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US Department of Justice
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Generated: December 15, 2018

DrugPatentWatch Database Preview

Details for Patent: 10,016,415

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Summary for Patent: 10,016,415
Title:Aripiprazole prodrug compositions
Abstract: Described is a composition comprising (a) a population of particles of an aripiprazole prodrug having a volume based particle size (Dv50) of less than 1000 nm and (b) at least one surface stabilizer comprising an adsorbed component which is adsorbed on the surface of the aripiprazole prodrug particles and a free component available for solubilization of the aripiprazole prodrug. The surface stabilizer to prodrug ratio provides the optimal quantity of free surface stabilizer for the purposes of producing a lead-in formulation. Also described are methods of treatment using the aforementioned composition.
Inventor(s): Cresswell; Philip (Athlone, IE), Paquette; Sara Montminy (Hudson, MA), Hickey; Magali (Westwood, MA), Perkin; Kristopher (Athlone, IE), Smith; Greg (Norton, MA), Liversidge; Elaine (Charlestown, MA), Steinberg; Brian (Arlington, MA), Manser; David (Keenagh, IE), Turncliff; Ryan (Ashland, MA), Palmieri, Jr.; Michael (Hopkinton, MA), Zeidan; Tarek (Waltham, MA), Cash; Ethan P. (Sudbury, MA), Hard; Marjie L. (Lexington, MA)
Assignee: ALKERMES PHARMA IRELAND LIMITED (Dublin, IE)
Application Number:14/828,229
Patent Claim Types:
see list of patent claims

Drugs Protected by US Patent 10,016,415

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Alkermes Inc ARISTADA INITIO KIT aripiprazole lauroxil SUSPENSION, EXTENDED RELEASE;INTRAMUSCULAR 209830-001 Jun 29, 2018 RX Yes No ➤ Try a Free Trial ➤ Try a Free Trial Y ➤ Try a Free Trial
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate

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International Family Members for US Patent 10,016,415

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 2015306198 ➤ Try a Free Trial
Brazil 112017002926 ➤ Try a Free Trial
Canada 2957762 ➤ Try a Free Trial
China 106794251 ➤ Try a Free Trial
European Patent Office 3182958 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Dow
Johnson and Johnson
AstraZeneca
Covington
US Army
Medtronic
Fish and Richardson
Teva
Federal Trade Commission

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