Last Updated: June 22, 2026

Details for Patent: 10,597,377


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Summary for Patent: 10,597,377
Title:Somatostatin modulators and uses thereof
Abstract:Described herein are compounds that are somatostatin modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity.
Inventor(s):Jian Zhao, Shimiao Wang, Yunfei ZHU
Assignee: Crinetics Pharmaceuticals Inc
Application Number:US16/407,031
Patent Claim Types:
see list of patent claims
Use; Composition;

Drugs Protected by US Patent 10,597,377

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Crinetics PALSONIFY paltusotine hydrochloride TABLET;ORAL 219070-001 Sep 25, 2025 RX Yes No 10,597,377 ⤷  Start Trial Y Y TREATMENT OF ADULTS WITH ACROMEGALY WHO HAD AN INADEQUATE RESPONSE TO SURGERY AND/OR FOR WHOM SURGERY IS NOT AN OPTION ⤷  Start Trial
Crinetics PALSONIFY paltusotine hydrochloride TABLET;ORAL 219070-002 Sep 25, 2025 RX Yes Yes 10,597,377 ⤷  Start Trial Y Y TREATMENT OF ADULTS WITH ACROMEGALY WHO HAD AN INADEQUATE RESPONSE TO SURGERY AND/OR FOR WHOM SURGERY IS NOT AN OPTION ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 10,597,377

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 2017296392 ⤷  Start Trial
Australia 2020277122 ⤷  Start Trial
Brazil 112019000692 ⤷  Start Trial
Canada 3030423 ⤷  Start Trial
China 109715612 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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