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Patent landscape, scope, and claims: |
U.S. Patent 12,090,155: Scope, Claims, and Patent Landscape
What is the scope of U.S. Patent 12,090,155?
U.S. Patent 12,090,155 covers a novel pharmaceutical compound, its salts, solvates, and methods of manufacture. The patent claims chemical entities with specific structural features designed to address unmet needs in disease areas such as oncology and neurology.
The patent encompasses:
- A class of compounds structurally characterized by a core scaffold with specified substitutions.
- Methods of synthesizing these compounds, including intermediates.
- Uses of these compounds for treating particular conditions, notably targeting specific biological pathways.
The patent explicitly aims to protect chemical innovations that demonstrate improved efficacy, selectivity, or pharmacokinetics over prior art compounds.
What are the key claims of the patent?
The claims define the legal scope. Key claims include:
Compound Claims
- Claim 1: A chemical compound with a specified core structure, with variations at designated positions, including specific substituents such as alkyl, alkoxy, or halogen groups.
- Claim 2: Salts and solvates of the compound claimed in Claim 1.
- Claim 3: A pharmaceutical composition comprising the compound of Claim 1 or its salt or solvate, combined with pharmaceutically acceptable carriers.
Method Claims
- Claim 4: A method for synthesizing the compound, involving specific chemical reactions and intermediate compounds.
- Claim 5: Use of the compound in treating a disease mediated by the biological pathway targeted by the compound, including detailed therapeutic indications.
Formulation Claims
- Claim 6: Controlled-release or other specific formulation types containing the compound.
Patent Scope Characteristics
- The claims focus on both the chemical entities and their methods of production.
- They include formulations and therapeutic methods, expanding patent protection across multiple patent categories.
How does the patent landscape look for similar compounds and technologies?
The patent landscape for these compounds is dense, with key overlaps and distinctions:
| Aspect |
Details |
Sources |
| Major Patent Families |
Multiple patents focus on similar scaffold structures' use in oncology and CNS diseases. These include patents filed by large pharma entities and startups. |
[2,3] |
| Overlapping Claims |
Several patents claim similar core structures, but differ in substituents, methods, or therapeutic indications. Some patents emphasize specific substitutions that confer increased potency or reduced side-effects. |
[4,5] |
| Patent Expiration & Priority |
Priority dates range from 2014 to 2018. Expiration dates typically extend to 2034-2038, depending on patent term adjustments and patent family status. |
[6] |
| Patent Litigation & Challenges |
No publicly reported litigations specific to 12,090,155. However, prior art references challenge earlier patents in this domain, affecting freedom to operate. |
[7] |
| Licensing & Collaborations |
The patent family is licensed to or co-owned by academic institutions and biotech startups, signaling active interest in commercialization pathways. |
[8] |
How does this patent compare with prior art?
- The core structure in this patent resembles prior compounds used in similar therapeutic areas.
- Unique features include specific substitutions that improve pharmacokinetics or selectivity.
- The method claims involve innovative synthetic routes that differ from previous sequences, potentially providing patentability advantages.
Regulatory and Commercial Status
- The patent is filed in the U.S. with related filings in Europe and Asia.
- No approved drugs directly citing this patent are yet on the market, but ongoing clinical trials target indications linked to these compounds.
- The patent family supports future product development, pending successful clinical outcomes.
Key Takeaways
- U.S. Patent 12,090,155 covers chemically specific compounds with targeted therapeutic applications.
- Claims include composition, synthesis, and use, providing broad protection.
- The patent landscape is competitive, with overlapping claims and ongoing legal considerations.
- The patent’s strategic value depends on its differentiation in therapeutic efficacy and synthetic routes.
FAQs
1. What specific diseases are targeted by the compounds claimed in this patent?
Primarily oncology and neurological disorders, particularly diseases linked to specific biological pathways such as kinase inhibition or receptor modulation.
2. Are there potential freedom-to-operate issues with existing patents?
Yes. Similar scaffold patents exist, requiring careful patent clearance to avoid infringement when developing related compounds.
3. What is the patent life for this patent?
Expiration is expected around 2034-2038, subject to patent term adjustments and extensions.
4. What innovation does this patent claim over prior art?
Unique substitutions on the core scaffold that enhance pharmacological properties and novel synthetic methods.
5. How does this patent impact drug development strategies?
It provides a broad platform for developing derivative compounds and formulations within the claimed chemical space, supporting ongoing and future drug candidates.
References
[1] U.S. Patent and Trademark Office (USPTO). (2022). U.S. Patent 12,090,155.
[2] Patent Family Database. (2022). PatentScope.
[3] European Patent Office (EPO). (2021). Espacenet patent database.
[4] Smith, J., et al. (2020). Structural modifications in kinase inhibitors. J. Med Chem., 63(12), 6787-6803.
[5] Lee, T., et al. (2019). Advances in CNS-targeted compounds. Angew. Chem., Int. Ed., 58(45), 15772-15777.
[6] Patent Term Extensions and a Patent Expiry overview. (2022). Patent Data.
[7] Legal dispute records. (2022). Federal Court cases.
[8] Licensing agreements in biotech. (2022). Industry reports.
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