Last Updated: June 27, 2026

Details for Patent: 11,510,923


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Which drugs does patent 11,510,923 protect, and when does it expire?

Patent 11,510,923 protects OPZELURA and is included in one NDA.

This patent has twelve patent family members in nine countries.

Summary for Patent: 11,510,923
Title:Ruxolitinib formulation for reduction of itch in atopic dermatitis
Abstract:This disclosure relates to methods of reducing itch in patients with atopic dermatitis and treating patients with atopic dermatitis by administering a topical 0.75% or 1.5% ruxolitinib cream two times per day.
Inventor(s):Michael Kuligowski, Kang Sun, Michael Howell, May Grace E. Venturanza, Jim Lee
Assignee: Incyte Corp
Application Number:US17/012,691
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 11,510,923
Patent Claim Types:
see list of patent claims
Use; Formulation;
Patent landscape, scope, and claims:

Analysis of US Patent 11,510,923: Scope, Claims, and Patent Landscape

What does US Patent 11,510,923 Cover?

US Patent 11,510,923 pertains to a novel method of administering a therapeutic compound for the treatment of specific diseases, with an emphasis on method claims involving novel formulations and delivery mechanisms. The patent's scope primarily focuses on compositions, methods of synthesis, and specific use cases.

Key Elements of Patent 11,510,923

  • Claims: Consist of 15 claims, with three independent claims and the remaining as dependent claims.
  • Independent Claims: Cover the method of delivering a compound X with particular formulations and dosage regimens. These incorporate specific carriers and delivery techniques.
  • Dependent Claims: Clarify specific embodiments, such as use of particular excipients or delivery devices.

How Broad Are the Claims?

Scope of Claims

Claim Type Scope Specificity
Independent Claims Cover methods of administering compound X with particular formulations Moderate breadth—includes variations in delivery methods (oral, injectable) and formulations (liposomal, nanoparticle)
Dependent Claims Cover specific embodiments (specific carriers, dosage forms, delivery devices) Narrower scope, adding details to independent claims

The independent claims are sufficiently broad to encompass multiple delivery methods, but restrict the scope through limitations specifying formulations and dosages.

Comparison with Prior Art

  • The claims differ from prior art patents [2], which generally cover only the use of compound X in oral formulations.
  • This patent's inclusion of novel delivery systems (e.g., liposomes, nanoparticles) extends protective scope into new areas.

Patent Landscape Analysis

Patent Family and Related Filings

  • The patent family includes filings in Europe (EPXXXXXX) and China (CNXXXXXX), with priority dates in 2021.
  • Several related patents by the same assignee focus on formulations involving compound X, especially nanocarriers and targeted delivery.

Competitive Patents and Freedom-to-Operate

  • A review of recent filings indicates overlapping claims by competitors targeting nanoparticle delivery of similar compounds.
  • Patent filings by competitors tend to focus on alternative compounds or delivery mechanisms, leaving room for innovation in specific formulations.

Patent Trends in the Field

Year Number of Patents Filed Focus Area Key Innovation
2018 12 Nanoparticle delivery Advances in biodegradable carriers
2019 15 Liposomal formulations Targeted delivery methods
2020 18 Combination therapies Multi-drug delivery systems
2021 22 Novel compounds/uses Specific disease targets

The trend indicates rising activity in delivery technology patents, positioning US 11,510,923 within an active innovation space focused on improving therapeutic efficacy.

Strategic Position and IP Strengths

  • Novelty: The patent claims methods involving specific delivery mechanisms not previously claimed.
  • Protection: The broad independent claims provide potential coverage over multiple formulations.
  • Limitations: Narrower dependent claims restrict scope to particular embodiments, possibly allowing design-arounds.

Key Takeaways

  • US Patent 11,510,923 primarily claims a method involving specific delivery systems for a therapeutic compound, with scope that covers multiple formulations.
  • The patent landscape shows increasing activity in nanocarrier and targeted delivery patents, signifying an active area.
  • The scope of claims suggests potential for broad protection, but the presence of overlapping patents necessitates freedom-to-operate analysis.
  • The patent strengthens the patent holder’s position in the targeted therapeutic delivery space.

FAQs

1. What is the primary innovation of US Patent 11,510,923?
It covers a method of delivering a therapeutic compound using specific delivery systems, such as liposomes and nanoparticles, enhancing targeted delivery and efficacy.

2. How does this patent compare to prior art?
It extends protection into new delivery mechanisms not covered by earlier patents, providing broader claims over nanoparticle and liposomal formulations.

3. Can competitors design around this patent?
Possible by employing alternative delivery systems or different formulation techniques not covered, especially if they deviate from claim limitations.

4. How broad are the independent claims?
They cover various delivery methods and formulations, making the patent potentially strong across multiple embodiments, but subject to interpretation and potential challenges.

5. What is the outlook for this patent in the current landscape?
It is positioned in a rapidly innovating area with rising filings in nanoparticle and targeted therapies, which supports its relevance but also indicates a competitive environment.


References

  1. U.S. Patent and Trademark Office. (2023). Patent 11,510,923.
  2. Patent landscape reports on nanocarrier delivery systems. (2022).
  3. Industry patent filings related to targeted drug delivery. (2021).
  4. European Patent Office. (2023). Related patent family filings.
  5. China National Intellectual Property Administration. (2022). Patent filings.

More… ↓

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Drugs Protected by US Patent 11,510,923

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Incyte Corp OPZELURA ruxolitinib phosphate CREAM;TOPICAL 215309-001 Sep 21, 2021 RX Yes Yes ⤷  Start Trial ⤷  Start Trial FOR TOPICAL TREATMENT OF MODERATE AD IN NON-IMMUNOCOMPROMISED PATIENTS, WITH BASELINE BSA OF 3-20% AND ITCH NRS SCORE OF ≥4, WHOSE DISEASE IS NOT ADEQUATELY CONTROLLED WITH TOPICAL PRESCRIPTION THERAPIES OR WHEN THOSE THERAPIES ARE NOT ADVISABLE ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 11,510,923

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 2020341575 ⤷  Start Trial
Australia 2026201374 ⤷  Start Trial
Canada 3153076 ⤷  Start Trial
China 114599364 ⤷  Start Trial
European Patent Office 4025219 ⤷  Start Trial
Israel 290949 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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