DrugPatentWatch Database Preview
Details for Patent: 8,377,921
Which drugs does patent 8,377,921 protect, and when does it expire?
Patent 8,377,921 protects ZYKADIA and is included in two NDAs.
This patent has one hundred patent family members in forty-six countries.
Summary for Patent: 8,377,921
| Title: | Compounds and compositions as protein kinase inhibitors |
| Abstract: | The invention provides novel pyrimidine and pyridine derivatives and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine and pyridine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of anaplastic lymphoma kinase (ALK) activity, focal adhesion kinase (FAK), zeta-chain-associated protein kinase 70 (ZAP-70), insulin-like growth factor (IGF-1R), or a combination thereof. |
| Inventor(s): | Michellys; Pierre-Yves (San Marcos, CA), Pei; Wei (San Diego, CA), Marsilje; Thomas H. (San Diego, CA), Chen; Bei (San Diego, CA), Uno; Tetsuo (San Diego, CA) |
| Assignee: | IRM LLC (Hamilton, BM) |
| Application Number: | 13/172,572 |
|
Patent Claim Types: see list of patent claims | Use; |
Drugs Protected by US Patent 8,377,921
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Novartis Pharms Corp | ZYKADIA | ceritinib | CAPSULE;ORAL | 205755-001 | Apr 29, 2014 | DISCN | Yes | No | Start Trial | Start Trial | TREATMENT OF A CANCER MEDIATED BY AN ANAPLASTIC LYMPHOMA KINASE (ALK) | Start Trial | ||||
| Novartis Pharms Corp | ZYKADIA | ceritinib | TABLET;ORAL | 211225-001 | Mar 18, 2019 | RX | Yes | Yes | Start Trial | Start Trial | TREATMENT OF A CANCER MEDIATED BY AN ANAPLASTIC LYMPHOMA KINASE (ALK) | Start Trial | ||||
| >Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
International Family Members for US Patent 8,377,921
| Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
|---|---|---|---|---|---|
| Argentina | 064197 | Start Trial | |||
| Argentina | 077849 | Start Trial | |||
| Argentina | 107966 | Start Trial | |||
| Australia | 2007333394 | Start Trial | |||
| Australia | 2008296479 | Start Trial | |||
| Australia | 2008296545 | Start Trial | |||
| Australia | 2010210018 | Start Trial | |||
| >Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |
