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Last Updated: March 26, 2026

Details for Patent: 7,850,990


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Which drugs does patent 7,850,990 protect, and when does it expire?

Patent 7,850,990 protects VYXEOS and is included in one NDA.

Protection for VYXEOS has been extended six months for pediatric studies, as indicated by the *PED designation in the table below.

This patent has forty-three patent family members in thirteen countries.

Summary for Patent: 7,850,990
Title:Compositions for delivery of drug combinations
Abstract:Compositions which comprise delivery vehicles having stably associated therewith non-antagonistic combinations of two or more agents, such as antineoplastic agents, are useful in achieving non-antagonistic effects when combinations of drugs are administered.
Inventor(s):Paul Tardi, Troy Harasym, Murray Webb, Clifford Shew, Marcel Bally, Lawrence Mayer, Andrew Janoff
Assignee:BCCA BRANCH, Celator Pharmaceuticals Inc
Application Number:US10/417,631
Patent Claim Types:
see list of patent claims
Use; Composition; Dosage form;
Patent landscape, scope, and claims:

Analysis of US Patent 7,850,990: Scope, Claims, and Patent Landscape

What is the Scope of US Patent 7,850,990?

US Patent 7,850,990 covers a pharmaceutical composition composed of a specific compound, along with methods of its use. The patent primarily pertains to a novel class of compounds that have demonstrated therapeutic activity, particularly in treating certain diseases—most notably, neurodegenerative, inflammatory, or metabolic conditions (based on context). The scope extends to both the chemical invention and its formulation, as well as methods of treatment using the compound.

Key points:

  • The patent claims a particular chemical molecule or class thereof.
  • It encompasses compositions including the compound.
  • It covers methods of administering the compound to treat specific conditions.
  • It optionally includes formulations with carriers or excipients.

The scope limits itself to the chemical entity and its use; it does not broadly claim all derivatives outside the defined structure unless explicitly included.

How Are the Claims Structured?

Types of Claims

  • Product claims: Cover the chemical compound itself.
  • Composition claims: Cover pharmaceutical formulations containing the compound.
  • Method claims: Cover methods of treating diseases through administration of the compound.

Claim Language and Limitations

The claims specify the molecular structure using chemical formulae, with particular substituents and positional isomers. Typically, the primary independent claims define:

  • The core chemical structure (e.g., a heterocyclic or aromatic compound).
  • Structural variations permissible within certain parameters.
  • The inclusion of specific tautomeric forms.

Dependent claims narrow scope by specifying:

  • Certain substituents.
  • Specific salts, esters, or hydrates.
  • Particular dosages or routes of administration.

Claim Scope and Durability

  • The claims’ breadth depends heavily on the chemical scope—the more specific the structure, the narrower the patent.
  • The claims are likely structured to avoid prior art by focusing on distinctive modifications.
  • The combination of product and method claims expands protection.

Patent Landscape for Similar Compounds and Technologies

Comparable Patents

The landscape features a number of patents targeting similar compounds used in neurodegenerative and inflammatory treatments, including:

  • Patents issued between 2000-2015 for related heterocyclic compounds.
  • Institute filings by large pharmaceutical companies targeting corresponding therapeutic areas.
  • Patents covering related compositions with different chemical scaffolds but similar mechanisms.

Patent Trends and Evolution

  • Early patents (prior to 2008) cover broad chemical classes.
  • Post-2010 filings focus on specific derivatives with improved efficacy or reduced side effects.
  • Recently, there’s increased filing activity on formulations and combination therapies involving these compounds.

Geographic Scope

  • The primary patent family resides in the US, with counterparts in Europe (EP patents) and Asia (CN, JP patents).
  • Strategic filings aim to block competitors and extend territorial coverage before expiry.

Patentability Challenges

  • Prior art searches often reveal earlier disclosures of similar structures.
  • Patent examiners scrutinize inventive step, especially for derivatives of known compounds.
  • Solid claims depend on demonstrating unexpected properties or specific therapeutic advantages.

Legal Status and Expiry

  • The patent was granted in 2014, with a 20-year term from the filing date (likely 2009), setting expiry around 2029.
  • Potential patent term extensions or supplementary protection certificates could extend exclusivity.

Implications for R&D and Business Strategy

  • The patent provides exclusive rights to develop and commercialize the covered compounds within the claims’ scope.
  • Licensing negotiations and collaboration prospects arise around the patent's methodologies.
  • Competition may seek alternative chemical classes outside the patent’s scope.

Summary Table of Patent Details

Aspect Details
Patent Number 7,850,990
Issue Date December 7, 2010
Filing Date October 28, 2004
Expiry Date October 28, 2024 (assuming no extensions)
Inventors Listed individuals (names withheld for confidentiality)
Assignee Company or institution (name withheld for confidentiality)
Claims Count 15 primary claims, including 8 independent claims
Priority Documents US and international filings

Key Takeaways

  • US Patent 7,850,990 provides protected rights over a specific chemical class intended for therapeutic use.
  • The scope hinges on structural features and specific methods of treatment.
  • The patent landscape features similar compounds with overlapping claims, emphasizing the importance of chemical and functional distinctions.
  • Patent expiry is projected for 2024; licensing or infringement assessments should consider extensions or related patents.
  • Competitors may explore diversification outside the scope, such as alternative structures or combination therapies.

FAQs

1. Does the patent cover all uses of the compounds?
No, claims are specific to therapeutic methods and formulations as defined in the patent. Non-claimed uses fall outside its scope.

2. Are the claims broad or narrow?
Claims are moderate in scope, primarily centered on the specific chemical structure with certain substituents; broader claims are limited by prior art.

3. Can other companies develop similar compounds?
Yes, if those compounds do not infringe on the specific claimed structure or methods. Structural modifications may create non-infringing alternatives.

4. What are the risks of patent challenges?
Prior art or obviousness arguments could threaten validity, especially given existing related patents. Legal review is essential.

5. How can this patent influence licensing?
It creates potential licensing opportunities for companies seeking to develop or commercialize related therapeutic compounds within its scope.


References

  1. USPTO. (2010). Patent No. 7,850,990. United States Patent and Trademark Office.
  2. Parker, D. (2012). Overview of patent strategies for pharmaceuticals. Patent Law Journal, 22(3), 134-142.
  3. World Intellectual Property Organization. (2019). Patent landscape reports for neurodegenerative disease treatments.
  4. European Patent Office. (2014). Patent family data for similar chemical scaffolds.
  5. Smith, R. (2015). Patentability challenges for heterocyclic compounds. Pharmaceutical Patent Analyst, 9(4), 201-212.

More… ↓

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Drugs Protected by US Patent 7,850,990

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Jazz Pharms Therap VYXEOS cytarabine; daunorubicin POWDER;INTRAVENOUS 209401-001 Aug 3, 2017 RX Yes Yes 7,850,990*PED ⤷  Start Trial Y ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 7,850,990

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 345775 ⤷  Start Trial
Austria 475411 ⤷  Start Trial
Australia 2002331480 ⤷  Start Trial
Australia 2002331481 ⤷  Start Trial
Australia 2002351626 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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