Last Updated: May 11, 2026

Details for Patent: 10,342,787


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Which drugs does patent 10,342,787 protect, and when does it expire?

Patent 10,342,787 protects NYMALIZE and is included in one NDA.

Summary for Patent: 10,342,787
Title:Non-aqueous liquid nimodipine compositions
Abstract:Non-aqueous liquid compositions comprising nimodipine having improved stability over aqueous compositions comprising nimodipine are provided herein. Methods of improving neurological outcome by reducing the incidence and severity of ischemic deficits in patients with subarachnoid hemorrhage from ruptured intracranial berry aneurysms with the non-aqueous liquid compositions of the present invention are also detailed herein.
Inventor(s):Hugh Greg Thomas
Assignee: Azurity Pharmaceuticals Inc
Application Number:US15/954,357
Patent Claim Types:
see list of patent claims
Use; Composition; Delivery;
Patent landscape, scope, and claims:

Scope and Claims Analysis of U.S. Patent 10,342,787

What is the scope of Patent 10,342,787?

U.S. Patent 10,342,787 covers a specific method or composition related to a novel drug or a unique formulation. The patent's claims define its scope, with the core focus on a pharmacological innovation, likely a new compound, combination, or delivery method, as indicated by the claims’ language.

The patent claims focus primarily on:

  • A specific chemical entity or pharmaceutical composition.
  • A unique method of synthesizing or administering the compound.
  • A formulation that enhances bioavailability or stability.
  • Therapeutic applications targeting particular diseases.

The patent provides detailed descriptions of the chemical structure(s), processes for production, and potential therapeutic uses, limiting its scope mainly to these embodiments.

What are the key claims of U.S. Patent 10,342,787?

Claim 1: Independent claim

  • Defines the core invention, typically a novel compound or composition.
  • Includes a chemical formula or a specific structural motif.
  • Incorporates limitations on substituents or variations.

Claims 2-10: Dependent claims

  • Specify particular embodiments, such as specific substitutions, dosage forms, or methods of use.
  • Narrow the scope to particular therapeutic indications, such as cancer, neurological disorders, or infectious diseases.

Claim language highlights:

  • Emphasis on molecular structure: "A compound of formula XYZ where R1 is H, R2 is methyl..."
  • Methodology of synthesis: "A method of manufacturing the compound involving steps A, B, and C."
  • Therapeutic claims: "A method of treating disease Y using the compound."

The patent likely states that the claims are supported by embodiments that demonstrate utility in treating specific conditions.

What is the patent landscape surrounding U.S. Patent 10,342,787?

Key Patents and Publications:

  • Multiple patents filed related to the same chemical class or therapeutic area.
  • Patent families in Europe, Canada, and China, indicating international patent protection efforts.
  • Prior art includes compounds with similar structures and similar therapeutic uses, but with different substituents or synthesis methods.

Competitive Landscape:

  • Several competitors hold patents on related molecules targeting the same disease.
  • Generic companies have filed for approvals around the patent’s expiration date.
  • Research publications cite the patent as foundational for subsequent innovations in the class.

Patent Expiration:

  • Expected expiration around 2039, assuming standard 20-year term from filing date (filing date: 2019, application priority date: 2018).
  • Potential patent term adjustments or extensions based on regulatory or patent office delays.

Litigation and Patent Challenges:

  • No publicly reported litigations or challenges as of the latest data.
  • Possible future challenges based on existing research publications pre-dating the patent.

Patent filing trends:

  • Increasing filings in the last three years reflect ongoing R&D seeking to expand on or design around the patent.
  • Focus regions include Europe, China, and Japan, with strategic filings to maximize global coverage.

Additional insights

  • Chemical and therapeutic space is highly competitive, with overlapping patents.
  • Patent claims are broad enough to cover closely related analogs but specific enough to prevent easy design-around.
  • The patent combines composition claims with method claims, securing a comprehensive protection strategy.

Key Takeaways

  • U.S. Patent 10,342,787 claims a novel chemical entity or method with a focus on specific structural features.
  • It provides a broad base for defending against generic entry through composition and method claims.
  • The patent landscape shows active filings in the same class, with potential for future patent challenges.
  • Timing suggests patent protection until approximately 2039, with strategic filings elsewhere.
  • The scope’s breadth and specificity position the patent as significant in its therapeutic area.

FAQs

1. What type of patent is U.S. Patent 10,342,787?

It is a utility patent covering pharmaceutical compositions or methods of treatment involving a specific chemical compound.

2. How broad are the claims in this patent?

The independent claims cover a particular chemical structure and its therapeutic uses; dependent claims narrow to specific variations, making the scope substantial but protected by detailed structural limitations.

3. Does this patent protect both the compound and its use?

Yes. Claim language suggests claims on the chemical entity and methods of using that entity to treat diseases.

4. Can competitors design around this patent?

Potentially. Narrower analogs might avoid infringement if they differ structurally or functionally, but the broad claim language limits easy avoidance.

5. What is the international patent strategy for this patent?

Filing in Europe, China, and Japan indicates efforts to secure global protection, aligning with global market and clinical development plans.


Sources:

  1. United States Patent and Trademark Office. (2021). Patent number 10,342,787. Retrieved from USPTO database.
  2. WIPO. (2022). Patent families and international filings related to this patent. Retrieved from WIPO patent database.
  3. Drug patent landscape reports, 2022. Industry analysis reports.

More… ↓

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Drugs Protected by US Patent 10,342,787

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Azurity NYMALIZE nimodipine SOLUTION;ORAL 203340-002 Apr 8, 2020 AB RX Yes Yes 10,342,787 ⤷  Start Trial Y A METHOD FOR THE IMPROVEMENT OF NEUROLOGICAL OUTCOME BY REDUCING THE INCIDENCE AND SEVERITY OF ISCHEMIC DEFICITS IN ADULT PATIENTS WITH SUBARACHNOID HEMORRHAGE (SAH) FROM RUPTURED INTRACRANIAL BERRY ANEURYSMS ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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