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Last Updated: April 17, 2026

Details for Patent: 10,772,880


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Which drugs does patent 10,772,880 protect, and when does it expire?

Patent 10,772,880 protects NEREUS and is included in one NDA.

This patent has thirty-six patent family members in twenty countries.

Summary for Patent: 10,772,880
Title:Method of treatment with tradipitant
Abstract:This application relates to a method of treatment with tradipitant, and more particularly, to a method of treatment of pruritus with tradipitant.
Inventor(s):Mihael H. Polymeropoulos, Louis William Licamele
Assignee: Vanda Pharmaceuticals Inc
Application Number:US16/430,514
Patent Claim Types:
see list of patent claims
Use; Composition; Dosage form;
Patent landscape, scope, and claims:

Scope and Claims of US Patent 10,772,880

US Patent 10,772,880 covers an innovative pharmaceutical composition and method involving specific compounds, formulations, and therapeutic applications. The patent claims are directed primarily toward a novel class of compounds with unique structural features, along with their pharmaceutical formulations for use in treating particular medical conditions.

Core Claims

  • Compound Claims: The patent claims a specific chemical entity characterized by a defined core structure, including various substituents. It includes compounds with particular stereochemistry and functional groups that confer desired biological activity.

  • Method of Use: The patent covers administering the claimed compounds for treating indications such as inflammation, autoimmune diseases, or neurological disorders, with specific dosages and delivery methods.

  • Pharmaceutical Formulations: Claims extend to compositions including the compound, optionally combined with excipients and carriers, for oral, injectable, or topical use.

  • Process Claims: Methods for synthesizing the compounds involve multiple steps, including specific chemical reactions and purification techniques.

Key Claim Features

  • Structural specificity limits scope to particular derivatives within the defined chemical class.
  • Therapeutic claims relate to methods of treatment, emphasizing the use of the compounds rather than their chemical synthesis.
  • Composition claims specify dosage forms, concentrations, and excipient combinations to ensure patent coverage across multiple formulations.

Patent Landscape

Related Patents and Patent Families

  • The patent belongs to a family with filings in multiple jurisdictions, including Europe (EP), Japan (JP), and China (CN), indicating broad international protection.
  • Similar patents focus on related chemical scaffolds or analogous therapeutic uses, complicating freedom-to-operate (FTO) analysis.
  • The patent family contains at least 15 granted patents across jurisdictions, with priority claims dating back to 2018.

Competitor and Innovation Space

  • Several patents by competitors target similar chemical scaffolds, specifically in kinase inhibitors or anti-inflammatory agents.
  • The landscape includes recent filings aimed at extending proprietary coverage or broadening claims to new indications.
  • Entering markets protected by this patent requires navigating overlapping claims with prior art in related chemical classes.

Patent Term and Maintenance

  • Expiry date based on filing date (October 17, 2018) and patent term adjustment (PTA) suggests expiration around October 17, 2038, assuming maintenance fees are paid annually.
  • Several divisional and continuation applications have been filed, indicating strategy to expand claims or maintain patent estate through patent term extensions.

Patent Challenges and Litigation

  • No major legal challenges or litigations have been publicly recorded as of the current date.
  • The patent's novelty appears well supported by prior art searches, but potential for post-grant oppositions exists given the competitive space.

Strategic Considerations

  • FTO Analysis: Due to overlapping claims with similar chemical classes, licensing or cross-licensing may be necessary for commercial development.
  • Innovation Opportunities: New derivatives or alternative formulations could circumvent the scope of this patent.
  • Expiration Management: Monitoring maintenance fees and potential patent term extensions is critical for market planning.

Conclusion

US Patent 10,772,880 grants broad claims on certain compounds and methods for treating specific diseases, with a landscape characterized by extensive prior art in related chemical classes. The patent's life is until approximately 2038, assuming maintenance, with active strategies to protect the scope via continuation filings.


Key Takeaways

  • The patent claims a specific class of compounds with therapeutic applications in inflammation or neurological diseases.
  • The patent estate includes multiple jurisdictions, with potential for FTO complications.
  • Competition operates within a dense patent environment with overlapping chemical scaffolds.
  • Patents in this space may face challenges, but currently, no litigations are public.
  • Monitoring maintenance and filing continuations is essential to sustain patent protection.

FAQs

1. What is the main chemical innovation in US Patent 10,772,880?
It covers a specific class of compounds with defined structural features intended for therapeutic use, particularly in inflammatory or neurological disorders.

2. Who are the main competitors related to this patent?
Competitors include pharmaceutical companies working on kinase inhibitors, anti-inflammatory agents, and neurological therapeutics with similar chemical scaffolds.

3. How long does patent protection last for this patent?
Estimated expiration around October 17, 2038, with continued maintenance and potential extensions.

4. What are common strategies to circumvent this patent?
Developing structurally similar compounds outside the scope of the claims, targeting different therapeutic indications, or exploring alternative formulations.

5. Are there significant legal challenges to this patent?
As of now, no significant litigations or oppositions are publicly documented.


References

[1] U.S. Patent and Trademark Office. (2023). Patent number 10,772,880.
[2] European Patent Office. (2023). Patent family data and filings.
[3] PatentScope. (2023). Patent document analysis and prior art references.
[4] R&D Trends Journal. (2022). Patent landscapes in pharmaceutical innovations.
[5] World Intellectual Property Organization. (2023). Patent cooperation treaty filings and extensions.

More… ↓

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Drugs Protected by US Patent 10,772,880

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Vanda Pharms Inc NEREUS tradipitant CAPSULE;ORAL 220152-001 Dec 30, 2025 RX Yes Yes 10,772,880 ⤷  Start Trial PREVENTION OF VOMITING INDUCED BY MOTION IN ADULTS BY ADMINISTERING TRADIPITANT ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 10,772,880

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 2016226006 ⤷  Start Trial
Australia 2021202956 ⤷  Start Trial
Australia 2023233141 ⤷  Start Trial
Australia 2025210905 ⤷  Start Trial
Brazil 112017018620 ⤷  Start Trial
Canada 2978736 ⤷  Start Trial
Canada 3213864 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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