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Serving leading biopharmaceutical companies globally:

Merck
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Mallinckrodt
Teva
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Farmers Insurance
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Generated: December 15, 2017

DrugPatentWatch Database Preview

Details for Patent: 7,514,444

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Which drugs does patent 7,514,444 protect, and when does it expire?


Patent 7,514,444 protects IMBRUVICA and is included in one NDA.

This patent has one hundred and fifteen patent family members in twenty-six countries.

Summary for Patent: 7,514,444

Title:Inhibitors of bruton's tyrosine kinase
Abstract: Disclosed herein are compounds that form covalent bonds with Bruton's tyrosine kinase (Btk). Also described are irreversible inhibitors of Btk. Methods for the preparation of the compounds are disclosed. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the Btk inhibitors are disclosed, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.
Inventor(s): Honigberg; Lee (San Francisco, CA), Verner; Erik (San Mateo, CA), Pan; Zhengying (Apharetta, GA)
Assignee: Pharmacyclics, Inc. (Sunnyvale, CA)
Application Number:11/617,645
Patent Claim Types:
see list of patent claims
Compound; Composition;

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Patent Submitted Product Substance Delist Req. Patented / Exclusive Use
Pharmacyclics IncIMBRUVICAibrutinibCAPSULE;ORAL205552-001Nov 13, 2013RXYesYes► Subscribe► Subscribe► SubscribeYY
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Non-Orange Book Patents for Patent: 7,514,444

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
8,735,403Inhibitors of Bruton's tyrosine kinase► Subscribe
8,697,711Inhibitors of bruton'S tyrosine kinase► Subscribe
8,232,280Inhibitors of bruton'S tyrosine kinase► Subscribe
8,741,908Inhibitors of bruton's tyrosine kinase► Subscribe
9,133,201Inhibitors of Bruton's tyrosine kinase► Subscribe
9,133,202Inhibitors of Bruton's tyrosine kinase► Subscribe
8,658,653Inhibitors of Bruton's tyrosine kinase► Subscribe
9,133,198Inhibitors of bruton'S tyrosine kinase► Subscribe
9,212,185Inhibitors of Bruton's tyrosine kinase► Subscribe
9,127,012Inhibitors of bruton's tyrosine kinase► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Because of the complexity of determining patent expiration dates it is advisable to have patent counsel verify freedom to operate.

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International Patent Family for Patent: 7,514,444

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
BrazilPI0810086► Subscribe
Canada2663116► Subscribe
Canada2681756► Subscribe
Canada2847852► Subscribe
Canada2874756► Subscribe
China101610676► Subscribe
China101674834► Subscribe
China101805341► Subscribe
China102746305► Subscribe
China102887900► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Serving leading biopharmaceutical companies globally:

McKinsey
Teva
Cerilliant
Baxter
Colorcon
Medtronic
Mallinckrodt
Johnson and Johnson
Fuji
Queensland Health

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

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