractors may manufacture intermediates, finished dosage units, or packaging, subject to qualification and ongoing oversight
Key Takeaways
- Pfizer Inc. is the US brand owner/labeler for DETROL LA.
- DETROL LA’s supply chain includes Pfizer-controlled manufacturing and, when applicable, qualified contract manufacturers for extended-release capsule production.
- API sourcing for tolterodine tartrate is handled via qualified suppliers under Pfizer’s quality system.
FAQs
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Is Pfizer the supplier of DETROL LA?
Pfizer is the brand owner/labeler responsible for the marketed product in the US.
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Who manufactures the extended-release capsule?
Manufacturing is executed by Pfizer manufacturing sites and may involve qualified contract manufacturers for specific steps, under Pfizer quality and release control.
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What is DETROL LA’s active ingredient?
Tolterodine tartrate.
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Is DETROL LA the same as immediate-release tolterodine?
No. DETROL LA is an extended-release formulation designed for controlled drug release.
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How are API and excipient suppliers selected for DETROL LA?
Through Pfizer’s qualified supplier programs tied to quality and validated manufacturing requirements.
References (APA)
[1] Pfizer Inc. (n.d.). DETROL LA (tolterodine tartrate) extended-release capsules: US prescribing information / product labeling. Pfizer.
