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Last Updated: July 25, 2021

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Details for Patent: 8,741,866


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Which drugs does patent 8,741,866 protect, and when does it expire?

Patent 8,741,866 protects ONPATTRO and is included in one NDA.

This patent has seventy-six patent family members in twenty-eight countries.

Summary for Patent: 8,741,866
Title:Compositions and methods for inhibiting expression of transthyretin
Abstract: The invention relates to a double-stranded ribonucleic acid (dsRNA) targeting a transthyretin (TTR) gene, and methods of using the dsRNA to inhibit expression of TTR.
Inventor(s): Sah; Dinah Wen-Yee (Boston, MA), Hinkle; Gregory (Plymouth, MA), Alvarez; Rene (Boxborough, MA), Milstein; Stuart (Cambridge, MA), Chen; Qingmin (Lincoln, MA)
Assignee: Alnylam Pharmaceuticals, Inc. (Cambridge, MA)
Application Number:13/410,262
Patent Claim Types:
see list of patent claims
Use; Formulation;

Drugs Protected by US Patent 8,741,866

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Alnylam Pharms Inc ONPATTRO patisiran sodium SOLUTION;INTRAVENOUS 210922-001 Aug 10, 2018 RX Yes Yes ⤷  Try it Free ⤷  Try it Free TREATMENT OF POLYNEUROPATHY OF HEREDITARY TRANSTHYRETIN-MEDIATED AMYLOIDOSIS ⤷  Try it Free
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 8,741,866

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 2009307677 ⤷  Try it Free
Australia 2015249072 ⤷  Try it Free
Australia 2017225110 ⤷  Try it Free
Australia 2019216630 ⤷  Try it Free
Brazil PI0919732 ⤷  Try it Free
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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Serving leading biopharmaceutical companies globally:

McKinsey
AstraZeneca
Express Scripts
Merck
Medtronic
Johnson and Johnson

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