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Last Updated: September 27, 2020

DrugPatentWatch Database Preview

Details for Patent: 8,299,057

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Which drugs does patent 8,299,057 protect, and when does it expire?

Patent 8,299,057 protects ROZLYTREK and is included in one NDA.

This patent has thirty-two patent family members in twenty-four countries.

Summary for Patent: 8,299,057
Title:Substituted indazole derivatives active as kinase inhibitors
Abstract: Substituted indazole derivatives of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful in therapy in the treatment of diseases associated with a deregulated protein kinase activity, like cancer.
Inventor(s): Lombardi Borgia; Andrea (Paullo, IT), Menichincheri; Maria (Milan, IT), Orsini; Paolo (Legnano, IT), Panzeri; Achille (Merate, IT), Perrone; Ettore (Boffalora Sopra Ticino, IT), Vanotti; Ermes (Milan, IT), Nesi; Marcella (Saronno, IT), Marchionni; Chiara (Milan, IT)
Assignee: Nerviano Medical Sciences S.R.L. (Nerviano (MI), IT)
Application Number:12/668,745
Patent Claim Types:
see list of patent claims
Composition; Compound; Process; Device;

Drugs Protected by US Patent 8,299,057

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Genentech Inc ROZLYTREK entrectinib CAPSULE;ORAL 212725-001 Aug 15, 2019 RX Yes No   Start Trial   Start Trial Y Y   Start Trial
Genentech Inc ROZLYTREK entrectinib CAPSULE;ORAL 212725-002 Aug 15, 2019 RX Yes Yes   Start Trial   Start Trial Y Y   Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 8,299,057

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
07112881Jul 20, 2007
PCT Information
PCT FiledJuly 08, 2008PCT Application Number:PCT/EP2008/058861
PCT Publication Date:January 29, 2009PCT Publication Number: WO2009/013126

International Family Members for US Patent 8,299,057

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina 067599   Start Trial
Australia 2008280283   Start Trial
Brazil PI0814628   Start Trial
Canada 2693901   Start Trial
Chile 2008002129   Start Trial
China 101754956   Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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