Details for Patent: 8,754,091
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Which drugs does patent 8,754,091 protect, and when does it expire?
Patent 8,754,091 protects IMBRUVICA and is included in three NDAs.
Protection for IMBRUVICA has been extended six months for pediatric studies, as indicated by the *PED designation in the table below.
This patent has one hundred and sixty-one patent family members in twenty-six countries.
Summary for Patent: 8,754,091
Title: | Inhibitors of bruton's tyrosine kinase |
Abstract: | Disclosed herein are compounds, including compounds having the structure of Formula (A), (B), (C), and (D), as described in further detail herein, that form covalent bonds with Bruton's tyrosine kinase (Btk). Also described are irreversible inhibitors of Btk. Methods for the preparation of the compounds are disclosed. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the Btk inhibitors are disclosed, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions. |
Inventor(s): | Honigberg; Lee (San Francisco, CA), Verner; Erik (Belmont, CA), Pan; Zhengying (Austin, TX) |
Assignee: | Pharmacyclics, Inc. (Sunnyvale, CA) |
Application Number: | 13/542,440 |
Patent Litigation and PTAB cases: | See patent lawsuits and PTAB cases for patent 8,754,091 |
Patent Claim Types: see list of patent claims | Composition; Formulation; Compound; Dosage form; |
Drugs Protected by US Patent 8,754,091
International Family Members for US Patent 8,754,091
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
---|---|---|---|---|---|
Austria | E531263 | ⤷ Try a Trial | |||
Australia | 2006348662 | ⤷ Try a Trial | |||
Australia | 2008232762 | ⤷ Try a Trial | |||
Australia | 2010201052 | ⤷ Try a Trial | |||
Australia | 2012205166 | ⤷ Try a Trial | |||
Brazil | PI0622054 | ⤷ Try a Trial | |||
Brazil | PI0622277 | ⤷ Try a Trial | |||
>Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |