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Serving leading biopharmaceutical companies globally:

Harvard Business School
Colorcon
Medtronic
Johnson and Johnson
McKesson
Queensland Health
Farmers Insurance
Moodys
Merck
Federal Trade Commission

Generated: January 21, 2018

DrugPatentWatch Database Preview

Details for Patent: 7,758,890

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Which drugs does patent 7,758,890 protect, and when does it expire?

Patent 7,758,890 protects RYANODEX and is included in one NDA.

This patent has eight patent family members in five countries.
Summary for Patent: 7,758,890
Title:Treatment using dantrolene
Abstract: Low volume safe for injection formulations of dantrolene yield significant advantages over the currently approved and marketed dantrolene for MH threatening anesthetic crisis. Once dantrolene can be made immediately available to patients triggered of MH, the anesthesiologist will be able to focus exclusively on the management of the patient's physiologic status in this complex and evolving crisis, not on the laborious and time consuming reconstitution process of the rescue agent. Additionally, a safe for injection low volume formulation of dantrolene can be made widely available to non-anesthesiologist practitioners who have occasion to use dantrolene intravenously in the treatment of other potentially life threatening conditions, including in the field. The low volume, safe for injection formulations of dantrolene, as well as other formulations of dantrolene, have significant advantages over currently used approaches to the prevention and treatment of pumphead, and other neurological, cognitive and motor dysfunction incident to iatrogenically or trauma induced situations of altered blood flow, including those incurred during surgical procedures involving CPB or related procedures, as well as those incurred during non-normothermic episodes caused iatrogenically or by disease.
Inventor(s): Anderson; David (Ashland, VA), Cameransi, Jr.; Benjamin G. (Georgetown, SC), Conklin; Vincent M. (Richmond, VA)
Assignee: Lyotropic Therapeutics, Inc. (Ashland, VA)
Application Number:10/788,413
Patent Claim Types:
see list of patent claims
Composition; Formulation; Compound;

Drugs Protected by US Patent 7,758,890

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Eagle Pharms RYANODEX dantrolene sodium FOR SUSPENSION;INTRAVENOUS 205579-001 Jul 22, 2014 RX Yes Yes ➤ Subscribe ➤ Subscribe Y ➤ Subscribe
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Non-Orange Book US Patents Family Members for Patent 7,758,890

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
9,603,840 Treatment using dantrolene ➤ Subscribe
8,110,225 Treatment using dantrolene ➤ Subscribe
8,604,072 Treatment using dantrolene ➤ Subscribe
9,789,090 Treatment using dantrolene ➤ Subscribe
9,271,964 Treatment using dantrolene ➤ Subscribe
8,685,460 Treatment using dantrolene ➤ Subscribe
Patent No. Title Estimated Patent Expiration

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International Patents Family Members for US Patent 7,758,890

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Japan 2007525439 ➤ Subscribe
Japan 4880449 ➤ Subscribe
European Patent Office 1603513 ➤ Subscribe
European Patent Office 1435781 ➤ Subscribe
Canada 2516667 ➤ Subscribe
Australia 2004262507 ➤ Subscribe
World Intellectual Property Organization (WIPO) 03000057 ➤ Subscribe
World Intellectual Property Organization (WIPO) 2005013919 ➤ Subscribe
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving leading biopharmaceutical companies globally:

Farmers Insurance
Accenture
US Army
UBS
Johnson and Johnson
Merck
Julphar
Federal Trade Commission
Dow

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