Details for Patent: 8,980,901
Summary for Patent: 8,980,901
| Title: | 5-fluoro-3-phenyl-2[1-(9H-purin-6-ylamino)propyl]-3H-quinazolin-4-one and 6-fluoro-3-phenyl-2-[1-(9H-purin-6-ylamino)ethyl]-3H-quinazolin-4-one as inhibitors of human phosphatidylinositol 3-kinase delta |
| Abstract: | Compounds that inhibit PI3Kδ activity, including compounds that selectively inhibit PI3Kδ activity, are disclosed. Methods of inhibiting phosphatidylinositol 3-kinase delta isoform (PI3Kδ) activity, and methods of treating diseases, such as disorders of immunity and inflammation in which PI3Kδ plays a role in leukocyte function, using the compounds also are disclosed. Exemplary compounds disclosed in this application are shown below: |
| Inventor(s): | Kerry W. Fowler, Danwen Huang, Edward A. Kesicki, Hua Chee Ooi, Amy Oliver, Fuqiang Ruan, Jennifer Treiberg, Kamal Deep PURI |
| Assignee: | Gilead Sciences Inc |
| Application Number: | US14/049,163 |
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Patent Claim Types: see list of patent claims | Use; Composition; |
Drugs Protected by US Patent 8,980,901
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
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International Family Members for US Patent 8,980,901
| Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
|---|---|---|---|---|---|
| European Patent Office | 1761540 | ⤷ Start Trial | PA2017004 | Lithuania | ⤷ Start Trial |
| European Patent Office | 1761540 | ⤷ Start Trial | 300867 | Netherlands | ⤷ Start Trial |
| European Patent Office | 1761540 | ⤷ Start Trial | 122017000008 | Germany | ⤷ Start Trial |
| European Patent Office | 1761540 | ⤷ Start Trial | CA 2017 00007 | Denmark | ⤷ Start Trial |
| >Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |
