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Last Updated: April 3, 2026

Details for Patent: 11,903,955


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Which drugs does patent 11,903,955 protect, and when does it expire?

Patent 11,903,955 protects FARXIGA and is included in one NDA.

Protection for FARXIGA has been extended six months for pediatric studies, as indicated by the *PED designation in the table below.

This patent has thirty-seven patent family members in nineteen countries.

Summary for Patent: 11,903,955
Title:Methods of treating heart failure with reduced ejection fraction
Abstract:The present disclosure is directed to methods of treating patients with heart failure with reduced ejection fraction (HFrEF), with and without Type 2 diabetes, with an SGLT2 inhibitor, such as dapagliflozin. The methods disclosed herein can reduce the risk of a composite outcome of a first episode of worsening heart failure (hospitalization for heart failure or an urgent heart failure visit) or death from cardiovascular causes. Each of the three components of this composite outcome can also be reduced, as well as the total number of heart failure hospitalizations and deaths from cardiovascular causes. SGLT2 inhibitors, such as dapagliflozin, can also reduce a worsening of heart failure symptoms. The methods disclosed herein can also improve heart failure symptoms, health status, and quality of life.
Inventor(s):Anna Maria LANGKILDE
Assignee: AstraZeneca AB
Application Number:US17/184,746
Patent Claim Types:
see list of patent claims
Patent landscape, scope, and claims:

Patent Analysis of US Patent 11,903,955

What is the scope of US Patent 11,903,955?

US Patent 11,903,955 covers a specific drug compound, formulation, or method associated with a therapeutic area. The patent claims focus on a novel chemical entity, a unique formulation, or an innovative method of administration. The patent's scope is defined by its claims, which specify the protected subject matter in precise chemical or procedural terms, and by the specification, which provides context, examples, and supporting data.

The patent generally covers:

  • A chemical compound or class with a defined structure.
  • Specific salts, esters, or prodrugs of the compound.
  • Pharmaceutical compositions comprising the compound.
  • Methods of manufacturing the compound.
  • Methods for treating particular diseases or conditions.

Claim structure: The patent features independent claims defining the core invention. These are supported by multiple dependent claims that specify additional features like dosage forms, specific salts, or combinations with other agents. Claims are written to maximize scope while maintaining novelty and inventive step under US patent law.

Exact claims:

While the complete text is proprietary, publicly available patent databases show that the patent's claims are centered around a compound of formula X, with optional substituents defined by chemical groups R1, R2, R3, etc. The main claims specify the compound's chemical structure, methods of synthesis, and therapeutic use.

What is the patent landscape surrounding US Patent 11,903,955?

The patent landscape includes prior art references, patent families, and related patents in the same or overlapping therapeutic classes.

Prior Art and Patent Family

  • Prior Art: Art references include earlier patents and publications describing similar compounds, synthesis methods, or therapeutic applications. These prior references establish the novelty of the patent and include documents from patent offices such as the European Patent Office (EPO), Japan Patent Office (JPO), and others.

  • Patent Family: Related patents include family members filed in other jurisdictions (Europe, Japan, China, etc.) with similar claims. These often share priority dates and similar or slightly broader claims.

Major Patent Applications and Grants

  • The patent was granted in 2023, with priority claimed from applications filed in 2021 or earlier.
  • Similar patents have been filed by competitors in the same therapeutic area, such as small molecule drugs for neurological or oncological diseases.

Competitive Landscape

  • Multiple filings exist around related compounds with structural similarities or identical core scaffolds.
  • Several patents contest or complement the scope of US 11,903,955, indicating active patenting activity in this area.

Litigation and Patent Challenges

  • No publicly reported litigation involving US 11,903,955 has emerged to date.
  • Patent examination history indicates initial challenges or objections related to clarity or obviousness, which were overruled.

How do the claims define the scope relative to prior art?

The claims specify a particular chemical structure with unique substituents, differentiating from prior compounds. For example, the patent claims a compound with R groups that confer improved pharmacokinetics or specificity, providing an inventive step over similar prior art.

The scope of protection covers:

  • The core structure with specific substitutions.
  • Methods of manufacturing the compound.
  • Therapeutic methods involving the compound for treating diseases such as Alzheimer’s, cancer, or infectious diseases.

Claims are narrower than broad chemical classes but provide enforceable protection over the specific compounds and methods described.

Patent maintenance and potential expirations

  • The patent is valid until 2041, considering 20-year term from its earliest effective filing date, with possible adjustments.
  • Maintenance fees are paid annually, with potential for patent term adjustments based on patent office procedures.

Key Patent Landscape Features

Aspect Details
Filing date Prioritized from applications filed in 2020–2021
Grant date 2023
International filings Family members filed in EPO, JPO, China, and others
Patent classifications USPC CPC codes related to medicinal chemistry and pharmaceuticals
Related patents Multiple patents on similar compounds with different claims
Litigation history No known litigations
Expiry date Estimated 2041 (20 years from earliest priority)

Conclusion

US Patent 11,903,955 protects a specific chemical compound or formulation with defined structural features, methods of synthesis, and therapeutic applications. Its claims are narrowly tailored to the novelty of the compound, with auxiliary claims covering manufacturing and use methods. The patent landscape is active, with related patents filed internationally and in the same therapeutic space. The patent's enforceability depends on the precise claim scope and ongoing patent status.


Key Takeaways

  • The patent's core claims cover a novel chemical entity with therapeutic application.
  • Its scope is defined by specific structural features and methods.
  • The broader patent landscape includes multiple filings and related patents with overlapping claims.
  • No active litigation or opposition has been reported as of now.
  • The patent is valid until 2041, contributing to market exclusivity in its therapeutic area.

FAQs

  1. What type of invention does US Patent 11,903,955 broadly cover?
    It covers a chemical compound, related formulations, and methods for their synthesis and use in disease treatment.

  2. How does this patent differ from related patents?
    It specifies particular substituents or structural features that distinguish it from prior art and related filings.

  3. Are there any known challenges or disputes related to this patent?
    No public records of legal challenges or disputes exist to date.

  4. What is the significance of patent families linked to this patent?
    They extend protection internationally, covering similar compounds and methods in multiple jurisdictions.

  5. When does this patent expire, and what does that imply?
    Expected expiration is 2041, after which generic manufacturers could enter the market if no extensions or legal obstacles occur.


References

  1. U.S. Patent and Trademark Office. (2023). Patent No. 11,903,955.
  2. Espacenet. (2023). Patent family data and related patents.
  3. WIPO. (2022). Patent filings and classifications related to medicinal chemistry.
  4. PatentScope. (2023). Patent status and legal events.
  5. US Patent Office Official Gazette. (2023). Patent examination reports.

More… ↓

⤷  Start Trial


Drugs Protected by US Patent 11,903,955

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Astrazeneca Ab FARXIGA dapagliflozin TABLET;ORAL 202293-002 Jan 8, 2014 RX Yes Yes 11,903,955*PED ⤷  Start Trial Y ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 11,903,955

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina 118963 ⤷  Start Trial
Australia 2020202887 ⤷  Start Trial
Australia 2021215150 ⤷  Start Trial
Australia 2023210548 ⤷  Start Trial
Australia 2025204486 ⤷  Start Trial
Brazil 112020008705 ⤷  Start Trial
Canada 3079175 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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