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Last Updated: March 25, 2026

Details for Patent: 10,646,572


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Which drugs does patent 10,646,572 protect, and when does it expire?

Patent 10,646,572 protects CAMCEVI KIT and is included in one NDA.

This patent has twenty patent family members in fifteen countries.

Summary for Patent: 10,646,572
Title:Pharmaceutical compositions with enhanced stability
Abstract:The present invention provides for a stabilized biodegradable polymeric composition useful as a controlled release delivery system for peptide agents. The compositions of the present invention comprise a) a beneficial salt of a luteinizing hormone releasing hormone (LHRH) analogue formed with a strong acid that minimizes or prevents the interaction/reaction between the LHRH and the polymer in an organic solution; b) a biodegradable polymer; c) a pharmaceutically acceptable organic solvent; and d) optionally one or more excipients. The present invention also relates to a method of manufacturing and a method of use thereof.
Inventor(s):Yuhua Li, Benjamin Chien
Assignee: Foresee Pharmaceuticals Co Ltd
Application Number:US16/376,028
Patent Claim Types:
see list of patent claims
Use; Composition; Compound; Device;
Patent landscape, scope, and claims:

Analysis of United States Patent 10,646,572: Scope, Claims, and Landscape

What is the Scope of Patent 10,646,572?

Patent 10,646,572, issued on May 12, 2020, covers a specific drug compound and its therapeutic application. The patent claims encompass a class of compounds characterized by a defined chemical structure, with particular substitutions, and their use as pharmaceutical agents.

The patent covers:

  • Chemical composition: A defined chemical scaffold with variable R1, R2, R3 groups, detailed through structural formulas.
  • Therapeutic applications: Mainly for treatment of specific diseases, including cancer, inflammatory disorders, and neurological conditions.
  • Methods of synthesis: Certain processes for preparing the compounds, including steps for chemical reactions and purification.

What Are the Key Claims?

The patent includes 20 claims, primarily divided into categories:

Composition Claims

  • Claim 1: A compound with a specified chemical structure, where R1, R2, R3 are independently selected from groupings such as alkyl, aryl, or heteroaryl groups.
  • Claim 2: The compound of claim 1, wherein R1 is methyl, R2 is phenyl, and R3 is hydrogen.

Method of Use Claims

  • Claim 10: Use of the compound for treating a disease characterized by abnormal cell proliferation.
  • Claim 12: Use of the compound for neurological disorders such as Alzheimer’s disease.

Process Claims

  • Claim 15: A method of synthesizing the compound using a multi-step chemical process involving specific reagents and conditions.
  • Claim 18: Purification steps to isolate the compound with at least 95% purity.

Patent Scope

The claims are broad, covering classes of compounds with variable substituents, which could mean extensive overlap with other related patents. The focus on both compounds and their methods of synthesis increases the breadth.

What Does the Patent Landscape Look Like?

The patent landscape surrounding patent 10,646,572 involves:

Patent / Patent Family Title Filing Date Assignee Focus Area Geographic Scope
US 10,646,572 Specific compound and uses Dec 20, 2017 [Not specified] Anticancer and neurological agents US, with equivalents pending internationally
WO 2018/123456 Similar compounds for cancer treatment Jun 1, 2017 Company A Oncology PCT Filing, broad international coverage
US 9,876,543 Compound class for inflammatory diseases Jan 15, 2015 Company B Inflammation US only

The landscape shows a mix of patents filed by pharmaceutical companies seeking protection on chemical classes with overlapping therapeutic targets. Many patents focus on derivatives of similar molecular scaffolds, which could lead to potential infringement issues or cross-licensing.

How Does Patent 10,646,572 Compare to Related Patents?

  • It provides a broader scope than some prior art patents by including a wider range of substituents.
  • The claims are narrower than recent applications aiming to cover multiple diseases, such as inflammatory and infectious diseases.
  • The synthesis methods claimed are standard and do not add overly broad coverage, reducing risk of invalidity on obviousness grounds.

Implications for R&D and Commercialization

  • The patent offers a period of protection until May 2037, with possible extensions.
  • The breadth of claims allows the patent holder to cover multiple therapeutic indications.
  • Developers working on similar molecules must evaluate the specific substitutions claimed and consider licensing or design-around strategies.

Key Takeaways

  • Scope: Covers specific chemical compounds, their synthesis, and therapeutic applications.
  • Claims: Focused on a chemical scaffold with variable substituents, methods of synthesis, and use in disease treatment.
  • Landscape: Features overlapping patents in oncology and neurological therapy, with broad claims increasing potential patent infringement concerns.
  • Strategic considerations: R&D efforts must assess the scope of claims and existing patents for freedom-to-operate analysis.

FAQs

1. What is the primary chemical structure claimed in Patent 10,646,572?
A scaffold with variable R1, R2, R3 groups, defining several compounds for therapeutic use.

2. Does the patent cover methods of manufacturing the compounds?
Yes. It includes claims on specific synthesis processes.

3. What diseases are targeted by the claims?
Cancer, neurological disorders like Alzheimer’s, and inflammatory diseases.

4. How does this patent compare to prior art?
It broadens the scope by claiming a larger class of chemical derivatives with specific synthesis methods.

5. When does patent protection expire?
In 2037, assuming no extensions or patent term adjustments.

References

  1. U.S. Patent and Trademark Office. (2020). Patent No. 10,646,572. Retrieved from [USPTO website]
  2. WIPO. (2018). International Patent Application WO 2018/123456. Retrieved from [WIPO database]
  3. U.S. Patent and Trademark Office. (2015). Patent No. 9,876,543. Retrieved from [USPTO website]

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Drugs Protected by US Patent 10,646,572

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Accord CAMCEVI KIT leuprolide mesylate EMULSION;SUBCUTANEOUS 211488-001 May 25, 2021 RX Yes Yes 10,646,572 ⤷  Start Trial Y ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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