Claims for Patent: 10,597,377

Summary for Patent: 10,597,377

Title:	Somatostatin modulators and uses thereof
Abstract:	Described herein are compounds that are somatostatin modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity.
Inventor(s):	Jian Zhao, Shimiao Wang, Yunfei ZHU
Assignee:	Crinetics Pharmaceuticals Inc
Application Number:	US16/407,031
Patent Claims:	1. A compound that has the following structure: or a pharmaceutically acceptable salt, or solvate thereof. 2. A compound that has the following structure: 3. A pharmaceutically acceptable salt of a compound that has the following structure: or a solvate thereof. 4. A pharmaceutical composition comprising a compound that has the following structure: or a pharmaceutically acceptable salt, or solvate thereof; and at least one pharmaceutically acceptable excipient. 5. The pharmaceutical composition of claim 4, comprising a pharmaceutically acceptable salt of the compound that has the following structure: 6. A method of treating acromegaly, a neuroendocrine tumor, or a combination thereof in a human comprising administering to the human in need thereof a compound that has the following structure: or a pharmaceutically acceptable salt, or solvate thereof. 7. The method of claim 6, comprising administering to the human in need thereof a pharmaceutically acceptable salt of the compound that has the following structure: 8. A method of treating acromegaly in a human comprising administering to the human in need thereof a compound that has the following structure: or a pharmaceutically acceptable salt, or solvate thereof. 9. The method of claim 8, comprising administering to the human in need thereof a pharmaceutically acceptable salt of the compound that has the following structure: