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Last Updated: March 28, 2024

Details for Patent: 10,654,844


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Summary for Patent: 10,654,844
Title:Dual mechanism inhibitors for the treatment of disease
Abstract: Provided are compounds that are inhibitors of both rho kinase and of a monoamine transporter (MAT) act to improve the disease state or condition. Further provided are compositions comprising the compounds. Further provided are methods for treating diseases or conditions, the methods comprising administering compounds according to the invention. One such disease may be glaucoma for which, among other beneficial effects, a marked reduction in intraocular pressure (IOP) may be achieved.
Inventor(s): deLong; Mitchell A. (Chapel Hill, NC), Sturdivant; Jill Marie (Chapel Hill, NC), Royalty; Susan M. (Davis, CA)
Assignee: Aerie Pharmaceuticals, Inc. (Bedminster, NJ)
Application Number:16/435,254
Patent Claim Types:
see list of patent claims
Use; Composition; Compound; Dosage form;

Drugs Protected by US Patent 10,654,844

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Alcon Labs Inc RHOPRESSA netarsudil mesylate SOLUTION/DROPS;OPHTHALMIC 208254-001 Dec 18, 2017 RX Yes Yes ⤷  Try a Trial ⤷  Try a Trial Y Y REDUCTION OF ELEVATED INTRAOCULAR PRESSURE ⤷  Try a Trial
Alcon Labs Inc ROCKLATAN latanoprost; netarsudil dimesylate SOLUTION/DROPS;OPHTHALMIC 208259-001 Mar 12, 2019 RX Yes Yes ⤷  Try a Trial ⤷  Try a Trial Y Y REDUCTION OF ELEVATED INTRAOCULAR PRESSURE ⤷  Try a Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 10,654,844

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 2010241996 ⤷  Try a Trial
Australia 2010242800 ⤷  Try a Trial
Australia 2016201754 ⤷  Try a Trial
Australia 2017248440 ⤷  Try a Trial
Australia 2019210632 ⤷  Try a Trial
Australia 2021204320 ⤷  Try a Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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