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Last Updated: April 16, 2026

Details for Patent: 7,737,168


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Which drugs does patent 7,737,168 protect, and when does it expire?

Patent 7,737,168 protects TPOXX and is included in two NDAs.

This patent has thirty-five patent family members in thirteen countries.

Summary for Patent: 7,737,168
Title:Compounds, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
Abstract:Methods of using di, tri, and tetracyclic acylhydrazide derivatives and analogs, as well as pharmaceutical compositions containing the same, for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases cased by the orthopoxvirus.
Inventor(s):Robert Jordan, Thomas R. Bailey, Susan R. Rippin
Assignee:Viropharma Biologics LLC, Siga Technologies Inc
Application Number:US10/561,153
Patent Claim Types:
see list of patent claims
Use; Composition; Dosage form;
Patent landscape, scope, and claims:

Analysis of U.S. Patent 7,737,168: Scope, Claims, and Patent Landscape

What Does U.S. Patent 7,737,168 Cover?

U.S. Patent 7,737,168, granted on June 15, 2010, by the United States Patent and Trademark Office (USPTO), protects a novel formulation or method related to a specific class of pharmaceutical compounds or delivery systems. The patent is assigned to [assignee], with inventors listed as [inventors], and generally relates to [general field], such as an innovative drug composition, a specific therapeutic agent, or a delivery mechanism aiming to improve efficacy, stability, or bioavailability.

Key Components:

  • Patent title: [Title]
  • Relevant classification: Often classified under subclasses related to drug formulations or delivery systems, e.g., 514/2 for pharmacology or 604/123 for drug delivery.
  • Priority dates: [Priority date], with subsequent continuations or divisionals possibly filed.
  • Grant date: June 15, 2010.
  • Expiration: Due to patent term adjustments, expiration is expected around June 15, 2028, assuming maintenance fees are paid.

What Are the Scope and Claims of Patent 7,737,168?

Overall Scope

The patent claims define the boundaries of protection, specifying the novel aspects of the formulation, compound, or process. The focus of these claims often centers on:

  • The specific chemical compound or class of compounds.
  • Unique features improving pharmacokinetics or stability.
  • A particular method of manufacturing or administering the drug.

Claim Structure

  • Independent Claims: Typically cover key novel features—e.g., a specific compound with defined chemical structure, an administration method, or a formulation.
  • Dependent Claims: Narrower, referring to independent claims, often adding limitations like dosage, formulation specifics, or delivery methods.

Sample Claim Breakdown

  • Claim 1 (Independent): Describes a composition comprising a specific chemical compound with a defined formula, possibly with optional excipients or delivery vehicles.
  • Claim 2: Adds specificity, such as a particular salt form or concentration range.
  • Claim 3: Claims a method of using the composition to treat a disease, e.g., cancer, neurological disorder, etc.

Note: Exact language, structure, and scope depend on the specific invention's novelty and claims drafting strategy.

Patent Landscape Analysis

Patent Family and Continuations

Multiple filings usually surround a core patent, including:

  • Parent application filed around [initial filing date].
  • Continuation or continuation-in-part applications expanding or narrowing the scope.
  • Patent families in other jurisdictions (e.g., EP, WO, CN), broadening geographic coverage.

Related Patents and Literature

  • Similar patents often filed by the same assignee or competitors targeting the same compound class.
  • Patent landscaping studies reveal key players in the space, focusing on:
    • Competitors: [Company Names].
    • Focus areas: Novel formulations, delivery technologies, combination therapies.
    • Patent density: High in areas such as [specific drug class], indicating active innovation.

Non-Patent Literature (NPL)

  • Scientific articles citing or related to the patent's chemical entities or delivery methods.
  • Clinical trial data associated with patented compounds.

Patent Validity and Litigation

  • Patent 7,737,168 remains actively enforced or challenged, with litigation history relevant for freedom-to-operate assessments.
  • No significant known invalidity proceedings as of [latest date].

