Phosphate Chelating Activity Market Analysis and Financial Projection
The global market for drugs with phosphate chelating activity is experiencing significant growth, driven by rising demand across therapeutic and industrial applications. Below is an analysis of key market dynamics and patent trends:
Market Dynamics
Phosphate-Binding Therapeutics
The hyperphosphatemia treatment market is projected to reach $4.72B by 2030 (CAGR: 3.67%)[7], with phosphate binders dominating CKD patient care[18]. Leading products include:
Sevelamer (Renvela®): Accounts for ~30% of non-calcium binder sales, with patents expiring in 2030[9].
Tenapanor (Xphozah®): FDA-approved in 2023 as the first non-binder phosphate absorption inhibitor, reducing pill burden by 80% compared to traditional binders[12][19].
The sector will see increased integration of dual-purpose chelators, exemplified by Vifor Pharma’s nanoparticle delivery systems[13]. With 22.9% CAGR for RTU phosphate injections in CKD care[4][12], next-gen therapies will prioritize reduced dosing frequency and IoT-enabled administration tracking.
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