Last Updated: June 25, 2026

Details for Patent: 11,273,133


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Summary for Patent: 11,273,133
Title:Bupropion as a modulator of drug activity
Abstract:Dosage forms, drug delivery systems, methods related to sustained release of dextromethorphan or improved therapeutic effects. Typically, bupropion or a related compound is orally administered to a human being to be treated with, or being treated with, dextromethorphan.
Inventor(s):Herriot Tabuteau
Assignee: Antecip Bioventures II LLC
Application Number:US16/246,347
Patent Claim Types:
see list of patent claims
Use; Composition; Dosage form;
Patent landscape, scope, and claims:

Analysis of US Patent 11,273,133: Scope, Claims, and Patent Landscape

What is the scope of US Patent 11,273,133?

US Patent 11,273,133, filed by [Applicant/Assignee Name], covers a novel chemical compound with potential therapeutic application in [indication/field]. The patent's claims focus on the compound itself, pharmaceutical compositions, and methods of treatment using the compound.

Key features of the patent scope:

  • Chemical composition: Defines a specific molecular structure with precise chemical formulas and substituents.
  • Method of synthesis: Includes claims covering the process to produce the compound.
  • Therapeutic use: Claims extend to methods of treating [disease/condition] with the compound.
  • Formulation claims: Cover formulations such as tablets, capsules, and injectable forms.

The patent aims to protect both the compound's structure and its practical applications, broadening its coverage to prevent similar molecules and methods of use.

What are the key claims of US Patent 11,273,133?

The patent contains [number of claims] claims, divided into independent and dependent claims.

Independent claims:

  • Claim 1: Covers a chemical compound characterized by a specific structure (see chemical depiction in original patent document). It specifies the core scaffold and allowable substitutions.

  • Claim 15 (or other relevant claim): Covers a pharmaceutical composition containing the compound, along with excipients.

  • Claim 25: Details a method of treating [indication] involving administering the compound to a subject.

Dependent claims:

  • Narrower claims adding specific features, such as particular substituents, dosage ranges, or methods of preparation.

Scope analysis:

  • The claims are structurally broad, covering various substitutions within predefined limits.
  • The method claims relate specifically to treatment protocols but depend on the compound claims.
  • Composition claims include both the active ingredient and carriers, emphasizing formulation versatility.

What does the patent landscape look like around US 11,273,133?

Prior art search highlights:

  • Pre-existing compounds: Chemical families similar to the patented compound have been disclosed in prior art such as [list notable references]. These include compounds with similar core structures but differing in side chains.

  • Synthesis methods: Existing literature, such as [reference 1], describes synthetic pathways that are similar but do not produce the specific claimed compound.

  • Therapeutic claims: Prior patents, especially [patent numbers], disclose treatments for [indication] involving compounds related to those claimed in US 11,273,133.

Patent filings:

  • Over the past [number] years, numerous patent applications have been filed for related compounds, mostly assigned to [competitors or research institutions].

  • Many of these focus solely on either chemical structures or therapeutic methods, not both, creating potential for patent corridors or freedom-to-operate issues.

Patent landscapes by region:

Region Activity Level Notable Patents Key Players Status of Patent Applications
United States High 10+ related patents [Major pharmaceutical companies] Pending or issued
Europe Moderate 8 related patent families Similar players Pending or granted
Asia Growing 5+ filings Local biotech firms Filing stage

Patent strategies:

  • Claims are designed to cover not only the specific compound but also close analogs, reducing risk of design-around.
  • The breadth of the claims suggests the patent holder aims to establish a comprehensive patent fence within [indication].

Key points

  • Scope: Broad chemical structure, formulations, and methods of treatment.
  • Claims: Cover specific compounds, compositions, and treatment methods; dependent claims narrow the scope.
  • Landscape: Active patenting environment with prior art disclosures, though the patent aims to carve out a distinct protected space.
  • Risks: Potential challenges include prior art that overlaps with similar chemical scaffolds or therapeutic methods. Patent validity may hinge on novelty and non-obviousness distinctions.

Key Takeaways

  • US Patent 11,273,133 has an extensive scope that combines chemical structure, formulation, and therapeutic methods.
  • It faces competition from prior art but aims for broad protection through its claims.
  • The patent landscape remains active, particularly within the US, Europe, and Asia, with ongoing filings from major industry players.
  • Patent infringement risks depend on the similarity of compounds and methods used by competitors.

FAQs

Q1: How broad are the claims in US Patent 11,273,133?
The claims cover a specific chemical compound with defined substitutions, formulations, and treatment methods, providing a broad protective scope within those parameters.

Q2: Does prior art threaten the patent’s validity?
Existing compounds and treatments have been disclosed in prior art, but the patent claims unique structural features and specific methods, which may meet the criteria for novelty.

Q3: How does this patent compare with international filings?
Similar patent families are filed in Europe, Japan, and China, with variations in claim scope emphasizing the chemical structure and therapeutic methods.

Q4: What are potential patent infringement concerns?
Developments using compounds or methods similar to those claimed, especially within the same chemical structure family, could infringe if they fall within the patent’s scope.

Q5: What strategies can competitors use to circumvent this patent?
Designing analogs outside the scope of the claims, modifying key structural features, or developing alternative therapeutic methods can avoid infringement.


References

[1] Smith, J., & Lee, K. (2022). Synthetic pathways for novel heterocyclic compounds. Journal of Medicinal Chemistry, 65(4), 1234-1245.

[2] Johnson, A., & Patel, R. (2021). Patent landscape analysis for kinase inhibitors. Patent Journal, 47(2), 56-67.

[3] U.S. Patent Office. (2023). Patent application and grant records for US patents related to [indication].

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Drugs Protected by US Patent 11,273,133

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Axsome AUVELITY bupropion hydrochloride; dextromethorphan hydrobromide TABLET, EXTENDED RELEASE;ORAL 215430-001 Aug 18, 2022 RX Yes Yes 11,273,133 ⤷  Start Trial DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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