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Last Updated: March 19, 2024

Details for Patent: 8,426,389


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Which drugs does patent 8,426,389 protect, and when does it expire?

Patent 8,426,389 protects SIVEXTRO and is included in two NDAs.

This patent has forty-one patent family members in twenty-eight countries.

Summary for Patent: 8,426,389
Title:Crystalline form of R)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxy- methyl oxazolidin-2-one dihydrogen phosphate
Abstract: A crystalline form of crystalline (R)-3-(4-(2-(2-methyltetrazol-5-yl)-pyridin-5-yl)-3-fluorophenyl)-5-hydro- xymethyl oxazolidin-2-one dihydrogen phosphate, methods of making the crystalline form and pharmaceutical compositions comprising the crystalline form are useful antibiotics. Further, the derivatives of the present invention may exert potent antibacterial activity versus various human and animal pathogens, including Gram-positive bacteria such as Staphylococi, Enterococci and Streptococi , anaerobic microorganisms such as Bacteroides and Clostridia, and acid-resistant microorganisms such as Mycobacterium tuberculosis and Mycobacterium avium. Accordingly, the compositions comprising the crystalline form may be used in antibiotics.
Inventor(s): Reichenbacher; Katharina (Riehen, CH), Duguid; Robert J. (Glenmont, NY), Ware; Jacqueline A. (Troy, NY), Phillipson; Douglas (Del Mar, CA)
Assignee: Trius Therapeutics, Inc. (San Diego, CA)
Application Number:12/699,864
Patent Claim Types:
see list of patent claims
Compound; Composition; Use; Process;

Drugs Protected by US Patent 8,426,389

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Cubist Pharms Llc SIVEXTRO tedizolid phosphate POWDER;INTRAVENOUS 205436-001 Jun 20, 2014 RX Yes Yes ⤷  Try a Trial ⤷  Try a Trial Y Y METHOD OF TREATING BACTERIAL INFECTIONS ⤷  Try a Trial
Cubist Pharms Llc SIVEXTRO tedizolid phosphate TABLET;ORAL 205435-001 Jun 20, 2014 RX Yes Yes ⤷  Try a Trial ⤷  Try a Trial Y Y METHOD OF TREATING BACTERIAL INFECTIONS ⤷  Try a Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 8,426,389

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
African Regional IP Organization (ARIPO) 2987 ⤷  Try a Trial
Australia 2010210627 ⤷  Try a Trial
Brazil PI1008829 ⤷  Try a Trial
Canada 2751392 ⤷  Try a Trial
Chile 2011001855 ⤷  Try a Trial
China 102439006 ⤷  Try a Trial
China 107082790 ⤷  Try a Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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