Last Updated: November 10, 2026

Details for Patent: 12,234,210

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Which drugs does patent 12,234,210 protect, and when does it expire?

Patent 12,234,210 protects OGSIVEO and is included in one NDA.

This patent has sixteen patent family members in fourteen countries.

Summary for Patent: 12,234,210
Title:Synthesis of nirogacestat
Abstract:The present disclosures are directed to processes for synthesizing (S)-2-(((S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide (“nirogacestat”).
Inventor(s):Kristin Patterson, Mark Hatcher
Assignee: SpringWorks Therapeutics Inc
Application Number:US18/304,202
Patent Claim Types:
see list of patent claims
Use; Composition; Compound;

Drugs Protected by US Patent 12,234,210

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Springworks OGSIVEO nirogacestat hydrobromide TABLET;ORAL 217677-001 Nov 27, 2023 DISCN Yes No 12,234,210 ⤷  Start Trial Y ⤷  Start Trial
Springworks OGSIVEO nirogacestat hydrobromide TABLET;ORAL 217677-002 Apr 4, 2024 RX Yes No 12,234,210 ⤷  Start Trial Y ⤷  Start Trial
Springworks OGSIVEO nirogacestat hydrobromide TABLET;ORAL 217677-003 Apr 4, 2024 RX Yes Yes 12,234,210 ⤷  Start Trial Y ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 12,234,210

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina 126961 ⤷  Start Trial
Australia 2022339841 ⤷  Start Trial
Canada 3230245 ⤷  Start Trial
Chile 2024000608 ⤷  Start Trial
Chile 2025003464 ⤷  Start Trial
China 118043305 ⤷  Start Trial
Colombia 2024002573 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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