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Last Updated: September 17, 2021

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Details for Patent: 10,016,415

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Summary for Patent: 10,016,415
Title:Aripiprazole prodrug compositions
Abstract: Described is a composition comprising (a) a population of particles of an aripiprazole prodrug having a volume based particle size (Dv50) of less than 1000 nm and (b) at least one surface stabilizer comprising an adsorbed component which is adsorbed on the surface of the aripiprazole prodrug particles and a free component available for solubilization of the aripiprazole prodrug. The surface stabilizer to prodrug ratio provides the optimal quantity of free surface stabilizer for the purposes of producing a lead-in formulation. Also described are methods of treatment using the aforementioned composition.
Inventor(s): Cresswell; Philip (Athlone, IE), Paquette; Sara Montminy (Hudson, MA), Hickey; Magali (Westwood, MA), Perkin; Kristopher (Athlone, IE), Smith; Greg (Norton, MA), Liversidge; Elaine (Charlestown, MA), Steinberg; Brian (Arlington, MA), Manser; David (Keenagh, IE), Turncliff; Ryan (Ashland, MA), Palmieri, Jr.; Michael (Hopkinton, MA), Zeidan; Tarek (Waltham, MA), Cash; Ethan P. (Sudbury, MA), Hard; Marjie L. (Lexington, MA)
Application Number:14/828,229
Patent Claim Types:
see list of patent claims
Composition; Compound;

Drugs Protected by US Patent 10,016,415

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Alkermes Inc ARISTADA INITIO KIT aripiprazole lauroxil SUSPENSION, EXTENDED RELEASE;INTRAMUSCULAR 209830-001 Jun 29, 2018 RX Yes No ⤷  Try it Free ⤷  Try it Free Y ⤷  Try it Free
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 10,016,415

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 2015306198 ⤷  Try it Free
Brazil 112017002926 ⤷  Try it Free
Canada 2957762 ⤷  Try it Free
China 106794251 ⤷  Try it Free
China 112494492 ⤷  Try it Free
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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