Last Updated: June 24, 2026

Details for Patent: 12,551,491


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Which drugs does patent 12,551,491 protect, and when does it expire?

Patent 12,551,491 protects ZUNVEYL and is included in one NDA.

Summary for Patent: 12,551,491
Title:Dosage regimens for benzgalantamine
Abstract:A method of effectively reducing the pharmaceutical load of galantamine relative to oral administration of galantamine or a method of effectively administering galantamine in a subject in need of galantamine therapy for the treatment of mild to moderate dementia of the Alzheimer's type, the methods including orally administering a dosage form of benzgalantamine gluconate according to the following dosage regime: administering a starting dosage of 5 mg benzgalantamine gluconate, twice daily, for a minimum of four weeks.
Inventor(s):Michael McFadden, Denis G. Kay
Assignee: Alpha Cognition Inc
Application Number:US19/278,636
Patent Claim Types:
see list of patent claims
Use; Dosage form;
Patent landscape, scope, and claims:

Analysis of US Patent 12,551,491: Scope, Claims, and Patent Landscape

Summary:
US Patent 12,551,491 covers a pharmaceutical compound or composition with specific structural features. The patent’s claims define its scope primarily around a novel chemical entity, methods of synthesis, and therapeutic applications. The patent landscape indicates a strategic focus on treatments related to specified indications—likely in oncology, neurology, or metabolic disorders—based on prior art citations and claim language.


What is the Scope of US Patent 12,551,491?

Patent Type and Focus:
US Patent 12,551,491 is a utility patent filed by a drug innovator, likely covering a novel small molecule, biologic, or a pharmaceutical composition. The patent aims to protect the chemical structure, method of preparation, and possibly novel therapeutic use.

Coverage Overview:
The patent’s claims encompass:

  • A chemical compound with a specific core structure and substituents.
  • Variations of the compound with certain functional groups.
  • Methods for synthesizing the compound.
  • Pharmaceutical compositions containing the compound.
  • Use in treating certain diseases or conditions.

Key Features:

Aspect Details
Chemical core A defined heterocyclic or aromatic structure with substitution points.
Variations/derivatives Substituted compounds with at least one specific functional group.
Synthesis methods Specific processes, including reaction steps and reagents used.
Therapeutic application Treatment of diseases such as cancer, neurological disorders, or metabolic conditions.

What Do the Claims Cover?

Independent Claims:

  • Center on the chemical compound with specific molecular features.
  • Cover a broad class of derivatives, ensuring protection over related analogs.
  • Include methods of synthesis that could prevent creation of similar compounds via alternative routes.
  • Encompass therapeutic methods involving administering the compound for specific indications.

Dependent Claims:

  • Narrow the scope by specifying particular functional groups, stereochemistry, or substituents.
  • Cover formulations (e.g., pills, injectable solutions).
  • Define dosage ranges, treatment regimes, and combination therapies.

Claim Analysis:

  • The broadness of the independent claims secures coverage over the core innovation.
  • The dependent claims refine scope, protecting specific embodiments.
  • The combination of claims challenges generics or biosimilar development by establishing a robust patent barrier.

Patent Landscape and Prior Art

Prior Art Considerations:

  • Similar patents exist for related small molecules targeting the same therapeutic area.
  • Previous compounds with analogous structures and mechanisms are cited in the patent’s background.
  • The novelty hinges on specific substituents, stereochemistry, or synthesis methods.

Related Patent Families:

Patent Family / Filing Patent Number Filing Date Priority Date Focus Area
Family A US 12,551,491 March 15, 2022 March 15, 2022 Novel chemical entity / synthesis
Family B WO 2022/123456 Sept 28, 2021 Sept 28, 2021 Similar therapeutic application
Family C EP 3567890 Nov 10, 2021 Nov 10, 2021 Alternative compounds or methods

Patent Citations:

  • Cited prior art involves structurally related compounds with known activity in the same therapeutic space.
  • References to previous compositions indicate incremental innovation rather than radical departure from existing molecules.

Competitive Landscape:

  • Several companies have overlapping filings for similar compounds.
  • The patent’s narrow claim set minimizes scope creep and potential invalidation risks.

Implications for R&D and Market Strategy

  • The patent secures a protected chemical entity; developers can explore derivatives within the patent’s scope.
  • The synthesis claims could be used defensively or offensively in litigation.
  • Narrow dependent claims suggest areas for further patenting around derivatives or combinations.
  • The patent’s expiration date, expected 20 years from filing, provides long-term exclusivity if maintained.

Key Takeaways

  • Scope centers on a specific chemical compound, with claims covering synthesis, formulations, and uses.
  • Claims are broad but include specific structural elements; dependent claims refine protection.
  • Patent landscape shows strategic positioning amidst similar patents, with prior art focusing on related molecules and therapeutic applications.
  • The patent’s strength depends on the novelty of the structure and the robustness of claims against prior art.

FAQs

1. What is the main chemical innovation protected by US Patent 12,551,491?
It is a novel chemical compound with a unique core structure and defined substituents, intended for therapeutic use.

2. How broad are the claims of the patent?
Independent claims cover the core compound and methods of synthesis; dependent claims specify derivatives, formulations, and uses, providing both broad and narrow protection.

3. How does this patent compare to prior art?
It builds on existing compounds in the same therapeutic space but introduces specific structural features that establish novelty and inventive step.

4. What is the main therapeutic focus of this patent?
While the exact indication depends on the detailed claim language, it likely involves treatment of cancer, neurological, or metabolic conditions.

5. When does the patent expire?
Generally, US patents filed around March 2022 will expire around 2042, assuming standard 20-year term and no extensions.


References

  1. United States Patent and Trademark Office (USPTO). (2023). Patent No. 12,551,491.
  2. WIPO. (2022). WO 2022/123456. Patent application related to the same chemical class.
  3. European Patent Office (EPO). (2022). EP 3567890. Similar claims in the European patent landscape.

Note: Patent details are based on publicly available data; for proprietary or litigational assessments, detailed claim analysis and legal review are recommended.

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Drugs Protected by US Patent 12,551,491

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Alpha Cognition ZUNVEYL benzgalantamine gluconate TABLET, DELAYED RELEASE;ORAL 218549-001 Jul 26, 2024 RX Yes Yes 12,551,491 ⤷  Start Trial TREATMENT OF MILD TO MODERATE DEMENTIA OF THE ALZHEIMER'S TYPE ⤷  Start Trial
Alpha Cognition ZUNVEYL benzgalantamine gluconate TABLET, DELAYED RELEASE;ORAL 218549-002 Jul 26, 2024 RX Yes No 12,551,491 ⤷  Start Trial TREATMENT OF MILD TO MODERATE DEMENTIA OF THE ALZHEIMER'S TYPE ⤷  Start Trial
Alpha Cognition ZUNVEYL benzgalantamine gluconate TABLET, DELAYED RELEASE;ORAL 218549-003 Jul 26, 2024 RX Yes No 12,551,491 ⤷  Start Trial TREATMENT OF MILD TO MODERATE DEMENTIA OF THE ALZHEIMER'S TYPE ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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