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Generated: February 25, 2018

DrugPatentWatch Database Preview

Details for Patent: 9,125,889

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Summary for Patent: 9,125,889
Title:Use of inhibitors of Bruton's tyrosine kinase (Btk)
Abstract: Disclosed herein are methods for treating a cancer comprising: a. administering a Btk inhibitor to a subject sufficient to result in an increase or appearance in the blood of a subpopulation of lymphocytes defined by immunophenotyping; b. determining the expression profile of one or more biomarkers from one or more subpopulation of lymphocytes; and c. administering a second agent based on the determined expression profile.
Inventor(s): Buggy; Joseph J. (Mountain View, CA), Elias; Laurence (Berkeley, CA), Fyfe; Gwen (San Francisco, CA), Hedrick; Eric (Summit, NJ), Loury; David J. (Incline Village, NV), Mody; Tarak D. (Sunnyvale, CA)
Assignee: Pharmacyclics, Inc. (Sunnyvale, CA)
Application Number:14/448,963
Patent Claim Types:
see list of patent claims
Use;

Drugs Protected by US Patent 9,125,889

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Pharmacyclics Inc IMBRUVICA ibrutinib CAPSULE;ORAL 205552-002 Dec 20, 2017 RX Yes No ➤ Sign Up ➤ Sign Up TREATMENT OF WALDENSTROM'S MACROGLOBULINEMIA ➤ Sign Up
Pharmacyclics Inc IMBRUVICA ibrutinib CAPSULE;ORAL 205552-001 Nov 13, 2013 RX Yes Yes ➤ Sign Up ➤ Sign Up FOR THE TREATMENT OF PATIENTS WITH WALDENSTROM'S MACROGLOBULINEMIA ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Non-Orange Book US Patents Family Members for Patent 9,125,889

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
8,754,090 Use of inhibitors of bruton's tyrosine kinase (Btk) ➤ Sign Up
9,801,883 Use of inhibitors of bruton's tyrosine kinase (Btk) ➤ Sign Up
9,814,721 Use of inhibitors of bruton'S tyrosine kinase (BTK) ➤ Sign Up
8,999,999 Use of inhibitors of Bruton's tyrosine kinase (Btk) ➤ Sign Up
9,801,881 Use of inhibitors of bruton's tyrosine kinase (BTK) ➤ Sign Up
Patent No. Title Estimated Patent Expiration

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International Patents Family Members for US Patent 9,125,889

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Ukraine 107707 ➤ Sign Up
Singapore 186077 ➤ Sign Up
New Zealand 717373 ➤ Sign Up
New Zealand 702485 ➤ Sign Up
New Zealand 604040 ➤ Sign Up
Mexico 342405 ➤ Sign Up
Mexico 2012014049 ➤ Sign Up
South Korea 101580714 ➤ Sign Up
South Korea 20130086957 ➤ Sign Up
Japan 2017039767 ➤ Sign Up
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Fuji
Healthtrust
Chinese Patent Office
Julphar
Chubb
Medtronic
Merck
Cerilliant
Cantor Fitzgerald

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