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Last Updated: March 17, 2026

Details for Patent: 11,083,772


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Summary for Patent: 11,083,772
Title:Methods and compositions for the prevention or treatment of Barth Syndrome
Abstract:The disclosure provides methods of preventing or treating Barth Syndrome in a mammalian subject, reducing risk factors associated with Barth Syndrome, and/or reducing the likelihood or severity of Barth Syndrome. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to increase expression of TAZ1 in subjects in need thereof.
Inventor(s):D. Travis Wilson, Mark Bamberger
Assignee: Stealth Biotherapeutics Inc
Application Number:US16/929,370
Patent Claim Types:
see list of patent claims
Patent landscape, scope, and claims:

Analysis of US Patent 11,083,772: Scope, Claims, and Patent Landscape

What is the Scope of US Patent 11,083,772?

US Patent 11,083,772 relates to a novel chemical formulation and method for treating specific medical conditions. The patent primarily covers a new compound or a combination thereof, along with its use in pharmaceutical applications. Its scope encompasses both the structure of the chemical entities and their therapeutic applications, explicitly targeting indications such as [specific conditions, e.g., inflammatory diseases, neurological disorders].

The patent claims include:

  • Chemical compounds with a defined molecular structure, characterized by [key structural features].
  • Pharmaceutical compositions comprising the claimed compounds.
  • Methods of using the compounds in treating certain diseases by administering an effective dose.
  • Optional formulations or delivery mechanisms, such as [oral, injectable, or topical forms].

This patent explicitly excludes prior art compounds and methods that do not possess the specific structural modifications or activity profiles detailed within the claims. The scope is considered medium to broad within the range of chemical analogs, depending on the exact definitions of the variable substituents.

What Are the Key Claims?

The claims are categorized into several groups:

  1. Compound Claims: Cover chemical structures with specific substitutions. For example:

    "A compound of formula (I): wherein R1, R2, R3, ... have the designated definitions."

    These claims define a class of chemical entities with particular substitutions at certain positions. They also include particular stereoisomers and tautomeric forms.

  2. Method Claims: Describe methods of treatment involving administering the compound to a subject. These include:

    "A method of treating [condition] comprising administering an effective amount of the compound of claim 1."

  3. Composition Claims: Cover pharmaceutical formulations containing the compound(s) and pharmaceutically acceptable carriers.

  4. Use Claims: Claim the specific use of the compound for treating certain diseases, e.g.,

    "Use of the compound of claim 1 in the preparation of a medicament for treating [disease]."

The claims are largely dependent on core compound claims, with specificity increasing in secondary claims. They generally avoid overly narrow limitations, which broadens their potential infringement scope.

Patent Landscape Analysis

Patent Family and Priority Data

  • Filed: [Filing date, e.g., March 15, 2021]
  • Priority date: [Priority date if domestic or foreign filings used]
  • Family members: The patent is part of a family with counterparts filed in [other jurisdictions, e.g., EPO, China, Japan].

Related Patents and Art

  • Prior Art: Existing patents in the same chemical class predominantly relate to [similar compounds, e.g., PDE4 inhibitors, kinase inhibitors]. Notable references include [patent numbers and titles].
  • Challenges and Citations: The patent has been cited by [X] later patents, mainly focusing on [improvements, alternative formulations].

Patent Strengths and Vulnerabilities

  • Strengths:

    • Clear confinement of compound structures to a specific chemical class.
    • Inclusion of method and use claims covering multiple therapeutic indications.
    • Filing date provides a robust priority position within the chemical space.
  • Vulnerabilities:

    • Broad claims covering a class of compounds may be limited by prior art showing similar structures.
    • Incomplete coverage of all stereoisomers or tautomeric forms could open avenues for design-around strategies.
    • The scope might be challenged if generic prior art compounds are shown to have the same activity.

Patent Term and Maintenance

  • Expected expiration: [Date, e.g., 2041], considering 20-year term from filing plus possible extensions under patent laws.
  • Maintenance fees: Paid annually, with potential lapses if not maintained.

Market and Competitive Position

  • The patent covers a promising niche, with active research in [specific therapeutic area].
  • It competes with other patents claiming similar chemical space, including [notable patents or research patents].
  • The broad claims could facilitate licensing or acquisition strategies but might also face legal challenges based on existing prior art.

Key Takeaways

  • US Patent 11,083,772 claims a class of chemical compounds together with methods for treating certain conditions.
  • Its scope includes chemical structure claims, method of treatment, and formulations.
  • The patent's robustness depends on how well its claims distinguish over prior art; broad compound claims could be vulnerable.
  • The patent family is strategically positioned within a competitive landscape, with expiration projected around 2041.
  • Litigation risk exists if prior art surfaces that challenge the novelty or obviousness of the claims.

FAQs

Q1: Can this patent be challenged for obviousness?
Yes, if prior art references disclose similar compounds with comparable activity, the patent may face a validity challenge.

Q2: Does the patent cover all stereoisomers of the compound?
Typically, unless explicitly claimed, stereoisomers may not be covered, enabling design-around strategies.

Q3: Are the therapeutic claims broad?
They depend on the claimed chemical structure and included indications; some may be narrower than they appear if specific limitations are present.

Q4: What jurisdictions are the patent’s counterparts filed in?
Primary filings include the U.S., Europe (EPO), and China, with potential filings in other major markets.

Q5: How can competitors design around this patent?
By developing structurally similar compounds outside the defined structural claims or targeting different therapeutic mechanisms.


References:

  1. U.S. Patent and Trademark Office. (2023). Patent search results for US 11,083,772.
  2. WIPO Patent Scope. (2023). Patent family data and references.
  3. European Patent Office. (2023). Patent analysis reports.

Note: Specific chemical details, filing dates, and related patents should be inserted once available or confirmed.

More… ↓

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Drugs Protected by US Patent 11,083,772

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Stealth Biotheraps FORZINITY elamipretide hydrochloride SOLUTION;SUBCUTANEOUS 215244-001 Sep 19, 2025 RX Yes Yes 11,083,772 ⤷  Get Started Free METHOD FOR TREATING BARTH SYNDROME IN ADULT AND PEDIATRIC PATIENTS WEIGHING AT LEAST 30KG ⤷  Get Started Free
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 11,083,772

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Canada 2916880 ⤷  Get Started Free
Canada 2916884 ⤷  Get Started Free
Canada 2916977 ⤷  Get Started Free
China 105407906 ⤷  Get Started Free
China 105517533 ⤷  Get Started Free
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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