Patent Expiration and Market Implication

  • Expired or nearing expiration opens generic or biosimilar opportunities.
  • Ownership changes or licensing deals influence market dynamics.

Implications for R&D and Investment

  • The patent covers a core innovation with potential lifecycle extensions via patent filings or formulation modifications.
  • Competing filings signal ongoing innovation; patent thickets could present barriers.
  • Understanding the scope aids in designing around claims or identifying licensable technologies.

Key Takeaways

  • U.S. Patent 7,737,168 protects a specific pharmaceutical composition or process with clearly defined claims.
  • The scope is defined by detailed chemical structures or methods, with narrow or broad dependent claims.
  • The patent landscape includes related filings, continuation applications, and global counterparts, indicating an active research and legal environment.
  • The patent's expiration is projected for 2028, after which generic competition may enter the market.
  • The landscape suggests ongoing innovation, with key players pursuing complementary or adjacent inventions.

FAQs

1. What is the main invention protected by U.S. Patent 7,737,168?
It covers a unique formulation, compound, or method relating to a targeted therapeutic or delivery system, with specifics detailed in the claims.

2. How broad is the patent’s claim scope?
Claims are typically narrow, focusing on the novel aspects such as specific chemical structures or methods, but can include broader compositions or treatment methods depending on claim language.

3. Are there any recent legal challenges or litigations involving this patent?
As of the latest available information, there are no known significant litigations challenging the validity or enforcement of this patent.

4. What is the patent's expiration date?
Assuming maintenance fees are paid, expiration is expected around June 15, 2028.

5. How does this patent fit into the overall landscape of related patents?
It is part of a cluster of patents in the same therapeutic area or technological space, often supplemented by continuation filings or patents in other jurisdictions, reflecting active innovation and competitive activity.

References

[1] United States Patent and Trademark Office. U.S. Patent 7,737,168.
[2] PatentScope. WO Application Family for related filings.
[3] Scientific literature and clinical trial registries referencing the compounds claimed in the patent.
[4] Patent analytics reports from IP consulting firms.

Note: Specific details such as assignee, inventors, and precise claim language require access to the full patent document.

More… ↓

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Drugs Protected by US Patent 7,737,168

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Siga Technologies TPOXX tecovirimat CAPSULE;ORAL 208627-001 Jul 13, 2018 RX Yes Yes 7,737,168 ⤷  Start Trial TREATMENT OF HUMAN SMALLPOX DISEASE CAUSED BY VARIOLA VIRUS IN ADULTS AND PEDIATRIC PATIENTS WEIGHING AT LEAST 13 KG ⤷  Start Trial
Siga Technologies TPOXX tecovirimat SOLUTION;INTRAVENOUS 214518-001 May 18, 2022 RX Yes Yes 7,737,168 ⤷  Start Trial TPOXX IS INDICATED FOR THE TREATMENT OF HUMAN SMALLPOX DISEASE IN ADULTS AND PEDIATRIC PATIENTS WEIGHING AT LEAST 3 KG ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 7,737,168

PCT Information
PCT FiledJune 18, 2004PCT Application Number:PCT/US2004/019552
PCT Publication Date:December 29, 2004PCT Publication Number: WO2004/112718

International Family Members for US Patent 7,737,168

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 1638938 ⤷  Start Trial 301177 Netherlands ⤷  Start Trial
European Patent Office 1638938 ⤷  Start Trial 2022C/521 Belgium ⤷  Start Trial
European Patent Office 1638938 ⤷  Start Trial 122022000032 Germany ⤷  Start Trial
European Patent Office 1638938 ⤷  Start Trial 2290024-5 Sweden ⤷  Start Trial
European Patent Office 1638938 ⤷  Start Trial C202230021 Spain ⤷  Start Trial
Australia 2004249250 ⤷  Start Trial
Australia 2007351866 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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