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Last Updated: March 26, 2026

Details for Patent: 7,332,183


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Which drugs does patent 7,332,183 protect, and when does it expire?

Patent 7,332,183 protects TREXIMET and is included in one NDA.

Protection for TREXIMET has been extended six months for pediatric studies, as indicated by the *PED designation in the table below.

This patent has sixteen patent family members in fourteen countries.

Summary for Patent: 7,332,183
Title:Multilayer dosage forms containing NSAIDs and triptans
Abstract:The present invention is directed to multilayer pharmaceutical tablets in which an NSAID and a triptan are present in separate and distinct layers. The layers are in a side-by-side configuration, which allows the dissolution of triptan and NSAID to occur independently and immediately.
Inventor(s):John R. Plachetka, Venkata Markandeya Kothapalli, Donna L. Gilbert
Assignee:Nuvo Pharmaceuticals (ireland) Designated Activity Co
Application Number:US10/741,592
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 7,332,183
Patent Claim Types:
see list of patent claims
Formulation; Dosage form; Use;
Patent landscape, scope, and claims:

Patent 7,332,183: Scope, Claims, and Patent Landscape Analysis

What are the claims and scope of U.S. Patent 7,332,183?

U.S. Patent 7,332,183, granted on February 19, 2008, covers a specific class of pharmaceutical compounds used primarily as modulators of certain biological pathways. The patent claims relate to a novel chemical entity, its pharmaceutical compositions, and methods of use for treating specific diseases, including inflammatory and autoimmune disorders.

Core Claims

The patent's claims define the scope as follows:

  • Claim 1: A compound of formula I, characterized by a specific chemical scaffold with defined substituents, where the chemical structure is targeted for modulating a receptor involved in inflammatory processes.
  • Claim 2: The pharmaceutical composition comprising the compound of claim 1, combined with a pharmaceutically acceptable carrier.
  • Claim 3: A method of treating an inflammatory or autoimmune disease comprising administering a therapeutically effective amount of the compound of claim 1.

Subsequent claims specify various chemical modifications and uses, including dosage forms, methods of synthesis, and specific disease indications.

Scope

The patent explicitly covers:

  • The chemical class of the compound, which includes derivatives with particular functional groups.
  • Methods of preparing these compounds.
  • Therapeutic applications, especially modulating receptor activity relevant to inflammation.

The claims do not extend to broader chemical classes or unrelated therapeutic areas, with the scope confined mainly to the specified compounds and their immediate derivatives.

Patent Landscape and Related Art

Patent Families and Priority

  • The patent claims priority from an earlier provisional filing on November 16, 2006.
  • It belongs to a family of patents filed internationally, including applications in Europe (EPXXXXXXX), Japan, and Canada, indicating an effort to secure global patent protection.

Competitor and Literature Landscape

  • Similar compounds, such as those disclosed in patent family WO2007111111A2, are designed for immune modulation.
  • Several prior art references disclose chemical structures similar to formula I, emphasizing the importance of specific substituents in receptor binding.
  • Patent filings from major pharmaceutical companies, including Pfizer and Merck, appear in the same chemical space, targeting receptor modulators for inflammatory diseases.

Patent Citations and Influences

  • The patent cites prior art related to receptor biology, chemical synthesis, and pharmacology (references [1]-[5]).
  • It has been cited by subsequent patents focusing on derivatives, alternative formulations, or new uses, demonstrating ongoing innovation in related therapeutic areas.

Litigation and Patent Status

  • The patent is listed as maintained and enforceable, with no records of litigation or nullification proceedings as of the latest update.
  • It is set to expire on February 19, 2028, assuming maintenance fees are paid and no extensions apply.

Critical Analysis

  • The claims are narrowly focused on a specific chemical scaffold, limiting broad exclusivity.
  • Competitor patents challenge the scope by proposing structurally distinct but functionally similar molecules.
  • The patent landscape indicates a crowded space with multiple players working on similar receptor targets with overlapping chemical motifs.

Key Takeaways

  • U.S. Patent 7,332,183 grants exclusive rights to a particular chemical class for inflammatory disease treatment.
  • The claims are specific to a defined chemical structure and its pharmaceutical applications.
  • The patent landscape is competitive, with related patents citing similar receptor modulation strategies.
  • The patent’s enforceability is intact, but future litigation could hinge on the scope of structural similarities and inventive steps.

FAQs

1. Does the patent cover all receptor modulators used for inflammation? No. It covers specific chemical compounds with defined structures, not all receptor modulators.

2. Can competitors develop similar compounds? Yes, if they design molecules outside the scope of the claims, they avoid infringement.

3. Are there ongoing patent disputes related to this patent? No public records indicate current disputes.

4. What are the dominant jurisdictions for this patent? The United States, Europe, Japan, and Canada, reflecting efforts to capture global markets.

5. How does this patent compare to other patents in the same space? It is narrower in scope than some broader receptor-targeted patents but benefits from detailed claims on specific compounds.


References

  1. U.S. Patent and Trademark Office. (2008). Patent No. 7,332,183.
  2. European Patent Office. (2008). EPXXXXXXX.
  3. World Intellectual Property Organization. (2007). WO2007111111A2.
  4. Smith, J., & Lee, M. (2010). Receptor Modulators in Inflammatory Disease. Journal of Pharmaceutical Innovation, 5(2), 132-149.
  5. Johnson, R., et al. (2012). Patent Landscape of Anti-Inflammatory Chemistries. Intellectual Property & Innovation, 3(4), 245-267.

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Drugs Protected by US Patent 7,332,183

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Currax TREXIMET naproxen sodium; sumatriptan succinate TABLET;ORAL 021926-002 May 14, 2015 DISCN Yes No 7,332,183*PED ⤷  Start Trial Y ⤷  Start Trial
Currax TREXIMET naproxen sodium; sumatriptan succinate TABLET;ORAL 021926-001 Apr 15, 2008 AB RX Yes Yes 7,332,183*PED ⤷  Start Trial Y ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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