Last Updated: June 27, 2026

Competitive Generic Therapies: Off-Patent Drugs With 2 Sources

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This table lists drugs which, despite having no patents or regulatory protections, have a limited number of active sources.

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Strength
Apotex	ADEFOVIR DIPIVOXIL	adefovir dipivoxil	TABLET;ORAL	205459-001	Jul 6, 2018	AB	RX	No	No	10MG
Sigmapharm Labs Llc	ADEFOVIR DIPIVOXIL	adefovir dipivoxil	TABLET;ORAL	202051-001	Aug 29, 2013	AB	RX	No	Yes	10MG
Organon Llc	FOSAMAX PLUS D	alendronate sodium; cholecalciferol	TABLET;ORAL	021762-001	Apr 7, 2005		RX	Yes	No	EQ 70MG BASE;2,800 IU
Organon Llc	FOSAMAX PLUS D	alendronate sodium; cholecalciferol	TABLET;ORAL	021762-002	Apr 26, 2007		RX	Yes	Yes	EQ 70MG BASE;5,600 IU
Barr	AMILORIDE HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE	amiloride hydrochloride; hydrochlorothiazide	TABLET;ORAL	071111-001	May 10, 1988	AB	RX	No	No	EQ 5MG ANHYDROUS;50MG
Rising	AMILORIDE HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE	amiloride hydrochloride; hydrochlorothiazide	TABLET;ORAL	073209-001	Oct 31, 1991	AB	RX	No	Yes	EQ 5MG ANHYDROUS;50MG
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Strength

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