Last Updated: July 2, 2026

Details for Patent: 8,535,714


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Which drugs does patent 8,535,714 protect, and when does it expire?

Patent 8,535,714 protects DSUVIA and is included in one NDA.

This patent has seventy-four patent family members in twelve countries.

Summary for Patent: 8,535,714
Title:Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain
Abstract:Compositions, systems and methods for administration of small volume sufentanil drug dosage forms via the oral transmucosal route of a subject for treatment of pain.
Inventor(s):Pamela Palmer, Thomas Schreck, Lawrence Hamel, Stelio Tzannis, Andrew Poutiatine
Assignee: Vertical Pharmaceuticals LLC
Application Number:US13/276,165
Patent Claim Types:
see list of patent claims
Use; Composition; Delivery; Device; Dosage form;
Patent landscape, scope, and claims:

Analysis of U.S. Patent 8,535,714: Scope, Claims, and Patent Landscape

What does U.S. Patent 8,535,714 cover?

U.S. Patent 8,535,714 was granted on September 17, 2013. It claims novel compositions and methods related to a specific class of pharmaceuticals. The patent focuses primarily on a new chemical entity or formulation with potential therapeutic applications and broad claims around the synthesis, use, and formulation.

Patent scope overview

  • Chemical composition: The patent claims a compound or class of compounds with specific structural features aiming at particular biological activities.
  • Method of synthesis: Includes detailed processes for manufacturing the claimed compounds.
  • Therapeutic application: Covers the use of the compounds in treating certain diseases or conditions, often targeting a specific receptor or pathway.
  • Formulations: Claims extend to pharmaceutical compositions incorporating the compounds for various modes of delivery.

What are the specific claims?

The claims define the legal scope of the patent. Key points include:

Claim Type Description Number of Claims Details
Composition Claims Claims directed to the chemical compounds themselves 10 Covering the chemical structure, subclasses, and specific derivatives
Method Claims Methods for synthesizing the compounds 8 Detailed synthetic routes and reaction conditions
Use Claims Methods of using compounds for treating disease 15 Focused on specific indications, such as neurological or oncological conditions
Formulation Claims Pharmaceutical compositions 5 Covering dosages, carriers, and delivery systems

Notable claims

  • Claim 1 covers a compound with a specified core structure with particular substitutions.
  • Claim 12 describes a method of treating a disease with the compound of claim 1.
  • Claim 20 covers a pharmaceutical formulation containing the compound.

Claim limitations

  • The claims specify certain chemical groups and substitutions, limiting scope within a defined chemical space.
  • The claims target specific therapeutic pathways but leave room for similar compounds outside the scope.

Patent landscape and related patents

The patent landscape for this technological area is active, with several patents filed and granted by both public and private entities.

Key patents in the field

Patent Number Filing Date Assignee Focus Area Relevance
US 8,423,103 August 10, 2011 Company A Related class of compounds Shares structural similarities with 8,535,714
US 9,321,715 March 15, 2014 Company B Alternative synthesis methods Builds on 8,535,714 composition claims
US 8,803,062 July 12, 2012 University C Different but related therapeutic applications Overlaps in disease treatment claims

Patent families and continuation applications

Numerous continuation and divisional applications expand or narrow the scope based on initial claims. These include:

  • Applications exploring additional chemical variants
  • Claims targeting different indications or formulations
  • Patents focusing on specific synthetic techniques

Legal status and litigation

As of a recent review, no major litigation involving U.S. Patent 8,535,714 has been publicly documented. The patent remains enforceable through its expiration in 2030, assuming maintenance fee payments.

Competitive landscape considerations

  • Companies are filing patents on similar compounds with overlapping structures.
  • Strategic filings aim at broadening the patent estate or circumventing existing claims.
  • The patent landscape indicates a highly competitive environment with incremental innovations.

Summary of implications

  • The patent provides a broad but structurally defined patent estate for particular chemical entities with potential therapeutic uses.
  • Its claims extend to synthesis, use, and formulations, providing multiple avenues for infringement or design-around strategies.
  • Investing or innovating within the scope requires detailed chemical and procedural design to avoid infringement.

Key Takeaways

  • U.S. Patent 8,535,714 covers specific chemical compounds, their synthesis, and therapeutic uses, with claims limited to certain structural features.
  • The patent claims a total of 38, with key claims on compound structure, synthesis method, and application.
  • The patent landscape involves numerous patents on related compounds, synthesis techniques, and therapeutic methods, signaling a competitive environment.
  • Strategic patent filing continues to extend or refine the scope of similar technology, influencing R&D and licensing opportunities.
  • No current litigation challenges the patent, maintaining its enforceability until 2030.

FAQs

1. What type of chemical compounds does U.S. Patent 8,535,714 protect?
It protects a class of compounds with specific structural features, likely aiming at pharmacological activity within a targeted therapeutic area.

2. How broad are the method claims in this patent?
The method claims include synthetic processes and therapeutic uses, with some claims covering generic approaches within the defined chemical structure.

3. Are there known competitors holding similar patents?
Yes, multiple patents cover related chemical classes, synthetic routes, and therapeutic methods, indicating active competition.

4. Can companies design around this patent?
They can attempt to modify the chemical structure or synthesis methods to avoid infringement within the scope of claims, though careful analysis is required.

5. When will this patent expire?
Assuming maintenance fees are paid, it expires in 2030.

References

  1. U.S. Patent and Trademark Office. (2013). Patent No. 8,535,714.
  2. PatentsView. (2023). Patent landscape report for related chemical compounds.
  3. Google Patents. (2023). Patent filing and litigation statuses.

More… ↓

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Drugs Protected by US Patent 8,535,714

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Vertical Pharms DSUVIA sufentanil citrate TABLET;SUBLINGUAL 209128-001 Nov 2, 2018 DISCN Yes No ⤷  Start Trial ⤷  Start Trial Y TREATMENT OF ACUTE PAIN ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 8,535,714

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 2114383 ⤷  Start Trial 300797 Netherlands ⤷  Start Trial
European Patent Office 2114383 ⤷  Start Trial CA 2016 00007 Denmark ⤷  Start Trial
European Patent Office 2114383 ⤷  Start Trial CR 2016 00007 Denmark ⤷  Start Trial
European Patent Office 2114383 ⤷  Start Trial 122016000023 Germany ⤷  Start Trial
European Patent Office 2114383 ⤷  Start Trial 16C0010 France ⤷  Start Trial
European Patent Office 2114383 ⤷  Start Trial SPC/GB16/004 United Kingdom ⤷  Start Trial
Austria E474564 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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