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Details for Patent: 8,546,399

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Patent 8,546,399 protects VENCLEXTA and is included in one NDA.

This patent has seventy-six patent family members in thirty-five countries.

Summary for Patent: 8,546,399

Title:Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases
Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
Inventor(s): Bruncko; Milan (Green Oaks, IL), Ding; Hong (Gurnee, IL), Doherty; George A. (Libertyville, IL), Elmore; Steven W. (Northbrook, IL), Hasvold; Lisa A. (Grayslake, IL), Hexamer; Laura (Grayslake, IL), Kunzer; Aaron R. (Schaumburg, IL), Song; Xiaohong (Grayslake, IL), Souers; Andrew J. (Evanston, IL), Sullivan; Gerard M. (Lake Villa, IL), Tao; Zhi-Fu (Gurnee, IL), Wang; Gary T. (Libertyville, IL), Wang; Le (Vernon Hills, IL), Wang; Xilu (Grayslake, IL), Wendt; Michael D. (Vernon Hills, IL), Mantei; Robert (Franklin, WI), Hansen; Todd M. (Grayslake, IL)
Assignee: Abbvie Inc. (North Chicago, IL)
Application Number:12/787,682
Patent Claim Types:
see list of patent claims
Compound; Composition;
Patent Metrics:
Source: PatentQuant.com
Field: Pharmaceuticals
Back Citations: 0th percentile
Forward Citations: 15th percentile

Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use
Abbvie Inc
VENCLEXTA
venetoclax
TABLET;ORAL208573-001Apr 11, 2016RXNo8,546,399► subscribeYY
Abbvie Inc
VENCLEXTA
venetoclax
TABLET;ORAL208573-002Apr 11, 2016RXNo8,546,399► subscribeYY
Abbvie Inc
VENCLEXTA
venetoclax
TABLET;ORAL208573-003Apr 11, 2016RXYes8,546,399► subscribeYY
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Non-Orange Book Patents for Patent: 8,546,399

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
9,174,982Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases► subscribe
8,580,794Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases► subscribe
9,034,875Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases► subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Because of the complexity of determining patent expiration dates it is advisable to have patent counsel verify freedom to operate.

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International Patent Family for Patent: 8,546,399

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina076705► subscribe
Argentina079124► subscribe
Australia2010254160► subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

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