Last Updated: October 1, 2026

Details for Patent: 8,440,854

Name: Drug Patent Intelligence for US Patent 8440854
Creator: DrugPatentWatch
License: https://www.drugpatentwatch.com/terms.php

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Which drugs does patent 8,440,854 protect, and when does it expire?

Patent 8,440,854 protects SKYCLARYS and is included in one NDA.

This patent has thirty-two patent family members in twenty-six countries.

Summary for Patent: 8,440,854

Title:	Antioxidant inflammation modulators: oleanolic acid derivatives with amino acid and other modifications at C-17
Abstract:	This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.
Inventor(s):	Eric Anderson, Xin Jiang, Melean Visnick
Assignee:	Reata Pharmaceuticals Holdings LLC
Application Number:	US13/356,455
Patent Claim Types: see list of patent claims	Composition; Delivery;

Drugs Protected by US Patent 8,440,854

Glossary

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
Biogen Us	SKYCLARYS	omaveloxolone	CAPSULE;ORAL	216718-001	Feb 28, 2023		RX	Yes	Yes	8,440,854	⤷ Start Trial	Y				⤷ Start Trial
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

International Family Members for US Patent 8,440,854

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Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Australia	2009237579	⤷ Start Trial
Brazil	PI0911457	⤷ Start Trial
Canada	2721838	⤷ Start Trial
China	102083442	⤷ Start Trial
China	104177468	⤷ Start Trial
Colombia	6311071	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration	>Supplementary Protection Certificate	>SPC Country	>SPC Expiration

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