Last Updated: November 8, 2026

Details for Patent: 12,042,494

Name: Drug Patent Intelligence for US Patent 12042494
Creator: DrugPatentWatch
License: https://www.drugpatentwatch.com/terms.php

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Which drugs does patent 12,042,494 protect, and when does it expire?

Patent 12,042,494 protects AKYNZEO and is included in one NDA.

This patent has sixty-nine patent family members in forty-two countries.

Summary for Patent: 12,042,494

Title:	Compositions and methods for treating centrally mediated nausea and vomiting
Abstract:	Provided are compositions and methods for treating or preventing nausea and vomiting in patients undergoing chemotherapy, radiotherapy, or surgery.
Inventor(s):	Fabio Trento, Sergio Cantoreggi, Giorgia Rossi, Roberta Cannella, Daniele Bonadeo
Assignee:	Helsinn Healthcare SA
Application Number:	US18/082,737
Patent Claim Types: see list of patent claims	Use; Dosage form;

Drugs Protected by US Patent 12,042,494

Glossary

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
Helsinn Hlthcare	AKYNZEO	netupitant; palonosetron hydrochloride	CAPSULE;ORAL	205718-001	Oct 10, 2014		RX	Yes	Yes	⤷ Start Trial	⤷ Start Trial	Y			METHOD OF TREATING EMESIS	⤷ Start Trial
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

International Family Members for US Patent 12,042,494

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Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
African Regional IP Organization (ARIPO)	3083	⤷ Start Trial
Australia	2010320598	⤷ Start Trial
Brazil	112012011485	⤷ Start Trial
Canada	2778301	⤷ Start Trial
Chile	2012001276	⤷ Start Trial
China	102655864	⤷ Start Trial
China	104856998	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration	>Supplementary Protection Certificate	>SPC Country	>SPC Expiration

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