Last updated: April 26, 2026
What is AVAGE?
AVAGE is a brand of tretinoin topical cream used for dermatologic indications. The product name “AVAGE” is associated with tretinoin 0.1% (commonly marketed as a once-daily topical for photoaging and acne in the US market).
Who supplies AVAGE?
AVAGE is supplied in the US market by Allergan (brand owner and marketer for the AVAGE label historically associated with Allergan).
Key suppliers (market authorization/labeler level)
| Item |
Supplier/Labeler |
Role in supply chain |
| AVAGE (tretinoin topical) |
Allergan |
Brand holder/marketer tied to the approved US product labeling |
What manufacturers actually produce AVAGE?
Drug product manufacturing for branded topical products is typically performed by one or more contracted manufacturers, while the labeler/holder manages regulatory ownership and supply oversight. For AVAGE, the specific manufacturing sites and contract manufacturers vary by market and label revision cycle.
Which regulatory sources tie AVAGE to its supplier?
- The US FDA NDC Directory lists the product under a specific labeler (the “holder” responsible for the labeled product as submitted to FDA). The labeler for AVAGE is Allergan. [1]
How to verify supplier identity quickly (NDC Directory workflow)
- Search the FDA NDC Directory for “AVAGE”.
- Confirm the labeler field on the listing(s).
- Use the NDC entries to map strength and package form to the same labeler. [1]
What suppliers could show up besides the labeler?
For R&D and procurement diligence, the practical supplier set usually splits into:
- Marketing/labeler entity (FDA labeler in the NDC Directory).
- Contract manufacturer(s) for drug product (finished topical).
- Raw material suppliers for tretinoin and formulation excipients (managed through the contract manufacturing chain).
Key procurement takeaways
- The only fixed “supplier” definition at regulatory level for AVAGE is the FDA NDC labeler, which is Allergan for AVAGE listings. [1]
- Any downstream contract manufacturers are not reliably inferable without tying specific NDC-to-label version details from the package insert and its manufacturing section.
Key Takeaways
- Allergan is the FDA labeler/brand marketer for AVAGE (tretinoin topical) in the US product listings. [1]
- For contract manufacturing and raw-material sourcing, supplier identification requires matching the exact NDC and label revision to the product’s manufacturing disclosures; the regulatory labeler is the stable anchor point. [1]
FAQs
1) Is AVAGE manufactured by Allergan or only marketed by it?
FDA’s NDC Directory identifies Allergan as the labeler for AVAGE listings. The NDC labeler does not, by itself, prove who physically manufactures the finished dosage. [1]
2) What active ingredient is in AVAGE?
AVAGE is a tretinoin topical product associated with 0.1% tretinoin formulations in the brand’s US use context. [1]
3) Where can I confirm the supplier/labeler for AVAGE?
Use the FDA NDC Directory search for AVAGE and read the labeler field from the listing(s). [1]
4) Do all AVAGE strengths share the same supplier?
At the regulatory level, multiple NDC listings can exist by strength and packaging. They can share the same labeler, but each NDC entry should be checked for consistency. [1]
5) What defines “supplier” in a regulatory procurement context for AVAGE?
The most defensible definition for immediate due diligence is the FDA NDC Directory labeler, because it ties directly to the submitted drug product identity in FDA systems. [1]
References
- U.S. Food and Drug Administration (FDA). NDC Directory. (Accessed 2026-04-26). https://www.accessdata.fda.gov/scripts/cder/daf/ (FDA NDC Directory search results for AVAGE).
