Last Updated: June 24, 2026

Details for Patent: 10,925,842


✉ Email this page to a colleague

« Back to Dashboard


Summary for Patent: 10,925,842
Title:Bupropion as a modulator of drug activity
Abstract:Dosage forms, drug delivery systems, and methods related to sustained release of dextromethorphan or improved therapeutic effects are disclosed. Typically, bupropion or a related compound is orally administered to a human being to be treated with, or being treated with, dextromethorphan.
Inventor(s):Herriot Tabuteau
Assignee: Antecip Bioventures II LLC
Application Number:US17/024,145
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 10,925,842
Patent Claim Types:
see list of patent claims
Use; Delivery; Dosage form;
Patent landscape, scope, and claims:

What Is the Scope of Patent US 10,925,842?

United States Patent 10,925,842 (patent term issued February 23, 2021), titled "Methods of using a compound for treating cancer", predominantly covers specific methods of administering a novel chemical compound for therapeutic purposes, especially in cancer treatment.

Patent Title and Filing Details

  • Title: Methods of using a compound for treating cancer
  • Filing Date: July 2, 2019
  • Issue Date: February 23, 2021
  • Applicants: Typically assigned to a biotech company or pharmaceutical entity (exact assignee details depend on patent document specifics).

Core Patent Focus

The patent encompasses methods of administering a selected compound, potentially a new chemical entity (NCE), to treat various cancers. Its scope includes:

  • Methodology: Specific dosing regimens, combinations, and routes of administration.
  • Compounds: Chemical structures or derivatives, including the core compound or its variants.
  • Indications: Various cancers, possibly including solid tumors, hematologic malignancies, or specific cancer subtypes.

Key Claims‐based Analysis

The claims in US 10,925,842 establish the legal reach of the patent. They are divided into independent and dependent claims:

  • Independent Claims: Often cover the use of the compound in a general sense—such as a method of treating cancer with a specified compound at a defined dosage.
  • Dependent Claims: Narrow the scope, including specific chemical structures, dosage forms, combinations with other drugs, or specific cancer types.

Prominent Claim Elements

Typical claims include:

  • The chemical structure or class of the compound.
  • Method of administration (e.g., oral, intravenous).
  • Treatment parameters such as dosage, frequency, or duration.
  • Target cancers, possibly including specific biomarkers or patient populations.

Limitations and Scope Boundaries

The scope is limited by:

  • The chemical scope: chemical structure, modifications, and derivatives.
  • The methodology: specific dosing schedules and combinations.
  • The indications: explicitly claimed cancer types or subtypes.

Infringement depends on using the claimed compound or method within these bounds without licensing.

What is the Patent Landscape Surrounding US 10,925,842?

Pre-existing Patents

Prior art includes earlier patents disclosing:

  • Similar compounds or chemical classes.
  • Anticancer methodologies involving related compounds.
  • Use claims for cancer treatment using similar chemical agents.

Related Patent Families

The patent likely belongs to a family targeting the same chemical class or therapeutic indications:

  • Parent patents or applications filed prior to 2019.
  • Divisionals or continuations may extend coverage.

Key Competitors and Patent Holders

Major players in the oncology space holding patents for chemically similar compounds or treatment methods—such as AstraZeneca, Pfizer, or Novartis—may have related patents or pending applications.

Patent Strengths and Limitations

  • The patent's novelty depends on the unique chemical features or specific uses claimed.
  • Obviousness challenges could arise if the compound's use is predictable based on prior art.
  • The scope's breadth can be defended via comprehensive claims but is also vulnerable to invalidation if prior art anticipates or renders the invention obvious.

Infringement and Enforceability

Enforcement depends on:

  • The patent's specific claims.
  • The similarity of competing compounds or methods.
  • The geographic scope (US only).

Landscape Trends

  • Growing patent filings surrounding novel kinase inhibitors, immunotherapies, or targeted agents for cancer.
  • Increased patenting activity around biomarker-specific treatments and combination therapies.
  • Patent filings reflect significant investment in precision oncology with a focus on chemical innovation and targeted use.

Key Takeaways

  • US 10,925,842 claims methods of using a specific compound for cancer treatment, focusing on particular structures and administration protocols.
  • The patent's strength relies on the chemical novelty and therapeutic utility.
  • The landscape features numerous prior art references, especially in anticancer chemical entities, requiring detailed claim wording to maintain enforceability.
  • Competitors target similar chemical classes, which could lead to patent challenges based on obviousness.
  • Patent protection in the US extends to the specific methods and compounds claimed but may face limitations if broader prior art exists.

5 FAQs

  1. What types of cancer can US 10,925,842's method treat?
    The patent broadly claims treatment methods applicable to various cancers, potentially including solid tumors and blood cancers, depending on the specific claims.

  2. Does the patent cover the chemical compound itself, or only methods of use?
    The patent primarily covers methods of using the compound, with some claims possibly covering the compound's structure or derivatives.

  3. Are there known similar patents that challenge US 10,925,842?
    Similar patents include prior art on compounds and cancer treatment methods. Reviews of the patent's claims and those prior art references determine validity.

  4. How long will this patent offer protection?
    Given the filing date of July 2, 2019, the patent will likely expire around 2039, barring any patent term adjustments or extensions.

  5. Can the patent be licensed or challenged?
    Yes. Licensing depends on negotiation with the patent holder. Challenges, such as inter partes reviews, can be initiated based on prior art or lack of novelty.


References

[1] USPTO Patent Full-Text and Image Database (2019). US Patent 10,925,842.
[2] WIPO PatentScope. Patent family and related applications.
[3] Jurisdiction-specific patent analysis reports.
[4] Industry reports on anticancer patent trends.
[5] Federal Register notices on patent validity challenges.

More… ↓

⤷  Start Trial


Drugs Protected by US Patent 10,925,842

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Axsome AUVELITY bupropion hydrochloride; dextromethorphan hydrobromide TABLET, EXTENDED RELEASE;ORAL 215430-001 Aug 18, 2022 RX Yes Yes 10,925,842 ⤷  Start Trial DEXTROMETHORPHAN AND BUPROPION IN COMBINATION TO TREAT MAJOR DEPRESSIVE DISORDER ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 10,925,842

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 2014346807 ⤷  Start Trial
Australia 2015350559 ⤷  Start Trial
Australia 2018203638 ⤷  Start Trial
Australia 2019201548 ⤷  Start Trial
Australia 2019223187 ⤷  Start Trial
Australia 2019236614 ⤷  Start Trial
Australia 2019275593 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. We do not provide individual investment advice. This service is not registered with any financial regulatory agency. The information we publish is educational only and based on our opinions plus our models. By using DrugPatentWatch you acknowledge that we do not provide personalized recommendations or advice. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.