Details for Patent: 12,281,113
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Which drugs does patent 12,281,113 protect, and when does it expire?
Patent 12,281,113 protects KRAZATI and is included in one NDA.
This patent has thirteen patent family members in thirteen countries.
Summary for Patent: 12,281,113
| Title: | Crystalline forms of a KRas G12C inhibitor |
| Abstract: | The present invention relates to crystalline forms of a KRas G12C inhibitor and salt thereof. In particular, the present invention relates to crystalline forms of the KRas G12C inhibitor 2-[(2S)-4-[7-(8-chloro-1-naphthyl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-yl]-1-(2-fluoroprop-2-enoyl)piperazin-2-yl]acetonitrile, pharmaceutical compositions comprising the crystalline forms, processes for preparing the crystalline forms and methods of use thereof. |
| Inventor(s): | Patricia Andres, Samuel Andrew, Cheng Yi Chen, Susana Del Rio Gancedo, Tawfik Gharbaoui, Jennifer Nelson |
| Assignee: | Mirati Therapeutics Inc |
| Application Number: | US18/782,879 |
|
Patent Claim Types: see list of patent claims | Composition; Compound; |
Drugs Protected by US Patent 12,281,113
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Bristol | KRAZATI | adagrasib | TABLET;ORAL | 216340-001 | Dec 12, 2022 | RX | Yes | Yes | ⤷ Start Trial | ⤷ Start Trial | Y | Y | ⤷ Start Trial | |||
| >Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
International Family Members for US Patent 12,281,113
| Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
|---|---|---|---|---|---|
| Australia | 2021340716 | ⤷ Start Trial | |||
| Brazil | 112023004569 | ⤷ Start Trial | |||
| Canada | 3190944 | ⤷ Start Trial | |||
| Chile | 2023000693 | ⤷ Start Trial | |||
| China | 116601151 | ⤷ Start Trial | |||
| Colombia | 2023004141 | ⤷ Start Trial | |||
| European Patent Office | 4210833 | ⤷ Start Trial | |||
| >Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |
