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Last Updated: April 26, 2024

Details for Patent: 8,168,775


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Which drugs does patent 8,168,775 protect, and when does it expire?

Patent 8,168,775 protects ONPATTRO and is included in one NDA.

This patent has eighty-nine patent family members in twenty-eight countries.

Summary for Patent: 8,168,775
Title:Compositions and methods for inhibiting expression of transthyretin
Abstract: The invention relates to a double-stranded ribonucleic acid (dsRNA) targeting a transthyretin (TTR) gene, and methods of using the dsRNA to inhibit expression of TTR.
Inventor(s): Sah; Dinah Wen-Yee (Boston, MA), Hinkle; Gregory (Plymouth, MA), Alvarez; Rene (Cambridge, MA), Milstein; Stuart (Cambridge, MA), Chen; Qingmin (Lincoln, MA)
Assignee: Alnylam Pharmaceuticals, Inc. (Cambridge, MA)
Application Number:12/582,669
Patent Claim Types:
see list of patent claims
Use; Composition; Compound;

Drugs Protected by US Patent 8,168,775

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Alnylam Pharms Inc ONPATTRO patisiran sodium SOLUTION;INTRAVENOUS 210922-001 Aug 10, 2018 RX Yes Yes ⤷  Try a Trial ⤷  Try a Trial Y Y TREATMENT OF POLYNEUROPATHY OF HEREDITARY TRANSTHYRETIN-MEDIATED AMYLOIDOSIS ⤷  Try a Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 8,168,775

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 2009307677 ⤷  Try a Trial
Australia 2015249072 ⤷  Try a Trial
Australia 2017225110 ⤷  Try a Trial
Australia 2019216630 ⤷  Try a Trial
Australia 2021203272 ⤷  Try a Trial
Australia 2023248138 ⤷  Try a Trial
Brazil PI0919732 ⤷  Try a Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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