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Last Updated: December 5, 2019

DrugPatentWatch Database Preview

Details for Patent: 8,334,373

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Which drugs does patent 8,334,373 protect, and when does it expire?

Patent 8,334,373 protects ONPATTRO and is included in one NDA.

This patent has five patent family members in four countries.

Summary for Patent: 8,334,373
Title:Nuclease resistant double-stranded ribonucleic acid
Abstract: This invention relates to modified double-stranded oligoribonucleic acid (dsRNA) having improved stability in cells and biological fluids, and methods of making and identifying dsRNA having improved stability, and of using the dsRNA to inhibit the expression or function of a target gene.
Inventor(s): Vornlocher; Hans-Peter (Cambridge, MA), Roehl; Ingo (Cambridge, MA), Hadwiger; Philipp (Cambridge, MA), Zimmermann; Tracy Stage (Cambridge, MA), Manoharan; Muthiah (Cambridge, MA), Rajeev; Kallanthottathil G. (Cambridge, MA), Akinc; Akin (Cambridge, MA)
Assignee: Alnylam Pharmaceuticals, Inc. (Cambridge, MA)
Application Number:13/038,672
Patent Claim Types:
see list of patent claims
Use; Composition; Compound;

Drugs Protected by US Patent 8,334,373

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Alnylam Pharms Inc ONPATTRO patisiran sodium SOLUTION;INTRAVENOUS 210922-001 Aug 10, 2018 RX Yes Yes   Start Trial   Start Trial Y Y   Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 8,334,373

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 2005247509   Start Trial
Canada 2568013   Start Trial
European Patent Office 1765847   Start Trial
European Patent Office 2399924   Start Trial
World Intellectual Property Organization (WIPO) 2005115481   Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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Serving leading biopharmaceutical companies globally:

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